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15 Cards in this Set

  • Front
  • Back
Psychoactive drug
substance taken to change how you feel
Addictions
continued use, in spite of negative consequences
Signs of Dependence
Increased Tolerance
Withdrawl
Desire to reduce or control use
Biopsychosocial model of addiction
Bio-genetic predisposition, DA reward pathway
Psych-self medicating, low self-esteem, personality disorder
Social- early trauma, enviornment, dys family
Gender differences in drug use
Men= higher rates of dependence and abuse. Heroin, cocaine
Women= prescription drugs
Wernickes's syndrome
Thiamine deficiency caused by excessive alcohol intake. Symptoms=ataxia, altered eye movement, confusion. Reversible in early stages
Korsakoff's syndrome
follows wernicke's, retrograde and anterograde amnesia, confabulation, edema
Alcohol:
Effect, adverse, PK
general anaesthetic, decreases REM sleep.
Metabolized:1oz/hr by aldehyde dehydrogenase
Nicotine
Increases DA, NE, ACH
Increases cognition, decreases appetite
CNS depressants
disinhibition, impaired judgement, psychomotor impairment, confusion stupor
withdrawl= gi upset, malaise
Cocaine
1.5 million americans
high lasts 30-60 min, alertness, self confidence, euphoria
increases 5HT, NE, DA
Withdrawal- decrease NE=Increase sleep, decrease DA= depression
Tx- antidepressants, DA agonists
Amphetamines
blocks reuptake of NE
agitation, aggression, psychosis, impaired judgement, elevated HR and BP, diaphoresis
Narcotics
Bind to opiate receptors
rapid physical dependence
Side effects-constipation, respiratory depression
Methamphetamine
increases DA 12x
dry mouth, tooth decay, N/V/D, decreased appetite
increase sex drive, respiration & irritability
Date Rape Drugs
GHB & Rohypnol
disinhibition, unconciousness, relax voluntary muscles, anterograde memory
exacerbated by alcohol