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10 Cards in this Set
- Front
- Back
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What "lights up" when addicts are offered their drugs?
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The nucleus accumbens
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What role does dopamine play?
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Reward
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What role does glutamate play?
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Learning/memory
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What role does Seratonin play?
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Mood, sleep, memory
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What role does CRF play?
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Stress
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Do all drugs work at the same place in the brain?
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Yes
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What are the specific changes in neurotransmitters in response to drug use?
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Increase dopamine release from ventral tegmental area to nucleus accumbens, decreased response of VTA and Nucleus accumbents to glutamate
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What are the long term effects of drug use on specific dopamine receptors?
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Icnreased D1 receptors, Decreased D2 receptors
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What individuals may be genetically at risk for drug addiction?
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Individuals with low numers of D2 receptors
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What is the role or CREB in addiction?
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Decreased cAMP stimulates CREB to increase production of proteins that dampen the reward circitry -> dependence
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