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11 Cards in this Set
- Front
- Back
Cell membrane- functions of membrane proteins |
attach cytoskeletal filaments to cell membrane attach cells to extracellular matrix transport molecules in and out of cell acts as receptors for cell signalling enzymatic activity |
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types of endocytic vesicles |
clatrhin coated- 100-150 nm, involves receptor mediated endocytosis uncoated vesicles, 100 nm caveolae, 50 nm, has high binding affinity to cholesterol, common in capillary endothelials phagosomes, large, formed from phagocytosis in phagocytes |
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functions of rER |
have ribosomes attached for protein synthesis |
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functions of sER |
lipid metabolism and detox in hepatocytes steroid hormone production in leydig cells in testis calcium storage and release in muscle cells (as sarcoplasmic reticulum) |
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functions of golgi |
modification + packaging of proteins from rER formation of primary lysosomes recycling of cell membrane through endocytosis |
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mitochondrial DNA is... |
circular, derived solely from mother |
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types of cytoskeleton |
microfilaments (5 nm), intermediate filaments (10 nm) and microtubules (25 nm) |
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functions of microfilaments |
enables cell crawling and cell signaling actin interacts with myosin to generate motile forces |
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functions of intermediate filaments |
organise internal 3D structure of cells, anchors organelles serves as structural components to the nuclear lamina and sarcomeres to provide mechanical support found in some cell-cell/cell-matrix junctions to keep cells intact and together despite stretching |
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types of intermediate filaments |
tonofilaments (keratins) in epithelial cells desmin filaments in muscle cells vimentin in fibroblasts neurofilaments in neurones glial filaments in glial cells nuclear lamina in the nucleus |
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functions of microtubules |
maintains cell structure involved in network formation of endoplasmic reticulum fors axoneme of cilia and flagella for cell movement provides platform for intracelllular transport of organelles, vesicles, chromosomes and pigments |