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11 Cards in this Set

  • Front
  • Back

Classification

S. Pyogenes

Beta hemolytic, Group A


Longest chain: S.salivarius


Bacitracin sensitive


PYR positive


Ribose not fermented

Culture

Require carbs with blood/serum


10% CO2 promotes

Serological grouping

Todd Hewitt Broth, Ag extracted using


Lancefield method: HCl


Fuller: formamide


Maxted: Streptomyces albus enzyme


Rantz, Randall: autoclave


Agar gel pptn

Virulence factors

Polysaccharide capsule: anti phagocytic, colonization-biofilm, weak antigen


Cell wall: inside to out-- peptidoglycan, carb, lipoteichoic acid & MTR protein


Fimbria

Hemolysin

O: oxygen labile, cardiotoxic


S: stable, non antigenic

Pyrogenic exotoxin

Scarlatinal toxin


Super antigen


Dick test, Schultz Charlton rxn


Type A mc

Toxins

Streptokinase, hyaluronidase: spread


Streptodornase: serous fluid


Spy Lep: inactivate IL-8

Infections

Pharyngitis: MC


Scarlet fever: sandpaper skin, strawberry tongue, circumoral pallor, HS rxn to toxin


Impetigo: face and leg


Cellulitis: MC org, also Clostr, E.coli, staph


Erysipelas: peau d'orange, cheek


Necrotizing fasciitis


Peurperal sepsis

PYR test

Positive: S.pyogenes, enterococcus


Negative: S.anginosus

Bacitracin

Sensitive: pyogenes


Resistant: anginosus, agalactiae (group B)