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19 Cards in this Set
- Front
- Back
what are the (4) types of non-small cell lung cancer?
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adenocarcinoma (35% mc)
squamous cell carcinoma (30%) large cell carcinoma (5-10%) bronchoalveolar cell carcinoma |
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what percent of lung CAs are SCLC vs NSCLC?
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small cell lung CA: 25%
non-small cell lung CA: 75% |
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what does squamous cell lung CA look like on CXR?
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centrally located cavitation
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describe the different locations of common lung CAs
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SCLC - central
SCC - central adenocarcinoma - peripheral LCC - peripheral |
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which lung CA has the lowest assn with smoking?
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adenocarcinoma
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how is NSCLC staged?
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primary TNM system
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how is SCLC staged?
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limited:
- confined to chest + supraclavicular nodes - no cervical/axillary nodes extensive: - outside of chest + supraclavicular nodes |
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what are the findings of superior vena cava (SVC) syndrome?
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facial fullness
facial/arm edema dialated veins over ant.chest/arms/face JVD |
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what causes superior vena cava (SVC) syndrome?
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obstruction of the SVC by a mediastinal tumor
(mcc - SCLC) |
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what is Horner's syndrome?
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tumor invasion of cervical sympathetic chain leading to the following features:
- unilateral facial anhidrosis - ptosis (droopy eyelid) - miosis (pupillary contriction) |
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what is Pancoast's tumor?
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apical lung CA involving C8 + T1/2 nerve roots
- shoulder pain/weakness down arm - usually SCC - assd with Horner's (60%) |
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what are the mc sites of metastasis in lung CA?
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"bbagl"
brain bone adrenal glands liver |
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what are the (6) paraneoplastic syndromes seen in lung CA?
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SIADH
ectopic ACTH secretion PTH-like hormone secretion hypertrophic pumonary osteoarthropathy Eaton-Lambert syndrome digital clubbing |
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which (3) paraneoplastic syndromes are assd with SCLC?
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SIADH
ectopic ACTH secretion Eaton-Lambert syndrome |
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which (2) paraneoplastic syndromes are assd with SCC?
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PTH-like hormone secretion
hypertrophic pumonary osteoarthropathy (also adenocarcinoma) |
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what does Eaton-Lambert syndrome look like clinically?
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similar to MG:
- proximal muscle weakness/fatigability - decr DTRs - paresthesias (lower>upper) |
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what CXR findings are assd with a benign lesion?
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no changes over a 2-year period
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describe NSCLC treatment
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surgery is #1 (if no mets)
- radiation important adjunct - chemo is questionable |
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describe SCLC treatment
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chemo is #1
- usually not surgically resectable - radiation for limited stage, not extensive stage |