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16 Cards in this Set
- Front
- Back
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Brain consumes how much per min?
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750ml (20%) if CO
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Normal cerebral blood flow per 100g?
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40-50ml
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When does electrical dysfunction occur & irreversible cell death occur?
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10-23ml
<10ml |
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Co2 does what?
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Vasodilates vessels
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how much of glucose in total in the body does the brain utilize?
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25%
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Oxygen & glucose extraction factor?
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50%
10% |
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how much CSF in brain and how much produced per day?
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150ml & 500ml
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2 types of ischaemic stroke?
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Thrombotic & embolic
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2 types of haemorrhagic stroke?
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Aneurism - ballooning of weekend blood vessel (atheroschlorotic plaque & high BP)
Aterovenous malformations - abnormal connections between arteries and veins, increasing the risk of bleeding due to increased pressure |
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Ischaemic penumbra?
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not functioning properly & destined to be irreversibly damaged unless treated, in which case it can regain all its functions.
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Diffusion weighted imaging
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Measures the motion of water flow as diffusion is reduced within minutes of ischaemic stroke
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Why does diffusion decrease in ischaemic stroke?
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Failure of Na K pumps.
Intracellular accumulation of Na and therefore water. Cell swelling Reduced extracellular space Diffusion is hindered. |
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Perfusion weighted imaging
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asseses the tissue at risk by measuring the delivery of blood flow to the capillaries
most commonly through the use of AGENTS. |
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Diffusion - perfusion mismatch
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measures irreversible death of cells and potential death of cells --> used to determine which patients would benefit from thrombolytic treatment.
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T2 weighted imaging of stroke
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measures vasogenic oedema by distinguishing the fat from water.
Measures the water in the brain |
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Brain supplied by which 2 arteries?
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2 vertebral arteries -> Basilar artery
Internal carotid artieries |
