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4 Cards in this Set
- Front
- Back
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1st gen anti psychotics
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typical antipsychotics are dopamine D2 antagonists
-Effective only for positive symptoms/type 1 -Side effects: Parkinson like syndrome/tardive dsykinesia |
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2nd gen anti psychotics
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Atypical are both D2 receptor and serotonin (5-HT2A) Antagonists
-Effective for all symptoms except cognitive disfunction |
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Anti pyschotic drugs: glutamate-glycine
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-suggests that glutamate and/or NMDA receptors are down regulated in schizo
-use a co-agonist=glycine -appears to be effective at both negative type symptoms are cognitive disfunction |
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1st gen anti depressants
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MAOI's- Mono Oxidase Inhibitors inhibit the breakdown of dopamine, norepinephrine and serotonin
-builds a tyramine tricyclic |
