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34 Cards in this Set

  • Front
  • Back
What are modifiable risks for stroke?
Hypertension
Smoking
Obesity
Elevated serum fibrinogen levels
Diabetes
Sedentary Lifestyles
Contraceptives with high levels of estrogen
Systolic hypertension
Cardiac disease
Atrial fibrillation
Alcohol Abuse
What are non-modifiable risks for stroke?
Age (especially after age 75)
Gender (Slightly higher risk for males)
Race - (higher risk for African-American and Hispanic)
Heredity
List the different types of strokes.
Ischemic (88% of all strokes & includes TIA, thrombosis, embolism, lacunar) and hemorrhagic (12% of all strokes & includes hypertensive and aneurysm).
What are the percentages to the 3 major types of strokes?
50% thrombotic, 38% embolic, 12% hemorrhagic
What causes an ischemic stroke?
Arterial blood supply to the brain is blocked either by atherosclerosis (narrowing of arteries) or clots (moving from the heart as a result of irregular heartbeat/atrial fibrillation, heart attack, or abnormalities of the heart valves).
What is a TIA?
A transient ischemic attack is not really a stroke, but it's a precursor. 35% of all people w/ TIAs will progress to stroke w/in 5 years unless medical intervention occurs. Full recovery expected w/in 24 hours of TIA.

IT IS A BRIEF, FOCAL LOSS OF FUNCTION.
How can TIAs be treated?
Endarterectomy or angioplasty with stinting, blood thinners, monitoring BP & blood flow, diet, and exercise.
What is a thrombosis stroke?
occurs where arteries branch and where plaques may have narrowed the arteries for years. 60% of these strokes occur during sleep.
What's a transitional area of the brain during a thrombosis stroke?
It surrounds the area of anoxia. THERE ARE REVERSIBLE EFFECTS HERE!
What's the intervention for thrombosis?
Medication, specifically, t-PA. Must be given w/in 3 hours post onset of stroke, but most patients wait 24 hours after onset (average is 13 hours).
What is one thing you have to make sure of before you give t-PA?
Make sure the stroke isn't hemorrhagic! t-PA is a major blood thinner and can cause further bleeding. It can also CAUSE a bleed.
What are some other blood thinners?
Heparin, Warfarin, anti-platelet drugs.
What is an embolic stroke?
Stroke of an emboulus that can come from the heart or plaques from any artery. Generally associated with MIs and atrial fibrilation.
With embolic strokes, how often is the middle cerebral artery involved? How often is the posterior cerebral artery involved?
MCA= 80% of the time. PCA=10% of the time.
When can surgery be used to remove the clot from the brain in an embolic stroke?
After the 3 hour window given for the blood thinners.
What is a lacunar stroke?
A stroke of the smaller penetrating "END" arteries. Patients usually make a remarkable recovery.
These frequently occur in people w/ multiple medical diagnoses involving the circulatory system.
Hemorrhagic strokes are caused by what?
AV malformations/ weakness of arterial walls, aneurysms, or head injuries

Bleeding in the brain produces an oval shaped clot that resolves slowly
Treatment of hemorrhagic strokes includes what?
lowering arterial BP to prevent further bleeding & surgery to remove the clot & decrease intracranial pressure
What are the 4 major hemorrhagic hypertensive sites?
Putamenal (most common), thalamic, pontine (most often fatal), cerebellar (ataxia and other cerebellar symptoms)
80% of strokes affect the ____ artery. And it affects the upper extremity more than the lower extremity.
Middle cerebral

Causing contralateral paralysis & sensory loss, hemionopia, & limb-kinetic apraxia
Limb-kinetic apraxia is most commonly in the ______ hemisphere.
left.
In the middle cerebral artery, the dominant hemisphere strokes cause ____, while non-dominant hemisphere strokes cause _____,_____.
Speech deficit; Hemi-neglect, unawareness of distance and midline.
10% of strokes affect affect the ____ artery. It affects the lower extremity more than the upper extremity.
Anterior cerebral

Causing contralateral paralysis and sensory loss, loss of grasp and sucking reflex, lack of spontaneous behavior, motor inattention, perseveration, and amnesia
Anterior cerebral artery stroke leads to lack of...
spontaneous behavior, motor inattention, perseveration, and amnesia.
7% of strokes affect the ____ artery. It affects the contralateral visual field.
Posterior cerebral

cortical blindness (contralateral visual field), memory deficit, ataxia, may have contralateral hemiparesis, involvement of the thalamas can result in contralteral sensory loss
There is a possibility in arm recovery if the patient has a return of arm movement within how much time?
withing first 2 weeks
No grip recovery at 24 days correlates with what kind of arm function?
no arm function at 3 months
What 5 things are responsible for Spontaneous Stroke Recovery?
1. Functional or adaptive recovery
2. recovery of post-stroke edema
3. reperfusion of ischemia
4. diaschisis
5. CNS reorganization
What is Functional or Adaptive Recovery?
Can be defined as neurological or functional (learning to do previously learned tasks)
What kind of stroke tends to be associated with more damage from edema?
Hemorrhages
but recovery is often as dramatic as well
What is reperfusion of ischemia?
Drug therapy and time can allow non-functioning neurons to resume function to save the surrounded area of moderate blod flow that is at risk for ischemia
What is Diaschisis?
The state of low reactivity that occurs after injury to the brain (including stroke) in areas of the brain previously stimulated by this portion of the brain - that is where neuronal connections lie.

Recovery of reactivity in these more distal portions of the brain occur after stroke
What is synaptogenesis?
the formation of new synapses that can occur during CNS re-organization.
Enhanced through motor learning - or practice of new and learned skills
Re-acquiring motor skills requires changes to what?
the undamaged portions of the involved cortex, as well as changes to the undamaged cortex

Practice! But the practice must be challenging enough to force learning