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23 Cards in this Set

  • Front
  • Back
what is the 60-40-20 rule?
TBW is 60% of body weight

ICF is 40%

ECF is 20%
- interstitial fluid is 15%
- plasma is 5%
[- venous fluid 85%]
[- arterial fluid 15%]
what is normal urine output in adults?
>1.0 mL/kg/hr
what is the 100/50/20 [or 4/2/1] rule?
rule for maintenance fluids:
(0-10) kg - 100/4 mL/kg per day/hr
(10-20) kg - 50/2 mL/kg per day/hr
(20+) kg - 20/1 mL/kg per day/hr
how much should you expect the hct to increase for every liter of fluid deficit?
3% increase
how should blood loss be replaced?
crystalloid at a 3:1 ratio
what is the mc form of maintenance fluid?
D51/2NS
(w/ 20 mEq KCl/L)
when do symptoms of hyponatremia begin?
<120 mEq/L
what is pseudohyponatremia?
incr in plasma solids lowers plasma sodium concentration, but amount of sodium in plasma is normal
what causes hypertonic hyponatremia?
when osmotic substances (glucose, etc) cause an osmotic shift of water out of cells
in the setting of hypovolemic hyponatremia, a urine Na concentration >40 mmol/L is consistant with _____ and 20-40 mmol/L with _____
SIADH

salt wasting nephropathy or hypoaldosteronism
what is the danger of correcting hypotonic hyponatremia too quickly?
increasing Na more than 8 mmol/L in the first 24 hrs can lead to central pontine demyelination
what are the characteristics of central pontine demyelination?
paralysis
dysphagia
dysarthria
what happens when you correct hypernatremia too quickly?
correcting >12 mEq/L per day is assd with cerebral edema

(<8 mEq/L in the first 24 hrs is ideal)
how do you treat hypovolemic hypernatremia?
isotonic NaCl
how do you treat isovolemic hypernatremia?
fluids (and vasopressin for diabetes insipidus)
how do you treat hypervolemic hypernatremia?
diuretics (furosemide) and D5W
what is the major form of calcium in the plasma?
bound to albumin, thus concentration fluctuates w/ albumin concentration

(incr in pH -> incr bound calcium)
how do you calculate free (ionized) calcium in a pt with hypoalbuminemia?
= total calcium - (serum albumin x 0.8)
how does hypomagnesemia effect calcium levels?
it can cause hypocalcemia by decreasing PTH secretion
what does hypo/hyper-calcemia look like on ECG?
hypo = prolonged QT interval
hyper = shortened QT interval
how do you treat symptomatic hypocalcemia?
IV calcium gluconate
(replace magnesium also)
how do you prevent urolithiasis in PTH deficiency?
thiazide diuretics
(lower urinary calcium)
what are the clinical features of hypercalcemia?
stones
bones
groans
psychiatric overtones