Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
212 Cards in this Set
- Front
- Back
Classic ECG finding in atrial flutter |
sawtooth P waves
|
|
Definition of unstable angina
|
Angina is new, is worsening, or occurs at rest
|
|
AntiHTN for a diabetic patient with proteinuria
|
ACE-I
|
|
Beck's triad for cardiac tamponade
|
Hypotension, distant heart sounds, and JVD
|
|
Drugs that slow AV node transmission
|
B-blockers, digoxin, Ca-channel blockers
|
|
Hypercholesterolemia treatment that leads to flushing and pruritis.
|
Niacin
|
|
Treatment for A-fib
|
Anticoagulation, rate control, cardioversion
|
|
Treatment for V-fib
|
Immediate cardioversion
|
|
Autoimmune complication occurring 2-4 weeks post-MI
|
Dressler's Syndrome: fever, pericarditis and increased ESR
|
|
IVDU with JVD and holosystolic murmur at the LSB. Treatment?
|
Treat existing heart failure and replace the tricuspid valve
|
|
Diagnostic test for hypertrophic cardiomyopathy
|
Echo (thickened LV wall and outflow obstruction)
|
|
A fall in systolic BP of > 10 mmHg with inspiration
|
Pulsus paradoxus
|
|
Classic ECG with pericarditis
|
low-voltage, diffuse ST-segment elevation
|
|
Definition of HTN
|
BP > 140/90 on three separate occasions two weeks apart
|
|
8 surgically correctable causes of HTN
|
1. Renal artery stenosis
2. Coarct of the aorta 3. Pheo 4. Conn's syndrome 5. Cushing's syndrome 6. Unilateral renal parenchymal dz 7. hyperthyroidism 8. hyperparathyroidism |
|
Diagnostic test for hypertrophic cardiomyopathy
|
Echo (thickened LV wall and outflow obstruction)
|
|
A fall in systolic BP of > 10 mmHg with inspiration
|
Pulsus paradoxus
|
|
Classic ECG with pericarditis
|
low-voltage, diffuse ST-segment elevation
|
|
Definition of HTN
|
BP > 140/90 on three separate occasions two weeks apart
|
|
8 surgically correctable causes of HTN
|
1. Renal artery stenosis
2. Coarct of the aorta 3. Pheo 4. Conn's syndrome 5. Cushing's syndrome 6. Unilateral renal parenchymal dz 7. hyperthyroidism 8. hyperparathyroidism |
|
Diagnostic test for hypertrophic cardiomyopathy
|
Echo (thickened LV wall and outflow obstruction)
|
|
A fall in systolic BP of > 10 mmHg with inspiration
|
Pulsus paradoxus
|
|
Classic ECG with pericarditis
|
low-voltage, diffuse ST-segment elevation
|
|
Definition of HTN
|
BP > 140/90 on three separate occasions two weeks apart
|
|
8 surgically correctable causes of HTN
|
1. Renal artery stenosis
2. Coarct of the aorta 3. Pheo 4. Conn's syndrome 5. Cushing's syndrome 6. Unilateral renal parenchymal dz 7. hyperthyroidism 8. hyperparathyroidism |
|
Evaluation of a pulsatile abdominal mass and a bruit
|
Abd U/S and CT
|
|
Indications for surgical repair of abdominal aortic aneurysm
|
>5.5 cm
rapidly enlarging symptomatic ruptured |
|
Treatment for acute coronary syndrome
|
Morphine
O2 sublingual nitroglycerin ASA IV B-blockers heparin |
|
What is metabolic syndrome
|
abdominal obesity
high triglycerides low HDL HTN insulin resistance prothrombotic or proinflammatory states |
|
Appropriate diagnostic test for a 50 year old male with angina who can exercise to 85% of maximum predicted HR
|
Exercise stress treadmill with ECG
|
|
Appropriate diagnostic test for a 65 year old woman with LBBB and severe osteoarthritis who has unstable angina
|
Pharmacologic stress test (dobutamine echo)
|
|
Target LDL in a patient with diabetes
|
< 70
|
|
Signs of active ischemia during stress testing
|
Angina
ST-segment changes on ECG decreased BP |
|
ECG findings suggesting MI
|
ST-segment elevation (depression means ischemia)
Flattened T waves Q waves |
|
A young patient has angina at rest with ST-segment elevation. Cardiac enzymes are nl. Dx?
|
Prinzmetal's angina
|
|
Common symptoms associated with a silent MI
|
CHF
Shock Altered mental status |
|
Diagnostic test for PE
|
V/Q scan
|
|
Agent that reverses the effects of heparin
|
Protamine
|
|
The coagulation parameter affected by warfarin
|
PT
|
|
A young patient with a family history of sudden death collapses and dies while exercising
|
Hypertrophic cardiomyopathy
|
|
Endocarditis prophylaxis regimen for oral surgery?
|
amoxicillin
|
|
Endocarditis prophylaxis regimen for GI or GU procedures?
|
ampicillin and gentamicin before and amox after
|
|
6 P's of ischemia due to peripheral vascular disease
|
Pain
Pallor Pulselessness Paralysis Paresthesia Poikilothermia |
|
Vichow's triad
|
Stasis
Hypercoagulability Endothelial damage |
|
The MCC of HTN in young women? Young men?
|
Young women: OCPs
Young men: Excessive EtOH |
|
Derm:
stuck-on appearance |
seborrheic keratosis
|
|
Derm:
red plaques with silvery-white scales and sharp margins |
Psoriasis
|
|
Derm:
MCC skin cancer; lesion is a pearly-colored papule with a translucent surface and telangectasias |
Basal cell CA
|
|
Derm:
Honey crusted lesions |
Impetigo
|
|
Derm:
Febrile pt with a history of DM presents with a red, swollen, painful LE |
Cellulitis
|
|
Derm:
+ Nikolsky's sign |
Pemphigus vulgaris
|
|
Derm:
(-) Nikolsky's sign |
Bullous pemphigoid
|
|
Derm:
55 yo obese pt with dirty, velvety patches on the back of his neck |
Acanthosis nigricans; check fasting BG to r/o DM
|
|
Derm:
dermatomal distribution |
Varicella zoster
|
|
Derm:
Flat-topped papules |
Lichen planus
|
|
Derm:
Iris-like target lesions |
Erythema multiforme
|
|
Derm:
linear pattern lesion in areas where the skin comes in contact with clothing or jewelry |
Contact dermatitis
|
|
Derm:
herald patch and Christmas tree pattern |
Pityriasis rosea
|
|
Derm:
16 yo with an annular patch of alopecia with broken-off stubby hairs |
alopecia areata (autoimmune)
|
|
Derm:
Pinkish, scaling, flat lesions on the chest and back. KOH prep has speghetti and meatballs appearance |
Pityriasis versicolor
|
|
Derm:
Four characteristics of a nevus suggestive of melanoma |
ABCD
Asymmetry border irregularity color variation large diameter |
|
Derm:
Premalignant lesion from sun exposure that can lead to squamous cell CA |
Actinic keratosis
|
|
Derm:
Dew drop on a rose petal |
lesions of 1' varicella
|
|
Derm:
cradle cap |
seborrheic dermatitis; treat with antifungals
|
|
Derm:
associated with Propionilbacteriun acnes and changes in androgen levels |
Acne vulgaris
|
|
Derm:
painful, recurrent vesicular eruption of mucocutaneous surfaces |
Herpes simplex
|
|
Derm:
Inflammation and epithelial thickening of the anogenital area, predominantly in postmenopausal women |
Lichen sclerosis
|
|
Exophytic nodules on the skin with varying degrees of scaling or ulceration; the second MCC of skin cancer
|
squamous cell CA
|
|
MCC of hypothyroidism
|
Hashimoto's thyroiditis
|
|
Lab findings of Hashimoto's thyroiditis
|
High TSH, low T4, antimicrosomal antibodies
|
|
Exophthalmos, pretibial myedema and low TSH
|
Grave's disease
|
|
MCC of Cushing's Syndrome
|
iatrogenic sterois administration; second MCC is Cushing's Disease
|
|
Pt presents with signs of hypocalcemia, high phosphorous and low PTH
|
Hypoparathyroidism
|
|
"Stones, bones, groans and psychiatric overtones"
|
Hypercalcemia
|
|
Pt c/o headache, weakness, polyuria; PE reveals HTN and tetany. Labs show hypernatremia, hypokalemia, metabolic alkalosis
|
1' hyperaldosteronism (due to Conn's syndrome or bilateral adrenal hyperplasia)
|
|
Pt p/w tachy, wild swings in BP, headache, diaphoresis, AMS, sense of panic
|
Pheo
|
|
Should alpha or beta-antagonists be used first in treating pheo?
|
alpha-antagonists (phentolamine and phenoxybenzamine)
|
|
Pt with a h/o lithium use p/w copius amounts of dilute urine
|
Nephrogenic DI
|
|
Treatment for central DI
|
Administration of DDAVP to decrease serum osmol and free water restriction
|
|
Post-op pt with significant pain p/w hyponatremia and normal volume status
|
SIADH 2/2 stress
|
|
An antidiabetic agent associated with lactic acidosis
|
Metformin
|
|
Pt p/w weakness, n/v, weight loss, and new skin pigmentation. Labs show hyponatremia and hyperkalemia. Treatment?
|
1' adrenal insufficiency (addison's disease). Treat with replacement glucocorticoids, mineralcorticoids, and IV fluids
|
|
Goal Hgb A1c for a patient with DM
|
<7.0
|
|
Treatment of DKA
|
Fluids, insulin, and aggressive replacement of electrolytes
|
|
Why are b-blockers contraindicated in diabetics?
|
They can mask symptoms of hypoglycemia
|
|
Bias introduced into a study when a clinician is aware of the patient's treatment type
|
Observational bias
|
|
Bias introduced when screening detects a disease earlier and thus lengthens the time from diagnosis to death
|
Lead-time bias
|
|
If you want to know if race affects infant mortality rate but most of the variation in infant mortality is predicted by socioeconomic status, then SE status is a_______.
|
confounding variable
|
|
The number of true positives divided by the number of patients with a disease is____.
|
Sensitivity
|
|
Sensitive tests have few false negatives and are used to rule ____ a disease.
|
Out
|
|
PPD reactivity is used as a screening test because most people with TB will have a + PPD. Highly specific or sensitive?
|
Highly sensitive for TB
|
|
Chronic diseases such as SLE-higher prevalence or incidence?
|
Higher prevalence
|
|
Epidemics such as influenza--higher prevalence of incidence?
|
Incidence
|
|
Cross-sectional study--incidence or prevalence?
|
Prevalence
|
|
Cohort study -- incidence of prevalence?
|
incidence and prevalence
|
|
Case control study -- incidence or prevalence?
|
Neither
|
|
Describe a test that consistently gives identical results, but the results are wrong.
|
high reliability, low validity
|
|
Difference between a cohort and a case-control study
|
Cohort: can be used to calculate relative risk (RR), incidence or odds ratio.
Case control: used to calculate odds ratio |
|
Attributable risk?
|
(The incidence rate of a disease in exposed) - (the IR of a disease in unexposed)
|
|
Relative risk?
|
The IR of a disease in a population exposed to a particular factor / the IR of those not exposed
|
|
Odds ratio?
|
The likelihood of a disease among individuals exposed to a risk factor compared to those who have not been exposed
|
|
Number needed to treat?
|
1/ (rate in untreated group-rate in treated group)
|
|
The MC cancer in men? The MC cause of death from cancer in men?
|
MC cancer = Prostate
MC cause of death = lung CA |
|
The percentage of cases within one SD of mean? Two? Three?
|
68%, 95.5%, 99.7%
|
|
Birth rate?
|
Number of live births per 1000 population
|
|
Fertility rate?
|
Number of live births per 1000 women 15-44 years if age
|
|
Mortality rate?
|
Number of deaths per 1000 population
|
|
Neonatal mortality?
|
Number of deathsfrom birth to 28 days per 1000 live births
|
|
Postnatal mortality?
|
Number of deaths from 28 days to 1 year per 1000 live births
|
|
Infant mortality?
|
Number of deaths from birth to 1 year of age per 1000 live births
|
|
Fetal mortality?
|
Number of deaths from 20 weeks' gestation to birth per 1000 total births
|
|
Perinatal mortality?
|
Number of deaths from 20 weeks' gestation to one month of life per 1000 live births
|
|
Maternal mortality?
|
Number of deaths during pregnancy to 90 days postpartum per 100,000 live births
|
|
T/F: Once patients sign a statement giving consent, they must continue treatment
|
False. A pt can change their mind at any time
|
|
A 15 yo pregnant girl requires hospitalization. Should her parents be informed?
|
No. Parental consent is not necessary for the medical treatment of a minor
|
|
A doctor refers a patient for an MRI at a facility he/she owns
|
Conflict of interest
|
|
Involuntary psychiatric hospitalization can be undertaken for which three reasons?
|
danger to self
danger to others gravely disabled |
|
T/F: Withdrawing life-sustaining care is ethically distinct from withholding sustaining care
|
False. They are both the same from an ethical standpoint
|
|
When can a physician refuse to continue treating a patient on the grounds of futility?
|
when there is no rationale for treatment, maximal intervention is failing, a given intervention has already failed and treatment will not acheive the goals of care
|
|
An eight-year-old child is in a serious accident. she requires an emergent transfusion but her parents are not present.
|
Treat immediately. Consent is implied in emergency situations
|
|
Conditions in which confidentiality must be overridden
|
Harm to self
Harm to others certain contagious diseases elder and Child abuse |
|
Involuntary committment of isolation for medical treatment may be undertaken for what reason?
|
When treatment noncompliance represents a serious danger to public health (active TB)
|
|
A 10 yo child presents in status epilepticus, but her parents refuse treatment on religious grounds
|
Treat because the disease represents an immediate threat to the child's life. Then seek a court order
|
|
A son asks that his mother not be told about her recently discovered cancer
|
A patient's family cannot require that a doctor withhold information from the patient
|
|
Pt presents with sudden onset of sever, diffuse abdominal pain. Exam reveals peritoneal signs and AXR reveals free air under the diaphragm. management?
|
Emergent laparotomy to repair perforated viscus, likely stomach
|
|
The MCC of acute lower GI bleed in patients > 40 yo
|
Diverticulosis
|
|
Diagnostic modality used when U/S is equivocal for cholecystitis
|
HIDA scan
|
|
Sentiel loop on AXR
|
Acute pancreatitis
|
|
Risk factors for cholelithiasis
|
Fat
forty Fertile Female Flatulent |
|
Inspiratory arrest during palpation of the RUQ
|
Murphy's sign, seen in acute cholecystitis
|
|
Organisms causing diarrhea:
MC organism |
Campylobacter
|
|
Organisms causing diarrhea:
recent antibiotic use |
C. diff
|
|
Organisms causing diarrhea:
Camping |
Giardia
|
|
Organisms causing diarrhea:
Traveler's diarrhea |
ETEC
|
|
Organisms causing diarrhea:
Church picnics/mayonnaise |
S. aureus
|
|
Organisms causing diarrhea:
Uncooked hamburgers |
E. coli O157:H7
|
|
Organisms causing diarrhea:
Fried rice |
Bacillus cereus
"Fried rice, you can't B. cereus" |
|
Organisms causing diarrhea:
Poultry/eggs |
Salmonella
|
|
Organisms causing diarrhea:
Raw seafood |
Vibrio, HAV
|
|
Organisms causing diarrhea:
AIDS |
Isopsora, Cryptosporidium, Mycobacterium avium complex
|
|
Organisms causing diarrhea:
Pseudoappendicitis |
Yersinia
|
|
25 yo Jewish male presents with pain and watery diarrhea after meals. Exam shows fistulas between the bowel and skin and nodular lesions on his tibias.
|
Crohn's disease
|
|
Inflammatory dz of the colon with increased risk of colon cancer
|
Ulcerative colitis
|
|
Extraintestinal manifestations of IBD
|
Uveitis, ank spond, pyoderma gangrenosum, erythema nodosum, primary sclerosing cholangitis
|
|
Medical treatment for IBD
|
5-aminosalicylic acid agents and steroids during acute exacerbations
|
|
Difference between Mallory-Weiss and Boerhaave tears
|
Mallory-Weiss - superficial tear in the esophageal mucosa
Boerhaave - full-thickness esophageal rupture |
|
Charcot's triad
|
RUQ pain, jaundice and fever/chills in the setting of ascending cholangitis
|
|
Reynold's pentad
|
Charcot's triad plus shock and mental status changes, with suppurative ascending cholangitis
|
|
Medical treatment for hepatic encephalopathy
|
decreased protein intake, lactulose, neomycin
|
|
First step in the management of a patient with acute GI bleed
|
Establish the ABCs
|
|
4 year old child presents with oliguria, petechiae and jaundice following an illness with bloody diarrhea. Most likely diagnosis and cause?
|
HUS due to E. coli O157:H7
|
|
Post-HBV exposure treatment
|
HBV immunolglobulin
|
|
Classic causes of drug-induced hepatitis
|
TB meds, acetaminophen, tetracycline
|
|
40 yo obese female with elevated alk phos, elevate bilirubin, pruritis, dark urine and clay-colored stools
|
Biliary tract obstruction
|
|
Hernia with highest risk of incarceration--indirect, direct, femoral?
|
femoral hernia
|
|
50 yo man with a h/o alcohol abuse presents with boring epigastric pain that radiates to the back and is relieved by sitting forward. Management?
|
Confirm dx of acute pancreatitis with elevated amylase and lipase. Make the patient NPO and give IV fluids, O2, analgesia and "tincture of time"
|
|
4 causes of microcytic anemia
|
TICS - thalassemia, Iron deficiency, anemia of Chronic disease, and Sideroblastic anemia
|
|
An elderly male with hypocromic, microcytic anemia is asymptomatic. Diagnostic test?
|
Fecal occult blood test and sigmoidoscopy; suspect colorectal CA
|
|
Precipitants of hemolytic crisis in patients with G6PD deficiency
|
Sulfonamides, antimalarial drugs, fava beans
|
|
MC inherited cause of hypercoaguability
|
Factor V leiden
|
|
MC inherited hemolytic anemia
|
Hereditary spherocytosis
|
|
Pure RBC aplasia. Dx?
|
Diamond-Blackfan anemia
|
|
Diagnostic test for hereditary spherocytosis
|
Osmotic fragility test
|
|
Anemia associated with absent radii and thumbs, diffuse hyperpigmentation, cafe-au-lait spots, microcephaly and pancytopenia
|
Fanconi's anemia
|
|
Medications and viruses that lead to aplastic anemia
|
chloramphenicol, sulfonamides, radiation, HIV, chemotherapeutic agents, hepatitis, parvovirus B19, EBV
|
|
How to distinguish polycythemia vera from secondary polycythemia
|
Both have increased hematocrit and RBC mass
PV: normal O2 sat and low EPO levels |
|
TTP pentad?
|
FAT RN
Fever Anemia Thrombocytopenia Renal dysfunction Neurologic Abnormalities |
|
HUS triad?
|
Anemia, thrombocytopenia, plasmaphoresis, corticosteroids, antiplatelet drugs
|
|
Treatment for TTP
|
emergent large-volume plasmaphoresis, corticosteroids, antiplatelet drugs
|
|
Treatment for ITP in children
|
Usually resolves spontaneously; may require IVIG and/or corticosteroids
|
|
Which of the following are increased in DIC: fibrin split products, D-dimer, fibrinogen, platelets and hematocrit
|
fibrin split products and D-dimer are elevated; all others are decreased
|
|
8yo boy p/w hemarthrosis and increased PTT with normal PT and bleeding time. Diagnosis and treatment?
|
Diagnosis: Hemophilia A or B
Tx: desmopressin, FFP, cryoprecipitate |
|
14 yo girl presents with prolonged bleeding after dental surgery and with menses, normal PT, normal or increased PTT and increased bleeding time. Dx? Tx?
|
Dx: von Willebrand's dz
Tx: desmopressin, FFP or cryoprecipitate |
|
60 yo Af Am male p/w bone pain. Work-up for multiple myeloma might reveal?
|
monoclonal gammopathy, Bence Jones proteinuria, "punched out lesioins" on xray of the skull and long bones
|
|
Reed-Sternberg cells
|
Hodgkin's lymphoma
|
|
10yo boy presents with fever, weight loss and night sweats. Exam shows anterior mediastinal mass. Dx?
|
Non-hodgkin's lymphoma
|
|
Microcytic anemia with low serum iron, low TIBC and normal or increased ferritin?
|
Anemia of chronic disease
|
|
Microcytic anemia with low serum iron, low ferritin and increased TIBC
|
Iron deficiency anemia
|
|
80 yo m with fatigue, lymphadenopathy, splenomegaly and isolated lymphocytosis. suspected dx?
|
CLL
|
|
A late, life-threatening complication of Chronic myelogenous leukemia?
|
Blast crisis (fever, bone pain, splenomegaly, pancytopenia)
|
|
Auer rods on blood smear
|
Acute myelogenous leukemia (AML)
|
|
AML subtype associated with DIC
|
M3
|
|
Electrolyte changes in tumor lysis syndrome
|
low Ca, high K, high Phospate, high uric acid
|
|
Treatment for AML M3
|
Retinoic acid
|
|
50yo m presents with early satiety, splenomegaly and bleeding. Cytogenics show t(9,22). Dx?
|
CML
|
|
Heinz bodies
|
intracellular inclusions seen in thalassemia, G6PD deficiency, and postsplenectomy
|
|
An autosomal-recessive d/o with a defect in the GPIIbIIIa platelet receptor and decreased platelet aggregation
|
Glanzmann's thrombobasthenia
|
|
Virus associated with aplastic anemia in patients with sickle cell anemia
|
Parvo B19
|
|
25yo AfAm male with sickle cell anemia has sudden onset of bone pain. Management of pain crisis?
|
O2, analgesia, hydration and, if severe, transfusion
|
|
A significant cause of mortality in thalassemia patients. Treatment?
|
Iron overload; tx with deferoxamine
|
|
3 MCC of fever of unknown origin
|
Infection, cancer, and autoimmune disease
|
|
4 signs and symptoms of strep pharyngitis?
|
Fever, pharyngeal erythema, tonsillar exudate, lack of cough
|
|
A nonsuppurative complication of strep infection that in not altered by the treatment of the 1' infection
|
postinfectious glomerulonephritis
|
|
Asplenic patients are susceptible to these organisms
|
encapsulate organisms: Meningitis, pnemococcus,H. influenza, and Klebsiella
|
|
The number of bacteria on a clean-catch specimen to dx a UTI?
|
10^5/mL
|
|
Which healthy papulation is susceptible to UTIs?
|
Pregnant women. Treat aggressively
|
|
A patient from California or Arizona who presents with fever, malaise, cough and night sweats. Dx? Tx?
|
Coccidiodomycosis.
Amphotericin B |
|
Nonpainful chancre
|
1' syphilis
|
|
Blueberry muffin rash is characteristic of what congenital infection?
|
Rubella
|
|
Meningitis in neonates. Causes? Tx?
|
GBS, E. coli, Listeria
Tx: gentamicin and ampicillin |
|
Meningtitis in infants. Causes? Tx?
|
Pneumococcus, meningococcus, H. flu
Tx: cefotaxime and vanc |
|
What should always be done prior to a LP?
|
Check for increased ICP; look for papilledema
|
|
DX for the following CSF findings:
low glucose, PMN predominance |
Bacterial meningitis
|
|
DX for the following CSF findings:
Nl glucose, lymphocytic predominance |
Viral meningitis (aseptic)
|
|
DX for the following CSF findings:
Numerous RBCs in serial CSF samples |
Subarachnoid hemorrhage
|
|
DX for the following CSF findings:
increased gamma globulins |
MS
|
|
p/w pruritic pupule with regional lymphadenopathy and evolved into a black eschar after 7-10. Tx?
|
cutaneous anthrax.
Tx: Penicillin G or ciprofloxacin |
|
Findings in 3' syphilis
|
tabes dorsalis, general paresis, gummas, Argyll Robertson pupil, aortits, aortic root aneurysms
|
|
Treatment for outpt CAP, pt < 65 yo, otherwise healthy
|
Macrolide (azithromycin), doxy, or floroquinolone
|
|
Treatment for CAP in pt >65 or with a comobidity (COPD, CHF, DM, renal failure)
|
Macrolide (azithro) or fluoroquinolone; may need 2nd gen cephalosporin or B-lactam
|
|
Treatment for CAP requiring hospitalization
|
extended-spectrum cephalosporin, b-lactam or fluoroquinolone
|
|
Treatment for CAP requiring ICU care
|
Fluoroquinolone or extended-spectrum cephalosporin or B-lactam + macrolide
|