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13 Cards in this Set
- Front
- Back
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Strep organisms involved in osteomyelitis
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S. pyogenes, S. agalactiae, S. pneumoniae
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Morphology
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Chain-arranged, grap-positive cells
Non acid-fast Non spore forming Nonmotile May/May not have capsules |
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Streptococcus viridans
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Alpha-hemolytic
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Biochemistry
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Glucose fermentation test --> lactic acid (pink)
Catalase negative |
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Virulence of S. pyogenes - Hyaluronic acid capsule
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immune evasion
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Virulence of S. pyogenes - Protein G
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Binds to Fc portion of Ab and inhibit phagocytosis
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Virulence of S. pyogenes - Protein F
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Mediates attachement
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Virulence of S. pyogenes - M protein
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Essential virulence factor
Degrades C3b --> escapes phagocytosis |
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How do you differentitate GAS from GBS?
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GAS - bacitracin sesnsitve
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CAMP test
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Characteristic feature of S. agalectiae of forming an arrowhead area of hemolysis at junction of S. aureus (produces sphingomylipase C) and S. agalactiae (produces CAMP factor) --> lysis of erythrocytes
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How do you distinguish S. viridans from another alpha-hemolytic streptococcus?
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S. viridans - Optochin resistance, - bile test
S. pneumorniae - optochin sensitive, + bile test |
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Immunity
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IgA - prevents adhesion
IgG against M-protein - protects against invasion |
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Treatment for Rheumatic Fever
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10 day course of penicillin
Maintenance dose for 5 yrs or til 18 yo Steroids --> carditis Diazepam or haloperidol --> chorea |
