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19 Cards in this Set

  • Front
  • Back
what are the (4) types of non-small cell lung cancer?
adenocarcinoma (35% mc)
squamous cell carcinoma (30%)
large cell carcinoma (5-10%)
bronchoalveolar cell carcinoma
what percent of lung CAs are SCLC vs NSCLC?
small cell lung CA: 25%
non-small cell lung CA: 75%
what does squamous cell lung CA look like on CXR?
centrally located cavitation
describe the different locations of common lung CAs
SCLC - central
SCC - central

adenocarcinoma - peripheral
LCC - peripheral
which lung CA has the lowest assn with smoking?
adenocarcinoma
how is NSCLC staged?
primary TNM system
how is SCLC staged?
limited:
- confined to chest + supraclavicular nodes
- no cervical/axillary nodes

extensive:
- outside of chest + supraclavicular nodes
what are the findings of superior vena cava (SVC) syndrome?
facial fullness
facial/arm edema
dialated veins over ant.chest/arms/face
JVD
what causes superior vena cava (SVC) syndrome?
obstruction of the SVC by a mediastinal tumor
(mcc - SCLC)
what is Horner's syndrome?
tumor invasion of cervical sympathetic chain leading to the following features:
- unilateral facial anhidrosis
- ptosis (droopy eyelid)
- miosis (pupillary contriction)
what is Pancoast's tumor?
apical lung CA involving C8 + T1/2 nerve roots
- shoulder pain/weakness down arm
- usually SCC
- assd with Horner's (60%)
what are the mc sites of metastasis in lung CA?
"bbagl"

brain
bone
adrenal glands
liver
what are the (6) paraneoplastic syndromes seen in lung CA?
SIADH
ectopic ACTH secretion
PTH-like hormone secretion
hypertrophic pumonary osteoarthropathy
Eaton-Lambert syndrome
digital clubbing
which (3) paraneoplastic syndromes are assd with SCLC?
SIADH
ectopic ACTH secretion
Eaton-Lambert syndrome
which (2) paraneoplastic syndromes are assd with SCC?
PTH-like hormone secretion
hypertrophic pumonary osteoarthropathy (also adenocarcinoma)
what does Eaton-Lambert syndrome look like clinically?
similar to MG:
- proximal muscle weakness/fatigability
- decr DTRs
- paresthesias (lower>upper)
what CXR findings are assd with a benign lesion?
no changes over a 2-year period
describe NSCLC treatment
surgery is #1 (if no mets)
- radiation important adjunct
- chemo is questionable
describe SCLC treatment
chemo is #1
- usually not surgically resectable
- radiation for limited stage, not extensive stage