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15 Cards in this Set
- Front
- Back
Psychoactive drug
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substance taken to change how you feel
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Addictions
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continued use, in spite of negative consequences
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Signs of Dependence
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Increased Tolerance
Withdrawl Desire to reduce or control use |
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Biopsychosocial model of addiction
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Bio-genetic predisposition, DA reward pathway
Psych-self medicating, low self-esteem, personality disorder Social- early trauma, enviornment, dys family |
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Gender differences in drug use
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Men= higher rates of dependence and abuse. Heroin, cocaine
Women= prescription drugs |
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Wernickes's syndrome
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Thiamine deficiency caused by excessive alcohol intake. Symptoms=ataxia, altered eye movement, confusion. Reversible in early stages
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Korsakoff's syndrome
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follows wernicke's, retrograde and anterograde amnesia, confabulation, edema
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Alcohol:
Effect, adverse, PK |
general anaesthetic, decreases REM sleep.
Metabolized:1oz/hr by aldehyde dehydrogenase |
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Nicotine
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Increases DA, NE, ACH
Increases cognition, decreases appetite |
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CNS depressants
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disinhibition, impaired judgement, psychomotor impairment, confusion stupor
withdrawl= gi upset, malaise |
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Cocaine
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1.5 million americans
high lasts 30-60 min, alertness, self confidence, euphoria increases 5HT, NE, DA Withdrawal- decrease NE=Increase sleep, decrease DA= depression Tx- antidepressants, DA agonists |
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Amphetamines
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blocks reuptake of NE
agitation, aggression, psychosis, impaired judgement, elevated HR and BP, diaphoresis |
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Narcotics
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Bind to opiate receptors
rapid physical dependence Side effects-constipation, respiratory depression |
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Methamphetamine
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increases DA 12x
dry mouth, tooth decay, N/V/D, decreased appetite increase sex drive, respiration & irritability |
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Date Rape Drugs
GHB & Rohypnol |
disinhibition, unconciousness, relax voluntary muscles, anterograde memory
exacerbated by alcohol |