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23 Cards in this Set
- Front
- Back
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Zidovudine (AZT, ZDV)
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Retrovir
A nucleoside reverse transcriptase inhibitor (NRTI) |
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Lamivudine (3TC)
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Epivir
A nucleoside reverse transcriptase inhibitor (NRTI) |
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Emtricitabine (FTC)
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Emtriva
A nucleoside reverse transcriptase inhibitor (NRTI) |
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Stavudine (d4T)
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Zerit
A nucleoside reverse transcriptase inhibitor (NRTI) |
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Didanosine (ddl)
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Videx EC
A nucleoside reverse transcriptase inhibitor (NRTI) |
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Abacavir (ABC)
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Ziagen
A nucleoside reverse transcriptase inhibitor (NRTI) |
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Tenofovir (TDF)
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Viread
A nucleoside reverse transcriptase inhibitor (NRTI) |
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AZT + 3TC
Zidovudine + Lamivudine |
Combivir
BID A nucleoside reverse transcriptase inhibitor (NRTI) |
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AZT + 3TC + ABC
Zidovudine + Lamivudine + Abacavir |
Trizivir
BID A nucleoside reverse transcriptase inhibitor (NRTI) |
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3TC + ABC
Lamivudine + Abacavir |
Epzicom
A nucleoside reverse transcriptase inhibitor (NRTI) |
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FTC + TDF
Emtricitabine + Tenofovir |
Truvada
A nucleoside reverse transcriptase inhibitor (NRTI) |
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Which nucleoside reverse transcriptase inhibitor (NRTI) causes renal dysfunction?
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Tenofovir = Viread
Truvada has tenofovir in it. |
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Which nucleoside reverse transcriptase inhibitor (NRTI) doesn't have to be adjusted for renal dysfunction?
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Ziagen
Abacavir (ABC) |
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Which nucleoside reverse transcriptase inhibitor (NRTI) requires a HLA B5701 test to determine the liklihood of a hypersensitivity reaction?
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Abacavir (ABC)
Ziagen |
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Which 3 drugs have a high liklihood of causing lactic acidosis, pancreatitis, and lipoatrophy?
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Stavudine, Didanosine, and Zidovudine
Combo products: Combivir and Trizivir |
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What can't be taken with d4T?
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AZT (Zidovudine) and Didanosine (Videx EC)
Competes for the same site of action |
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What can't be taken with 3TC?
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Emtricitabine (FTC)
Both are cytosine analogues |
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Which NRTI causes hyperpigmentation of palms?
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Emtricitabine (FTC)
Truvada |
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Which NRTI can't be taken with AZT?
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Stavudine (d4T)
Both are thymidine analogues |
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Which NRTI already has a phosphate on it?
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Tenofovir (TDF)
Viread |
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Is the use of ddl tabs recommended?
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NO!
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Which NRTI causes Headache and BMS (neutropenia or anemia) in 30% of patients?
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Zidovudine (AZT)
Retrovir and Trizivir |
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MoA for the nucleoside reverse transcriptase inhibitors?
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Prematurely terminates DNA elongation by competing with endogenous deoxynucleotides for reverse transcriptase enzyme.
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