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35 Cards in this Set

  • Front
  • Back
What is the morphology and staining of strep?
Gram-positive

Cocci
What type of ultrastructure does Steptococci tend to form?
Chains
Is Steptococci catalse positive or negative?
Negative
Under which oxygen conditions can Steptococci grow?
Both!

Aerobically and anaerobically
Steptococus pyogenes grows in what part of the body?
Skin

Mucous membranes
Steptococcus viridans grows in what part of the body?
Oropharync
Enterobacteriae faecalis grows in what part of the body?
GI tract
GU tract
Steptococcus agalactiae grows in what part of the body?
Lower GI tract
Female GU tract
What organism of the natural reservoir for Steptococci?
Humans
What is does beta hemolysis show up like on a blood agar plate?
Clear zone
What is does alpha hemolysis show up like on a blood agar plate?
Green zone
What is does gamma hemolysis show up like on a blood agar plate?
No hemolysis
What types of streptococci perform beta hemolysis?
Group A (pyogenes)
Group B (agalctiae)
What tyeps of streptococci perform alpha hemolysis?
S. pneumoniae
Enterococci
S. bovis
What bateria is associated with neonatal meningitis?
S. agalctiae
What disease is S. agalctiae associated with?
Neonatal meningitis
What is the diagnostic culturing feature of Enterococcus faecalis?
Grows in high NaCl
What diseases is Enterococcus faecalis associated with?
Endocarditis
UTI
Biliary tract infection
What bacteria can cause endocarditis, UTIs, and biliary tract infections?
Enterococcus faecalis
S. Viridans causes what kinds of diseases?
Dental caries
Endocarditis
Endocarditis secondary to dental caries can be caused by what streptococcus species?
Viridans
Is S. pneumonia bile soluble or insoluble?
Soluble
What are pyogenic/supparative conditions can Group A Streptococcus cause?
Pharyngitis
Impetigo
What pyrogenic conditions can Group A Streptococcus cause?
Scarlet fever
Toxic shock syndrome (TSS)
Puperal fever
Sepsis
What immunologic conditions can Group A Streptococcus cause?
Rheumatic fever
Acute glomerulonephritis
What are the virulence factors of Group A Streptococcus?
C5a peptidase
Fibronectin binding proteins
M-protein
Superantigens!
What is the activity of F protein in this bacteria?
Group A Streptococcus

Binding to respiratory epithelium
What is the activity of the C5a peptidase in this bacteria?
Group A Streptococcus

Cleaving of the C5a; destroying C5a chemotactic activity
What is the activity of M protein in this bacteria?
Group A Streptococcus

Sequestering H factor to block C3 maturation, disrupting the alternative complement pathway
What sort of exterior is on Group A Streptococcus?
Hyaluronic acid capsule
What is the function of the hyaluronic acid capsule in this organism?
Group A Streptococcus

Antiphagocytic
Host mimicry
What is the mechanism for variation in the M protein in this bacteiral species?
Group A Streptococcus

"Slip strand mispairing"
Repeats on the end of genes which cause the formation of different lengths of proteins
What are some digestive enzymes secreted by Group A Streptococcus that help it to spread throughout the tissues?
Hyaluronidase
Streptokinase
DNasess A-D
SPE B - cysteine protease
What is a major determinant if Group A Streptococcus is able to penetrate deep into human tissue?
Capsule!
What are some of the Group A Streptococcus systemic toxins?
SpeA, SpeC
Superantigens