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79 Cards in this Set

  • Front
  • Back
commonly see in states of dehydration resulting from water loss due to excessive vomiting
diarrhea
Your patients urine is cloudy in appearance
what is the problem? Intact red blood cells
Your patients urine is pink and clear what is the problem it has hemoglobin
myoglobin or porphyrins present in the urine
What color does methemoglobin turn urine to? Brown
black. Upon standing
What color does melanin turn the urine Upon standing
neutral pH urine will turn black if melanin is present in the urine sample
What causes the urine to have WBC
RBC
When the urine is cloudy or turbid
is this normal No
What does bacterial infections
elevated ketones
What is the normal value of protein in the urine Negative
Trace or trace dipstick reading (<= 150mg/day)
How are abnormally high protein values reported 3+
4+
What is sulfosalicylic Acid (SSA) Confirmatory test
used to retest all specimens with positive chemstrip results (1+ to 4+)
Can you find the presence of microalbumin in a routine chemstrip testing no
you must use the spot method
Causes of renal protein uria caused by kidney diseases
primary or induced glomerular proteinuria: protein leaks through gomerulus
Renal proteinuria: primary Glomerulonephritis
nephrotic syndrome
Renal proteinuria: induced Drugs or toxins
systemic disease
Average adult daily output volume
1200-1500 mL
Polyuria
increase in daily output of urine (> 3L/day)
Diabetes mellitus in polyuria
excess glucose in blood leads to high concentration of glucose in filtrate exceeding the renal threshold. urine looks dilute but has a high osmolality
commonly see in states of dehydration resulting from water loss due to excessive vomiting
diarrhea
What causes auria
any serious damage to the kidneys or a decrease in blood flow to the kidneys
Decreased production or function of ADH affecting the nephron's ability to concentrate urine through water reabsorption
Diabetes insipidus: urine is dilute with a low osmolality
Variations in the yellow color of urine reflect what
the body's hydration status
Why would the urine be an amber beer brown
due to the presence of conjugated bilirubin
Why would the urine be red or pink and clear
hemoglobin or myoglobin or porphyrins
Your patients urine is cloudy in appearance
what is the problem?
Your patients urine is pink and clear what is the problem
it has hemoglobin
What color does methemoglobin turn urine to?
Brown
What color does homogentisic acid turn the urine
brown/black upon standing alkaline urine will turn brown if homogentisic acid is present in the urine sample
Alkaptonuria
a metabolic defect. increased excretion in occurs in the disease
What color does melanin turn the urine
Upon standing
Why will melanin appear in the urine
the patient has metastatic malignant melanoma (an aggressive form of skin cancer)
What color does Pyridium (phenazopyriding) turn the urine?
dark orange. antibiotic rifampicin
How does normal urine look
clear or hazy
How does amorphous crystal make the urine look
a normal clear or hazy
How does squamous epithelial cells make the urine look?
a normal clear or hazy
How does seminal fluid make the urine look
a normal clear or hazy
how does fecal contamination make the urine look
a normal clear or hazy
how does mucus make the urine look
a normal clear or hazy
What causes the urine to have WBC
RBC
When the urine is cloudy or turbid
is this normal
How does normal freshly voided urine smell
pungent odor of volatile aromatic acids
What does bacterial infections
elevated ketones
How is the chemical analysis of urine accomplished?
Utilization of a urine chemstrip or dipstick
What is the normal value of protein in the urine
Negative
What is the significance of urine pH?
Aids in identifying acid base disorders
When is acidic urine produced
Respiratory or metabolic acidosis - not related to renal function disorders
When is alkaline urine produced
Respiratory or metabolic alkalosis
How are abnormally high protein values reported
3+
How much proteins are reabsorbed by the tubules?
95-99%. Only the smallest proteins are filtered from the plasma into the urine
What are Tamm-Horsfall protein
muco protein synthesized by the distal tubular cells and involved in cast formation
What is the chemstrip most sensitive to
the presence of albumin-although globulin are the major protein fraction found in urine
What is sulfosalicylic Acid (SSA)
Confirmatory test
When the SSA test confirms the presence of protein what should you order
24 hour urine protein
What does the 24hr urine provide
quantify the amount of protein that is being secreted per day. It averages out normal variations in urine concentration
What do you order if the 24hr urine is > 150 mg/day
a urine protein electrophoresis procedure is performed to identify proportions of albumin and other proteins
Why would a 24hr urine protein be ordered for patients with diabetes melitus and hypertension
to screen for nephropathy
What is most commonly performed on a spot urine specimen from a diabetic patient
albumin to creatinine ratio
What is the most common screening test for the presence of microalbumin in the urine
Spot Method
What test is used to diagnose diabetic nephropathy and to follow the disease
Spot Method
Can you find the presence of microalbumin in a routine chemstrip testing
no
Why is a random urine sample done in the spot method
Tested for the amount of albumin and cratinine present. The amount of albumin present (abnormal) is compared to the amount of creatinine (assumed normal)
What items are checked in a "spot Method"
1. an albumin to creatinine ration
Significance of abnormal protein results
1. increased is pathologic when the level exceeds 150mg/day
What are the functional causes proteinuria
1. r/t changes in glomerular blood flow
These causes of protein urina are usually transient and resolve with time
proteinuria r/t changes in glomerular blood flow or enhanced glomerular permeability
Is the proteinuria with pregnancy usually benign
yes
when is protein uria with pregnancy significant?
with it is in conjunction with hypertension and edema. could be pre-eclampsia
What is orthostatic proteinuria
a benign proteinuria associated with the upright position
What are the organic causes for proteinura
1. prerenal proteinuria: associated with non-renal diseases
name some diseases associated with prerenal proteinuria with non renal diseases
1. multiple myeloma
Define multiple myeloma
malignancy of plasma cells causing production of excess immunoglobulin (Ig) light chains
Causes of renal protein uria
caused by kidney diseases
Renal proteinuria: primary
Glomerulonephritis
Renal proteinuria: induced
Drugs or toxins
Defective tubular reabsorption characterized by increased levels of low molecular weight proteins
Tubular proteinuria
Examples of tubular proteinuria
1. acute or chronic pylelonephritis
Postrenal Proteinuria
Protein from the urinary tract below the level of the kidney parenchyma
Examples of postrenal proteinuria
1. inflammation within the urinary tract
Example of Inflammation within the urinary tract
1. renal pelvis-pyelonephritis