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212 Cards in this Set

  • Front
  • Back

Classic ECG finding in atrial flutter

sawtooth P waves
Definition of unstable angina
Angina is new, is worsening, or occurs at rest
AntiHTN for a diabetic patient with proteinuria
ACE-I
Beck's triad for cardiac tamponade
Hypotension, distant heart sounds, and JVD
Drugs that slow AV node transmission
B-blockers, digoxin, Ca-channel blockers
Hypercholesterolemia treatment that leads to flushing and pruritis.
Niacin
Treatment for A-fib
Anticoagulation, rate control, cardioversion
Treatment for V-fib
Immediate cardioversion
Autoimmune complication occurring 2-4 weeks post-MI
Dressler's Syndrome: fever, pericarditis and increased ESR
IVDU with JVD and holosystolic murmur at the LSB. Treatment?
Treat existing heart failure and replace the tricuspid valve
Diagnostic test for hypertrophic cardiomyopathy
Echo (thickened LV wall and outflow obstruction)
A fall in systolic BP of > 10 mmHg with inspiration
Pulsus paradoxus
Classic ECG with pericarditis
low-voltage, diffuse ST-segment elevation
Definition of HTN
BP > 140/90 on three separate occasions two weeks apart
8 surgically correctable causes of HTN
1. Renal artery stenosis
2. Coarct of the aorta
3. Pheo
4. Conn's syndrome
5. Cushing's syndrome
6. Unilateral renal parenchymal dz
7. hyperthyroidism
8. hyperparathyroidism
Diagnostic test for hypertrophic cardiomyopathy
Echo (thickened LV wall and outflow obstruction)
A fall in systolic BP of > 10 mmHg with inspiration
Pulsus paradoxus
Classic ECG with pericarditis
low-voltage, diffuse ST-segment elevation
Definition of HTN
BP > 140/90 on three separate occasions two weeks apart
8 surgically correctable causes of HTN
1. Renal artery stenosis
2. Coarct of the aorta
3. Pheo
4. Conn's syndrome
5. Cushing's syndrome
6. Unilateral renal parenchymal dz
7. hyperthyroidism
8. hyperparathyroidism
Diagnostic test for hypertrophic cardiomyopathy
Echo (thickened LV wall and outflow obstruction)
A fall in systolic BP of > 10 mmHg with inspiration
Pulsus paradoxus
Classic ECG with pericarditis
low-voltage, diffuse ST-segment elevation
Definition of HTN
BP > 140/90 on three separate occasions two weeks apart
8 surgically correctable causes of HTN
1. Renal artery stenosis
2. Coarct of the aorta
3. Pheo
4. Conn's syndrome
5. Cushing's syndrome
6. Unilateral renal parenchymal dz
7. hyperthyroidism
8. hyperparathyroidism
Evaluation of a pulsatile abdominal mass and a bruit
Abd U/S and CT
Indications for surgical repair of abdominal aortic aneurysm
>5.5 cm
rapidly enlarging
symptomatic
ruptured
Treatment for acute coronary syndrome
Morphine
O2
sublingual nitroglycerin
ASA
IV B-blockers
heparin
What is metabolic syndrome
abdominal obesity
high triglycerides
low HDL
HTN
insulin resistance
prothrombotic or proinflammatory states
Appropriate diagnostic test for a 50 year old male with angina who can exercise to 85% of maximum predicted HR
Exercise stress treadmill with ECG
Appropriate diagnostic test for a 65 year old woman with LBBB and severe osteoarthritis who has unstable angina
Pharmacologic stress test (dobutamine echo)
Target LDL in a patient with diabetes
< 70
Signs of active ischemia during stress testing
Angina
ST-segment changes on ECG
decreased BP
ECG findings suggesting MI
ST-segment elevation (depression means ischemia)
Flattened T waves
Q waves
A young patient has angina at rest with ST-segment elevation. Cardiac enzymes are nl. Dx?
Prinzmetal's angina
Common symptoms associated with a silent MI
CHF
Shock
Altered mental status
Diagnostic test for PE
V/Q scan
Agent that reverses the effects of heparin
Protamine
The coagulation parameter affected by warfarin
PT
A young patient with a family history of sudden death collapses and dies while exercising
Hypertrophic cardiomyopathy
Endocarditis prophylaxis regimen for oral surgery?
amoxicillin
Endocarditis prophylaxis regimen for GI or GU procedures?
ampicillin and gentamicin before and amox after
6 P's of ischemia due to peripheral vascular disease
Pain
Pallor
Pulselessness
Paralysis
Paresthesia
Poikilothermia
Vichow's triad
Stasis
Hypercoagulability
Endothelial damage
The MCC of HTN in young women? Young men?
Young women: OCPs
Young men: Excessive EtOH
Derm:

stuck-on appearance
seborrheic keratosis
Derm:

red plaques with silvery-white scales and sharp margins
Psoriasis
Derm:

MCC skin cancer; lesion is a pearly-colored papule with a translucent surface and telangectasias
Basal cell CA
Derm:

Honey crusted lesions
Impetigo
Derm:

Febrile pt with a history of DM presents with a red, swollen, painful LE
Cellulitis
Derm:

+ Nikolsky's sign
Pemphigus vulgaris
Derm:

(-) Nikolsky's sign
Bullous pemphigoid
Derm:

55 yo obese pt with dirty, velvety patches on the back of his neck
Acanthosis nigricans; check fasting BG to r/o DM
Derm:

dermatomal distribution
Varicella zoster
Derm:

Flat-topped papules
Lichen planus
Derm:

Iris-like target lesions
Erythema multiforme
Derm:

linear pattern lesion in areas where the skin comes in contact with clothing or jewelry
Contact dermatitis
Derm:

herald patch and Christmas tree pattern
Pityriasis rosea
Derm:

16 yo with an annular patch of alopecia with broken-off stubby hairs
alopecia areata (autoimmune)
Derm:

Pinkish, scaling, flat lesions on the chest and back. KOH prep has speghetti and meatballs appearance
Pityriasis versicolor
Derm:

Four characteristics of a nevus suggestive of melanoma
ABCD
Asymmetry
border irregularity
color variation
large diameter
Derm:

Premalignant lesion from sun exposure that can lead to squamous cell CA
Actinic keratosis
Derm:

Dew drop on a rose petal
lesions of 1' varicella
Derm:

cradle cap
seborrheic dermatitis; treat with antifungals
Derm:

associated with Propionilbacteriun acnes and changes in androgen levels
Acne vulgaris
Derm:

painful, recurrent vesicular eruption of mucocutaneous surfaces
Herpes simplex
Derm:

Inflammation and epithelial thickening of the anogenital area, predominantly in postmenopausal women
Lichen sclerosis
Exophytic nodules on the skin with varying degrees of scaling or ulceration; the second MCC of skin cancer
squamous cell CA
MCC of hypothyroidism
Hashimoto's thyroiditis
Lab findings of Hashimoto's thyroiditis
High TSH, low T4, antimicrosomal antibodies
Exophthalmos, pretibial myedema and low TSH
Grave's disease
MCC of Cushing's Syndrome
iatrogenic sterois administration; second MCC is Cushing's Disease
Pt presents with signs of hypocalcemia, high phosphorous and low PTH
Hypoparathyroidism
"Stones, bones, groans and psychiatric overtones"
Hypercalcemia
Pt c/o headache, weakness, polyuria; PE reveals HTN and tetany. Labs show hypernatremia, hypokalemia, metabolic alkalosis
1' hyperaldosteronism (due to Conn's syndrome or bilateral adrenal hyperplasia)
Pt p/w tachy, wild swings in BP, headache, diaphoresis, AMS, sense of panic
Pheo
Should alpha or beta-antagonists be used first in treating pheo?
alpha-antagonists (phentolamine and phenoxybenzamine)
Pt with a h/o lithium use p/w copius amounts of dilute urine
Nephrogenic DI
Treatment for central DI
Administration of DDAVP to decrease serum osmol and free water restriction
Post-op pt with significant pain p/w hyponatremia and normal volume status
SIADH 2/2 stress
An antidiabetic agent associated with lactic acidosis
Metformin
Pt p/w weakness, n/v, weight loss, and new skin pigmentation. Labs show hyponatremia and hyperkalemia. Treatment?
1' adrenal insufficiency (addison's disease). Treat with replacement glucocorticoids, mineralcorticoids, and IV fluids
Goal Hgb A1c for a patient with DM
<7.0
Treatment of DKA
Fluids, insulin, and aggressive replacement of electrolytes
Why are b-blockers contraindicated in diabetics?
They can mask symptoms of hypoglycemia
Bias introduced into a study when a clinician is aware of the patient's treatment type
Observational bias
Bias introduced when screening detects a disease earlier and thus lengthens the time from diagnosis to death
Lead-time bias
If you want to know if race affects infant mortality rate but most of the variation in infant mortality is predicted by socioeconomic status, then SE status is a_______.
confounding variable
The number of true positives divided by the number of patients with a disease is____.
Sensitivity
Sensitive tests have few false negatives and are used to rule ____ a disease.
Out
PPD reactivity is used as a screening test because most people with TB will have a + PPD. Highly specific or sensitive?
Highly sensitive for TB
Chronic diseases such as SLE-higher prevalence or incidence?
Higher prevalence
Epidemics such as influenza--higher prevalence of incidence?
Incidence
Cross-sectional study--incidence or prevalence?
Prevalence
Cohort study -- incidence of prevalence?
incidence and prevalence
Case control study -- incidence or prevalence?
Neither
Describe a test that consistently gives identical results, but the results are wrong.
high reliability, low validity
Difference between a cohort and a case-control study
Cohort: can be used to calculate relative risk (RR), incidence or odds ratio.

Case control: used to calculate odds ratio
Attributable risk?
(The incidence rate of a disease in exposed) - (the IR of a disease in unexposed)
Relative risk?
The IR of a disease in a population exposed to a particular factor / the IR of those not exposed
Odds ratio?
The likelihood of a disease among individuals exposed to a risk factor compared to those who have not been exposed
Number needed to treat?
1/ (rate in untreated group-rate in treated group)
The MC cancer in men? The MC cause of death from cancer in men?
MC cancer = Prostate

MC cause of death = lung CA
The percentage of cases within one SD of mean? Two? Three?
68%, 95.5%, 99.7%
Birth rate?
Number of live births per 1000 population
Fertility rate?
Number of live births per 1000 women 15-44 years if age
Mortality rate?
Number of deaths per 1000 population
Neonatal mortality?
Number of deathsfrom birth to 28 days per 1000 live births
Postnatal mortality?
Number of deaths from 28 days to 1 year per 1000 live births
Infant mortality?
Number of deaths from birth to 1 year of age per 1000 live births
Fetal mortality?
Number of deaths from 20 weeks' gestation to birth per 1000 total births
Perinatal mortality?
Number of deaths from 20 weeks' gestation to one month of life per 1000 live births
Maternal mortality?
Number of deaths during pregnancy to 90 days postpartum per 100,000 live births
T/F: Once patients sign a statement giving consent, they must continue treatment
False. A pt can change their mind at any time
A 15 yo pregnant girl requires hospitalization. Should her parents be informed?
No. Parental consent is not necessary for the medical treatment of a minor
A doctor refers a patient for an MRI at a facility he/she owns
Conflict of interest
Involuntary psychiatric hospitalization can be undertaken for which three reasons?
danger to self
danger to others
gravely disabled
T/F: Withdrawing life-sustaining care is ethically distinct from withholding sustaining care
False. They are both the same from an ethical standpoint
When can a physician refuse to continue treating a patient on the grounds of futility?
when there is no rationale for treatment, maximal intervention is failing, a given intervention has already failed and treatment will not acheive the goals of care
An eight-year-old child is in a serious accident. she requires an emergent transfusion but her parents are not present.
Treat immediately. Consent is implied in emergency situations
Conditions in which confidentiality must be overridden
Harm to self
Harm to others
certain contagious diseases
elder and Child abuse
Involuntary committment of isolation for medical treatment may be undertaken for what reason?
When treatment noncompliance represents a serious danger to public health (active TB)
A 10 yo child presents in status epilepticus, but her parents refuse treatment on religious grounds
Treat because the disease represents an immediate threat to the child's life. Then seek a court order
A son asks that his mother not be told about her recently discovered cancer
A patient's family cannot require that a doctor withhold information from the patient
Pt presents with sudden onset of sever, diffuse abdominal pain. Exam reveals peritoneal signs and AXR reveals free air under the diaphragm. management?
Emergent laparotomy to repair perforated viscus, likely stomach
The MCC of acute lower GI bleed in patients > 40 yo
Diverticulosis
Diagnostic modality used when U/S is equivocal for cholecystitis
HIDA scan
Sentiel loop on AXR
Acute pancreatitis
Risk factors for cholelithiasis
Fat
forty
Fertile
Female
Flatulent
Inspiratory arrest during palpation of the RUQ
Murphy's sign, seen in acute cholecystitis
Organisms causing diarrhea:

MC organism
Campylobacter
Organisms causing diarrhea:

recent antibiotic use
C. diff
Organisms causing diarrhea:

Camping
Giardia
Organisms causing diarrhea:

Traveler's diarrhea
ETEC
Organisms causing diarrhea:

Church picnics/mayonnaise
S. aureus
Organisms causing diarrhea:

Uncooked hamburgers
E. coli O157:H7
Organisms causing diarrhea:

Fried rice
Bacillus cereus

"Fried rice, you can't B. cereus"
Organisms causing diarrhea:

Poultry/eggs
Salmonella
Organisms causing diarrhea:

Raw seafood
Vibrio, HAV
Organisms causing diarrhea:

AIDS
Isopsora, Cryptosporidium, Mycobacterium avium complex
Organisms causing diarrhea:

Pseudoappendicitis
Yersinia
25 yo Jewish male presents with pain and watery diarrhea after meals. Exam shows fistulas between the bowel and skin and nodular lesions on his tibias.
Crohn's disease
Inflammatory dz of the colon with increased risk of colon cancer
Ulcerative colitis
Extraintestinal manifestations of IBD
Uveitis, ank spond, pyoderma gangrenosum, erythema nodosum, primary sclerosing cholangitis
Medical treatment for IBD
5-aminosalicylic acid agents and steroids during acute exacerbations
Difference between Mallory-Weiss and Boerhaave tears
Mallory-Weiss - superficial tear in the esophageal mucosa

Boerhaave - full-thickness esophageal rupture
Charcot's triad
RUQ pain, jaundice and fever/chills in the setting of ascending cholangitis
Reynold's pentad
Charcot's triad plus shock and mental status changes, with suppurative ascending cholangitis
Medical treatment for hepatic encephalopathy
decreased protein intake, lactulose, neomycin
First step in the management of a patient with acute GI bleed
Establish the ABCs
4 year old child presents with oliguria, petechiae and jaundice following an illness with bloody diarrhea. Most likely diagnosis and cause?
HUS due to E. coli O157:H7
Post-HBV exposure treatment
HBV immunolglobulin
Classic causes of drug-induced hepatitis
TB meds, acetaminophen, tetracycline
40 yo obese female with elevated alk phos, elevate bilirubin, pruritis, dark urine and clay-colored stools
Biliary tract obstruction
Hernia with highest risk of incarceration--indirect, direct, femoral?
femoral hernia
50 yo man with a h/o alcohol abuse presents with boring epigastric pain that radiates to the back and is relieved by sitting forward. Management?
Confirm dx of acute pancreatitis with elevated amylase and lipase. Make the patient NPO and give IV fluids, O2, analgesia and "tincture of time"
4 causes of microcytic anemia
TICS - thalassemia, Iron deficiency, anemia of Chronic disease, and Sideroblastic anemia
An elderly male with hypocromic, microcytic anemia is asymptomatic. Diagnostic test?
Fecal occult blood test and sigmoidoscopy; suspect colorectal CA
Precipitants of hemolytic crisis in patients with G6PD deficiency
Sulfonamides, antimalarial drugs, fava beans
MC inherited cause of hypercoaguability
Factor V leiden
MC inherited hemolytic anemia
Hereditary spherocytosis
Pure RBC aplasia. Dx?
Diamond-Blackfan anemia
Diagnostic test for hereditary spherocytosis
Osmotic fragility test
Anemia associated with absent radii and thumbs, diffuse hyperpigmentation, cafe-au-lait spots, microcephaly and pancytopenia
Fanconi's anemia
Medications and viruses that lead to aplastic anemia
chloramphenicol, sulfonamides, radiation, HIV, chemotherapeutic agents, hepatitis, parvovirus B19, EBV
How to distinguish polycythemia vera from secondary polycythemia
Both have increased hematocrit and RBC mass

PV: normal O2 sat and low EPO levels
TTP pentad?
FAT RN
Fever
Anemia
Thrombocytopenia
Renal dysfunction
Neurologic Abnormalities
HUS triad?
Anemia, thrombocytopenia, plasmaphoresis, corticosteroids, antiplatelet drugs
Treatment for TTP
emergent large-volume plasmaphoresis, corticosteroids, antiplatelet drugs
Treatment for ITP in children
Usually resolves spontaneously; may require IVIG and/or corticosteroids
Which of the following are increased in DIC: fibrin split products, D-dimer, fibrinogen, platelets and hematocrit
fibrin split products and D-dimer are elevated; all others are decreased
8yo boy p/w hemarthrosis and increased PTT with normal PT and bleeding time. Diagnosis and treatment?
Diagnosis: Hemophilia A or B
Tx: desmopressin, FFP, cryoprecipitate
14 yo girl presents with prolonged bleeding after dental surgery and with menses, normal PT, normal or increased PTT and increased bleeding time. Dx? Tx?
Dx: von Willebrand's dz
Tx: desmopressin, FFP or cryoprecipitate
60 yo Af Am male p/w bone pain. Work-up for multiple myeloma might reveal?
monoclonal gammopathy, Bence Jones proteinuria, "punched out lesioins" on xray of the skull and long bones
Reed-Sternberg cells
Hodgkin's lymphoma
10yo boy presents with fever, weight loss and night sweats. Exam shows anterior mediastinal mass. Dx?
Non-hodgkin's lymphoma
Microcytic anemia with low serum iron, low TIBC and normal or increased ferritin?
Anemia of chronic disease
Microcytic anemia with low serum iron, low ferritin and increased TIBC
Iron deficiency anemia
80 yo m with fatigue, lymphadenopathy, splenomegaly and isolated lymphocytosis. suspected dx?
CLL
A late, life-threatening complication of Chronic myelogenous leukemia?
Blast crisis (fever, bone pain, splenomegaly, pancytopenia)
Auer rods on blood smear
Acute myelogenous leukemia (AML)
AML subtype associated with DIC
M3
Electrolyte changes in tumor lysis syndrome
low Ca, high K, high Phospate, high uric acid
Treatment for AML M3
Retinoic acid
50yo m presents with early satiety, splenomegaly and bleeding. Cytogenics show t(9,22). Dx?
CML
Heinz bodies
intracellular inclusions seen in thalassemia, G6PD deficiency, and postsplenectomy
An autosomal-recessive d/o with a defect in the GPIIbIIIa platelet receptor and decreased platelet aggregation
Glanzmann's thrombobasthenia
Virus associated with aplastic anemia in patients with sickle cell anemia
Parvo B19
25yo AfAm male with sickle cell anemia has sudden onset of bone pain. Management of pain crisis?
O2, analgesia, hydration and, if severe, transfusion
A significant cause of mortality in thalassemia patients. Treatment?
Iron overload; tx with deferoxamine
3 MCC of fever of unknown origin
Infection, cancer, and autoimmune disease
4 signs and symptoms of strep pharyngitis?
Fever, pharyngeal erythema, tonsillar exudate, lack of cough
A nonsuppurative complication of strep infection that in not altered by the treatment of the 1' infection
postinfectious glomerulonephritis
Asplenic patients are susceptible to these organisms
encapsulate organisms: Meningitis, pnemococcus,H. influenza, and Klebsiella
The number of bacteria on a clean-catch specimen to dx a UTI?
10^5/mL
Which healthy papulation is susceptible to UTIs?
Pregnant women. Treat aggressively
A patient from California or Arizona who presents with fever, malaise, cough and night sweats. Dx? Tx?
Coccidiodomycosis.

Amphotericin B
Nonpainful chancre
1' syphilis
Blueberry muffin rash is characteristic of what congenital infection?
Rubella
Meningitis in neonates. Causes? Tx?
GBS, E. coli, Listeria

Tx: gentamicin and ampicillin
Meningtitis in infants. Causes? Tx?
Pneumococcus, meningococcus, H. flu

Tx: cefotaxime and vanc
What should always be done prior to a LP?
Check for increased ICP; look for papilledema
DX for the following CSF findings:

low glucose, PMN predominance
Bacterial meningitis
DX for the following CSF findings:

Nl glucose, lymphocytic predominance
Viral meningitis (aseptic)
DX for the following CSF findings:

Numerous RBCs in serial CSF samples
Subarachnoid hemorrhage
DX for the following CSF findings:

increased gamma globulins
MS
p/w pruritic pupule with regional lymphadenopathy and evolved into a black eschar after 7-10. Tx?
cutaneous anthrax.

Tx: Penicillin G or ciprofloxacin
Findings in 3' syphilis
tabes dorsalis, general paresis, gummas, Argyll Robertson pupil, aortits, aortic root aneurysms
Treatment for outpt CAP, pt < 65 yo, otherwise healthy
Macrolide (azithromycin), doxy, or floroquinolone
Treatment for CAP in pt >65 or with a comobidity (COPD, CHF, DM, renal failure)
Macrolide (azithro) or fluoroquinolone; may need 2nd gen cephalosporin or B-lactam
Treatment for CAP requiring hospitalization
extended-spectrum cephalosporin, b-lactam or fluoroquinolone
Treatment for CAP requiring ICU care
Fluoroquinolone or extended-spectrum cephalosporin or B-lactam + macrolide