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30 Cards in this Set

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  • Back
246. Tx of IBS?
a. Usually, no specific tx is necessary.
b. Manage diarrhea/constipation sx as indicated below.
c. These may help: Avoidance of dairy, avoid excessive caffeine
247. Drug specifically indicated for tx of IBS?
a. Tegaserod maleate (Zelnorm).
248. MOA of Tegaserod maleate (Zelnorm)?
a. It is a serotonin agonist recently introduced for the treatment of IBS.
b. In a short-term study, it improved abdominal pain, bloating, and constipation in Women.
249. Tx of diarrhea associated w/IBS (2)?
a. Diphenoxylate, loperamide
250. Tx of constipation associated with IBS (3)?
a. Colace
b. Psyllium
c. Cisapride
251. What features must frequently be excluded in the diagnosis of IBS?
a. Obstruction (plain abdominal films)
b. IBD
c. Lactose or sorbitol intolerance
d. Malignancy (in older pts or those w/family hx)- colonoscopy, occult blood in stools.
252. 2 most common causes of N/V?
1. Viral gastroenteritis
2. Food poisoning.
253. 5 metabolic causes of N/V?
a. Diabetic ketoacidosis
b. Addisonian crisis
c. Uremia
d. Electrolyte disturbance- Hypercalcemia, hypokalemia
e. Hyperthyroidism
254. GI causes of N/V?
a. Gastroenteritis
1. Viral (most common)
2. Food poisoning (e.g., salmonella, shigella)
3. Cholera
b. PUD
c. GERD
d. Gastric retention – Gastroparesis (diabetic pts), gastric outlet obstruction.
e. Intestinal obstruction (small bowel obstruction, or pseudo-obstruction), ileus
f. Peritonitis
255. Acute visceral conditions causing N/V?
a. Pancreatitis
b. Appendicitis
c. Pyelonephritis
d. Cholecystitis
e. Cholangitis
256. Neurologic causes of N/V?
a. Increased ICP
b. Vestibular disturbance (vertigo)
c. Migraine HA.
257. Cardiac cause of N/V?
a. Acute MI
258. Drug cause of N/V?
a. Chemo meds (cisplatin especially)!
b. Digitalis toxicity
c. NSAIDs, aspirin
d. Narcotics
Abx (erythromycin)
259. Misc causes of N/V?
a. Excessive ETOH intake (after binge drinking and morning-after hangover).
b. Motion sickness
c. Systemic illness
d. Radiation therapy
e. Postop
260. Psych causes of N/V?
a. Eating disorder
b. Anxiety
261. Bilious vomiting, think of?
a. Obstruction distal to ampula of Vatar
262. Feculent vomiting, think of?
a. Distal intestinal obstruction
b. Bacterial overgrowth
c. Gastrocolic fistula.
263. Vomiting of undigested food?
a. Oesophageal problem more likely (achalasia, stricture, diverticulum
264. Projectile vomiting?
a. Increased intracranial pressure or pyloric stenosis
265. Coffee-ground vomiting or blood?
a. GI bleeding.
266. What does diarrhea and fever as accompanying symptoms with N/V suggest?
a. Infectious cause (gastroenteritis)
267. Abdominal pain accompanying N/V suggests?
a. Obstruction
b. Acute inflammatory conditions (e.g., peritonitis, cholecystitis).
268. What do HA, visual disturbances, and other neurologic findings along w/N/V point to?
a. Increased ICP or Intraocular pressure.
269. Note: Be sure to always order a pregnancy test in any woman of child-bearing age w/n/v?
269. Note: Be sure to always order a pregnancy test in any woman of child-bearing age w/n/v?
270. Tx of N/V?
a. Most causes are self-limiting.
b. If vomiting is severe it may cause dehydration requiring hospitalization.
c. Assess hydration status- Fluid replacement is the first step in management; use ½ NS with potassium replacement.
271. Rx Symptomatic relief of N/V?
a. Prochloroperazine (Compazine) and Promethazine (Phenergan) are commonly used.
272. Symptomatic relief of N/V?
a. Follow a liquid diet (liquid is cleared from the stomach more quickly than solids).
b. Avoid large meals and fatty meals.
c. Nasogastric suction may improve symptoms.
273. Possible complications of severe of prolonged or prolonged vomiting?
a. Fluid/electrolyte:
1. Dehydration
2. Metabolic alkalosis
3. Hypokalemia
b. Dental caries
c. Aspiration pneumonitis
274. GI complications of severe or prolonged vomiting?
a. Mallory-Weiss tears
b. Boerhaave’s syndrome
c. Mallory-Weiss syndrome.
275. Most common abnormality seen after severe vomiting?
a. Hypokalemia w/metabolic alkalosis.