Step 2 Hemonc 8

Front 1

MCC of aortic stenosis in a 70 yo px

Back 1

senile or degenerative calcifications

Front 2

what is increased in DIC

Back 2

fibrin split products
D-dimers

Front 3

what is decreased in DIC

Back 3

fibrinogen
platelets
Hct

Front 4

what is the classic presentation of polycythemia vera

Back 4

thrombosis
erythromelalgia
pruritis

Front 5

what is the Rx for polycythemia vera

Back 5

phlebotomy
-induces a desirable iron def anemia

Front 6

what is used in px with polycythemia vera with high risk of thrombosis

Back 6

hydroxyurea

Front 7

what is used in px with polycythemia vera with refractory pruritis or refractory erythrocytosis

Back 7

IFN-a

Front 8

what helps to Dx MM

Back 8

BM biopsy that shows increased plasma cells

UPEP/SPEP with bence jones proteins

Front 9

Dx
px with weight loss, pruritis, night sweats, hepatosplenomegaly, nontender cervical lymphadenopathy

Back 9

hodgkins

Front 10

cell pathology a/w:
EBV

Back 10

burkitts

Front 11

cell pathology a/w:
reed sternberg cell, cervical lymphadenopathy, night sweats

Back 11

hodgkins

Front 12

cell pathology a/w:
bence jones proteins, osteolytic lesions, high Ca

Back 12

MM

Front 13

cell pathology a/w:
translocation 14:18

Back 13

follicular

Front 14

cell pathology a/w:
MC lymphoma in US

Back 14

diffuse large B cell

Front 15

cell pathology a/w:
translocation 8:14

Back 15

burkitts

Front 16

cell pathology a/w:
translocations 9:22

Back 16

philadelphia (CML or ALL)

Front 17

cell pathology a/w:
MC hodgkin lymphoma

Back 17

nodular sclerosing

Front 18

cell pathology a/w:
starry sky pattern due to phagocytosis of apoptotic tumor cells

Back 18

burkitt

Front 19

cell pathology a/w:
high Hct/Hgb, pruritis, burning pain in hands and feet

Back 19

polycythemia vera

Front 20

cell pathology a/w:
white cells with hair like projections and splenomegaly

Back 20

hairy cell

Front 21

cell pathology a/w:
macrocytosis, hypogranular granulocytes with bilobed nuclei

Back 21

myelodysplastic syndrome

Front 22

Rx for CML

Back 22

imatinib

Front 23

leukemia a/w:
MC in children

Back 23

ALL

Front 24

leukemia a/w:
MC in adults

Back 24

CLL

Front 25

leukemia a/w:
philadelphia Chromosome is always present

Back 25

CML

Front 26

leukemia a/w:
smudge cells

Back 26

CLL

Front 27

leukemia a/w:
peripheral blasts are PAS+ and TdT+

Back 27

ALL

Front 28

leukemia a/w:
peripheral blasts are PAS-, myeloperoxidase + and have Auer rods

Back 28

AML

Front 29

leukemia a/w:
pancytopenia in a down syndrome px

Back 29

ALL