• Shuffle
Toggle On
Toggle Off
• Alphabetize
Toggle On
Toggle Off
• Front First
Toggle On
Toggle Off
• Both Sides
Toggle On
Toggle Off
Toggle On
Toggle Off
Front

### How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

Play button

Play button

Progress

1/25

Click to flip

### 25 Cards in this Set

• Front
• Back
 Prevalence Prevalence = Incidence x Duration Sensitivity dz+/test+ divided by total dz+ True positive ratio a/(a+c) Specificity dz-/test- divided by total dz- True Negative ration d/(b+d) Positive Predictive Value dz+/test+ divided by total test+ a/(a+b) Negative Predictive Value dz-/test- divided by total test- d/(c+d) Odds ratio odds of having disease in exposed group divided by odds in unexposed group quantitate how odds change with exposure (a:b)/(c:d) Relative Risk dz risk in exposed group divided by dz risk in unexposed group a/(a+b)/c/(c+d) Attributable risk a/(a+b) - c/(c+d) Confidence interval mean +/- 1.96(SEM) SEM = (std dev)/sqrt(n) Metabolism of FA Acyl CoA prod = -2 ATP Acyl CoA to Acyl CoA and Acetyl CoA = 5 ATP Acetyl CoA in TCA cycle = 12 ATP Cardiac Output O2 consumption/(PaO2-PvO2) Mean Arterial Pressure MAP = CO x TPR MAP = 0.3 Systolic P + 0.6 Diastolic P Stroke Volume CO/HR or ESV-EDV Ejection Fraction SV/EDV Glomerular Filtration Rate GFR = CL|inulin GFR = (Ui x V)/Pi Effective Renal Plasma Flow ERPF = CL|pah ERPF = (Upah x V)/Ppah ERPF is essentially RPF RBF = RPF/(1-Hct) Volume of distribution Vd = amt drug in body/plasma concentration [mL] assume concentration is same in all body compartments Vd for plasma bound drugs Vd = 0.03 L/kg << plasma volume Vd for lipid soluble drugs Vd . 10 L/kg > plasma volume Clearance CL = rate of elim/plasma concentration CL = ke/plasma concentration [mL] hypothetical volume completely cleared of drug per unit time Half-life t1/2 = 0.7(Vd)/CL 3.3 half-lives to get to 90% of Loading dose 6-7 half-lives to get to 100% Loading dose LD = target plasma concentration x Vd/F used to reach Tx dose quickly (antidotes) Maintenance dose MD = target plasma concentration x CL/F Enzyme kinetics: Vo Vo = Vmax[S]/(Km+S) Lineweaver-Burke plot: (1/Vo) (1/Vo) = (Km/Vmax)(1/S) + (1/Vmax)