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69 Cards in this Set
- Front
- Back
True or False, a test can be precise but not accurate?
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True
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The proportion of patients with disease that test positive shows the ______ of the test?
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Sensitivity
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The proportion of patients without disease who test negative shows the ______ of the text?
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Specificity
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TP/TP+FN =
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Sensitivity
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FP/FP+TN =
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Specificity
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What is the proportion of all people who test positive who truly have disease?
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TP/FP+TP = Positive Predictive Value = PPV
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All people who test negative and don't truly have disease.
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TN/TN+FN = Negative Predictive Value = NPV
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The further away from _ the more meaningful the ______ ratio is. Which is more meaningful .1, or .4?
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1
likelihood .1 |
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What is a CBC?
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Hematocrit
WBC Hemoglobin Platelet |
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Fill this in >--<.
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HGB
WBC>-------<PLT HCT |
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What cells are included in the WBC differential?
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Neutrophil
Eosinophil Basophil Monocyte Lymphocyte |
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Can a test tell you what kind of lymphocytes you have, T or B?
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No
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Hematocrit can be falsely normal in what?
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Hemorrhage
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MCV increased =
MCV decreased = MCV normal = |
Macrocytic
Microcytic Normocytic |
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MCHC increased =
MCHC decreased = MCHC normal |
Hyperchromic
Hypochromic Normochromic |
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So, if you have a high MCV and a low MCHC how would you title it?
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Macrocytic Hypochromic
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_______, _________, and ____ can give you low MCV.
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Thalassemia, Iron Deficiency, ACD
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RDW measures?
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Cell Size
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What is the best way to find cell size?
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Peripheral Blood Smear
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What is an immature RBC called?
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Reticulocyte
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If you have increased reticulocytes with anemia, this is ?
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Appropriate
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If you have decreased reticulocytes with anemia, this is? and can mean what?
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Inappropriate
Problems with bone marrow |
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Low platelet count is called?
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Thrombocytopenia
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Pseudothrombocytopenia is caused by?
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Platelet Clumping
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A bone marrow biopsy is not contraindicated in?
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Thrombocytopenia
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What is the best way to count platelets?
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Peripheral Blood Smear
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What is the best way to test platelet function?
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Platelet Aggregometry
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The intrinsic pathway is best studied via?
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PTT
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The extrensic pathway is best studied via?
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PT/INR
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What is used to measure warfarin?
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INR
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A deficiency of factor VIII will show up with what?
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Prolonged PTT
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Prothrombin - Thrombin - Fibrinogen - Fibrin - cross linkage. What is the factor studied between fibrin and cross linkage, and what test is used to study this?
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XIII
Urea Clot Solubility Test |
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What is the major extracellular ion?
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Na
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Absence of ADH = ?
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Diabetes Insipidis
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Increased plasma osmolality leads to?
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Increased ADH
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Increased ADH leads to
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Increased water reabsorption
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Increased water reabsorption leads to increased ?
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Urinary osmolality
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Hyponatremia in the presence of a urinary osmolality of <100 = ?
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Diabetes Insipidis
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Hyponatremia leads to decreased plasma osmolality which leads to decreased ___ meaning decreased Free ___ reabsorption leading to decreased _____ osm.
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ADH
H20 Urinary |
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If you have a decreased plasma osmolality but still have ADH in play, what will occur?
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Urine osmolality will be increased above 100
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If you have a urinary osm. of <25 what could this mean?
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Dehydration
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If you are hyponatremic, have a urinary osm >100, and a urinary Na >40 this is considered to be? and caused by what three things?
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Very inappropriate
SIADH Hyperthyroidism Adrenal Insufficiency |
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What are the two adrenal hormones?
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Cortisol and Aldosterone
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If you are hypokalemic, the kidney should do what?
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Excrete less K
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What are the numbers your kidney should be excreting if hypokalemic?
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<15 mEq/L or less than 25-30 mEq/L per day
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What is something that can cause hypokalemia?
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Vomitting
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If you have high aldosterone you should have a high?
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TTKG
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If you have a TTKG of less than _ you have what?
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5
Hypoaldosteronism |
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If you have hypocalcemia, and you have confirmed it, what is the next step?
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Do an intact PTH test.
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What can cause hypercalcemia?
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Hyperparathyroidism
Malignancy PTHrp |
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Normal Na =
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136-144 mEq/L
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Spot urine Na =
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>25
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Plasma K =
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3.5-5.0
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Plasma Cl =
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98-106
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Plasma H2CO3 =
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24
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Total Plasma Ca =
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8.8-10.3
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Ionized Calcium =
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4.5-5.5
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Serum Phosphate =
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2.5-4.5 mg/dL
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Serum Magnesium =
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1.4-2.0
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Normal WBC =
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4400-11000 mm3
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Hematocrit for
Male: Female: |
Male: 46 +/- 4%
Female: 40 +/- 4% |
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Platelet count =
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150k-450k mm3
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Hemoglobin for
Male: Female: |
Male: 15.7
Female: 13.8 |
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MCV =
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88
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MCH
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30.4
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MCHC
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34.4
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RDW
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13.1
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Normal INR
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0.8-1.2
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What are the most prevelant WBCs?
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Lymphocytes and Neutrophils
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