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200 Cards in this Set
- Front
- Back
Rx for dermatitis herpetiformis
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Dapsone
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Middle mediastinal masses (6)
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Bronchogenic cysts
Tracheal tumors Pericardial cysts Lymphoma LN enlargement Aortic arch aneurysm |
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Where are neurogenic tumors found in the mediastinum?
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Posterior mediastinum
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Rx for localized Lyme disease in pregnant women
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Amoxicillin
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Rx for disseminated/ late Lyme disease
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IV 3rd generation cephalosporins (ceftriaxone and cefotaxime)
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Who needs the pneumococcal vaccine (2 groups)
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>65 (just once)
<65 w/ chronic medical condition + booster 5 yrs later |
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Common cause of CHF in young pts
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Myocarditis (often from coxsackie B virus)
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Mechanism by which exudative ascites (SAAG <1.1) forms
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Increased capillary permeability
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Mechanism by which transudative ascites (SAAG >1.1) forms
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Portal HTN (increased capillary hydrostatic pressure)
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3 MI settings in which nitrates are not indicated (and why)
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RV infarction
Aortic stenosis Recent phosphodiesterase inhibitor use (b/c SV has decreased, impairing CO, so don't want to reduce preload) |
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MI pt w/ JVD, hypotension, and clear lung fields indicates infarction is where?
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Right ventricular infarction (LV infarction will cause pulmonary edema if it is severe enough to cause hypotension)
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Pt w/ a history of Hodgkin's now w/ hepatomegaly, ascites, and increased JVP
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Constrictive pericarditis from radiation therapy
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3 common causes of respiratory alkalosis (hyperventilation)
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PNA
High altitude Salicylate intoxication |
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Manifestation of galactokinase deficiency
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Cataract development
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3 meds that should be held prior to exercise EKG
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Beta blockers (or others that slow heart)
Anti-ischemics Digoxin |
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New cardiac finding during an MI
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S4 (diastolic dysfunction and stiffened left ventricle --> atrial gallop)
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What pressure is measured at the end of an inspiratory hold in a ventilated pt
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Elastic/ plateau pressure (indicative of pulmonary compliance)
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Four metabolic abnormalities in tymor lysis syndrome
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Hyperkalemia and hyperphosphatemia from cell breakdown
Hypocalcemia (phos binds Ca) Hyperuricemia (from degradation of cellular proteins) |
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Increased PCWP with low CO and high SVR
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Cardiogenic shock
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Rx for needle stick in a HCW not vaccinated for HBV
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HBV vaccine
If source pt is positive for HbsAg, then give HB immune globulin too |
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Most common underlying valve abnormality in a pt w/ infective endocarditis
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MR
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Which joints are affected in SLE and RA?
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MCP and PIP (but SLE is non-deforming)
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Pt w/ ascites and elevated creatinine
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Hepatorenal syndrome
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Cause of renal failure in hepatorenal syndrome
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Liver disease --> systemic vasodilation (2/2 generation of NO in sphlanchnic circulation from portal HTN) --> decreased vacular resistance --> renal hypoperfusion and pre-renal renal failure
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Pt w/ kidney failure and no protein and blood in the urine
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Unlikely to be intrinsic renal disease
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Rx for hepatorenal syndrome
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Midodrine and octreotide
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How to differentiate rotator cuff impingement/ tendonitis from rotator cuff tear?
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Only the former improves w/ a lidocaine injection
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Upper arm numbness, weakness, and swelling w/ weakened radial pulse
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Thoracic outlet syndrome (compression of subclavian vessels and lower trunk of brachial plexus)
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Throbbing pain in distal phalanx which is swollen, soft, and tender w/ non-purulent vesicles
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Herpetic whitlow (HSV)
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Electron microscopy findings in Alport's syndrome
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Alternating areas of thinned and thickened capillary loops w/ splitting of the GBM
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4 categories of asthma
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Intermittent (<2x/wk)
Mild persistent (symptoms >2x/wk but not daily, 3-4 awakenings/mo) Moderate persistent (daily symptoms, weekly awakenings, FEV1 60-80% predicted) Severe persistent (symptoms throughout day, frequent awakenings, FEV1 <60% predicted) |
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Meds for each of the 4 classes of asthma
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Intermittent: short-acting beta-2 agonist (albuterol) inhaler
Mild persistent (add inhaled corticosteroids) Moderate persistent (add long-acting inhaled beta-2 agonist inhaler) Severe persistent (add oral prednisone) |
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Cause of hypocalcemia/
hypophosphatemia in an alcoholic |
Malabsorption of Vitamin D 2/2 chronic pancreatitis
(acute pancreatitis can do the same thing) |
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Three causes of avascular (aseptic) necrosis of the femoral head
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Chronid steroids
Alcoholism Hemoglobinopathy |
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Rx for pts who have had an episode of rheumatic fever
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Abx prophylaxis w/ penicillin to prevent further attacks (which can worsen valvular function)
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Management of CIN II/III after LEEP
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Pap smear +/- colpo q 6 mo until 3 negative tests obtained; then annual Paps until 3 negative tests; then q 3 yrs (like everyone else)
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Rx for first uncomplicated kidney stone
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CT, NSAIDs, fluids >2L/day
(don't need 24 hr urine collection until have recurrent stones) |
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Soap bubble appearance on xray of distal epiphysis of femur
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Giant cell tumor of bone
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How to define a saline-responsive metabolic alkalosis, typical causes, and treatment
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Urine chloride <20
Hypovolemia or GI proton loss (e.g. vomiting) IV saline |
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Polyarthralgia, tenosynovitis, and painless vesiculopustular skin lesions
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Disseminated gonococcal infection
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Mechanism of warfarin-induced skin necrosis within a few days of starting treatment
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Protein C deficiency
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Immunocompromised pt w/ cultures growing gram-positive branching rod, partially acid fast
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Nocardia asteroides
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Rx for nocardiosis
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Bactrim
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3 ways to distinguish actinomyces and nocardia infections
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Actinomyces is anaerobic (nocardia is aerobic) and is more likely to cause cervicofacial disease and sinus tracts and may have sulfur granules
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Rx for actinomyces infection
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Penicillin G
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JAK2 mutation may be seen in
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Polycythemia vera
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Most common cause of isolated right-sided heart failure
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Pulmonary disease (cor pulmonale)
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Pathophys of hepatic encephalopathy (4)
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Accumulation of ammonia, production of false neurotransmitters, increased CNS sensitivity to inhibitory neurotransmitters, and zinc deficiency
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First step in aortic dissection pt w/ HTN
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Antihypertensive management (TEE is best diagnostic study, but comes afterward)
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Asymmetric oligoarthritis, urethritis, and mouth ulcers
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Reactive arthritis (Reiter syndrome)
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LAP, O2 sat, and EPO level in polycythemia vera
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Elevated
Normal Low |
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IVDU w/ pleuritic pain and cavitating lung nodules on CXR
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Septic emboli from tricuspid valve endocarditis (most often from S. aureus)
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Criteria for MGUS diagnosis
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Asymptomatic elevation of monoclonal protein <3
No anemia, lytic bone lesiosn, hypercalcemia, renal insufficiency, or anything else to suggest multiple myeloma |
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Why is aggressive diuresis not recommended for treatment of ascites?
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Risk of hepatorenal syndrome
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Most common cause of death in pts with acute MI
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Complex ventricular arrhythmia (partial block --> re-entrant arrhythmia, e.g. v fib)
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Elderly pt w/ tense bullae and urticarial plaques (+ pruritus)
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Bullous pemphigoid
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Pathophys of bullous pemphigoid
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IgG and C3 deposits at dermal-epidermal junction
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Tea and toast diet is associated w/ what dietary deficiency?
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Folic acid --> anemia
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Mechanism of a transudative pleural effusion
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Either increased hydrostatic pressure (e.g. CHF) or decreased oncotic pressure (e.g. liver failure)
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Common side effect of dihydropyridine Ca-channel antagonists (e.g. amlodipine)
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Peripheral edema
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Immigrant w/ high grade periodic fever, anemia, and splenomegaly
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Malaria
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Risk with HIT
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Paradoxically it is thrombogenic, so at risk for arterial and venous clots
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3 causes of postchole pain
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Sphincter of Oddi syfunction
CBD stone Functional pain |
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Risk factors for esophageal cancer: SCC vs. adenocarcinoma
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Squamous: smoking/alcohol
Adeno: GERD/ Barrett's |
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HTN, mild hypernatremia, hypokalemia, metabolic alkalosis
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Primary hyperaldosteronism/ Conn's syndrome (excess aldosterone promotes reabsorption of sodium and secretion of K+ and H+ ions)
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Renin level in Conn's syndrome
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Decreased due to feedback inhibition from high aldosterone
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Management of HTN in a pt on OCPs
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D/c OCPs
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Short-term bloody diarrhea w/o travel history or fever
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EHEC O157:H7
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Pathophys of GVHD
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Recognition of host major and minor HLA antigens by donor T cells --> cell-mediated immune response
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Complication of temporal arteritis (other than vision loss)
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Aortic aneurysm
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Psoriatic arthritis most commonly involves which joints?
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DIP joints
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Potential complication of aortic dissection that can cause hypotension
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Cardiac tamponade
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Persistent nasal blockage and episodes of bronchoconstriction in a pt w/ chronic analgesic use for headaches
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Aspirin sensitivity syndrome
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Pathophys of aspirin sensitivity syndrome
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Pseudo-allergic reaction: exaggerated release of vasoactive and inflammatory mediators
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Rx for aspirin sensitivity syndrome
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Leukotriene inhibitors, topical steroids
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FEV1/FVC ratio in obstructive vs. restrictive disease
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Obstructive: <80%
Restrictive: >80% |
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Frequent complication of nephrotic syndrome
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Hypercoagulability (multifactorial), most commonly leading to renal vein thrombosis (esp w/ membranous glomerulopathy)
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5 other complications of nephrotic syndrome
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Protein malnutrition
Microcytic hypochromic anemia (transferrin loss) Vita D deficiency (loss of cholecalciferol-binding protein) Decrease thyroxine (loss of TBG) Increased susceptibility to infection |
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Chronology of abdominal pain in acute appendicitis
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Visceral followed by somatic pain
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Rx for acute bleeding in pts with liver failure
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FFP (has all the clotting factors)
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What is the water bottle sign on CXR indicative of?
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Pericardial effusion
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Characteristics of a simple renal cyst that requires no follow-up
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Thin walls, no solid component, no enhancement
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4 worrisome findings of a renal mass
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Multilocular
Thickened, irregular walls Thickened septae w/in the mass Contrast enhancement |
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How to diagnose allergic rhinitis
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Nasal cytology (for eosinophils; neutrophils would indictae infectious cause)
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Other causes of nasal eosinophilia (besides allergic rhintiis)
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Nasal polyposis (including aspiring sensitivity) and non-allergic rhinitis
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DLCO and pulmonary compliance in interstitial lung disease
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Both decreased
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Elderly pt w/ asymptomatic femoral bowing on xray
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Paget's disease
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Pathophys of Paget's
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Osteoclast hyperfunction --> mosaic pattern of lamellar bone
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Why do pts with obesity hypoventilation syndrome have respiratory acidosis?
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Decreaesd chest wall compliance --> increased work of breathing
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HIV pt taking all his meds and prophy drugs with hyperkalemia
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Likely 2/2 trimethoprim
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NPO postop pt who is bleeding is most likely due to
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Vitamin K deficiency (so give FFP)
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IBD w/ crypt abscess is most likely due to
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Ulcerative colitis
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Diarrhea w/ intestinal villous atrophy is likely due to
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Celiac sprue
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Afebrile pt w/ new-onset blood-tinged sputum, cold symptoms, and normal PEX
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Likely acute bronchitis (viral); just observe
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Pneumonia w/ GI symptoms and hyponatremia
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Legionella
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Pathophys of Baker cysts
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Excessive fluid produced by inflamed synovium (e.g. in RA, OA, and cartilage tears) that accumulates in the popliteal bursa
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5 most effective lifestyle ways to lower BP, in order
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Weight loss
DASH diet Dietary sodium restriction Exercise Decrease alcohol intake |
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4 causes of pulsus paradoxus (abnormally large drop in SBP w/ inspiration)
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Tamponade
Pericardial effusion Tension pneumo Severe asthma |
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Rx for torsades de pointes
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Magnesium sulfate
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Pstop pt with syncope/ hypotension, JVD, and RBBB
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Massive PE --> cardiogenic shock
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Pt w/ hyperactive DTRs after multiple blood transfusions
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Hypocalcemia from citrate binding
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Acid-base disturbance in primary adrenal failure
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Normal AG hyperkalemic, hyponatremic metabolic acidosis (from aldosterone deficiency)
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Pathogens associated w/ acute epididymitis
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Younger pts w/ urethritis as well: chlamydia or neisseria
Older pts w/ UTI as well: E. coli |
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Best way to improve survival in COP
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Supplemental O2 therapy
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Rx for an intubated pt who is persistently hypoxemic despite high FiO2 settings
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Add PEEP to prevent alveolar collapse
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Cause of hypoxia in pts with PNA
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Alveolar and interstitial inflammation --> areas of V/Q mismatch --> increased A-a oxygen gradient
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Potential cause of persistent/recurrent chalazion
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Meibomian gland carcinoma (sebaceous carcinoma), so needs biopsy
|
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Rx for renal artery stenosis 2/2 fibromuscular dysplasia
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Angioplasty w/ stent placement
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Which live vaccine can be given to HIV pts?
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MMR, if CD4 >200 (b/c measles is life-threatening in HIV pts)
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IBD w/ noncaseating granulomas
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Crohn's disease
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Lymphoblasts in ALL stain
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PAS-positive
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Palpable purpura, proteinuria, hematuria
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Mixed cryoglobulinemia
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Many pts w/ mixed cryoglobulinemia also have what infection?
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HCV
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Systemic vasculitis, upper and lower airway granulomatous inflammation, and glomerulonephritis
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Granulomatosis w/ polyangitis (Wegener's)
|
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Rx for Wegener's
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Cyclophosphamide
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Definitive and intermediate hosts for hydatid cysts (and the pathogen that causes them)
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Sheep and dogs, respectively
Echinococcosis |
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What is anasarca?
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Generalized edema (pulm, ascites, swollen extremities)
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Size cut-off for worrisome LN
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>2cm
|
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Asymmetric polyarthritis before or after purulent monoarthritis
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Gonococcal septic arthritis
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Painless visual loss w/ optic disk swelling, retinal hemorrhage, dilated veins, and cotton wool spots
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CRVO
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Painless visual loss w/ optic disc pallor, cherry red fovea, and boxcar segmentation of blood in the retinal veins
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CRAO
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Temporary visual loss
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Amaurosis fugax
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Acid-base abnormality in PE
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Respiratory alkalosis (due to hyperventilation)
|
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Cholangiography showing beading (dilation) of the intrahepatic and/or extrahepatic bile ducts
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PSC
|
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Recent onset confusion, fever, muscle rigidity, and diaphoresis
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Neuroleptic malignant syndrome (drug-induced idiosyncratic reaction)
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Pathophys of anemia in SLE
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Warm autoimmune hemolysis
|
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Pathophys of SLE-associated thrombocytopenia and neutropenia
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Antibody mediated destruction
|
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Rx for bartonella
|
Oral azithromycin
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Symmetric duskiness and coolness of all fingertips/ toes in an ICU pt
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Norepinephrine-induced vasospasm --> ischemia
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Best neuromuscular blocker for a pt with both liver and kidney failure
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Atracurium (degrades spontaneously in plasma)
|
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Rx for tick on skin
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Remove (ideally within 24hrs) by grabbing mouth w/ tweezers
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Cause of presbyopia
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Decreased lens elasticity, so can't focus on near objects
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Anion gap metabolic acidosis with optic disc hyperemia
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Methanol ingestion
|
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Best Rx for cancer-induced cachexia (no appetite)
|
Progestin agents
|
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Pruritic vesicles and pustules in gray wavy runs over finger webs, heels of palms, and wrist creases + papules over nipples, areola, scrotum, penis
|
Scabies
|
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Difficulty swallowing, lots of dental caries, enlarged/firm salivary glands
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Sjogren Syndrome (lack normal amount of saliva; lymhocytic infiltrate of saliva glands)
|
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Diabetes, hepatomegaly, arthropathy
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Hemochromatosis
|
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Pain over the anteromedial tibia just below the joint line, often worst at night (when touching)
|
Anserine bursitis
|
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Young male with morning pain in his hands
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RA
|
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How to differentiate the thickening in hypertrophic vs. restrictive cardiomyopathy
|
Hypertrophic: septum is thickest
Restrictive: symmetrical thickness |
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Reversible cause of restrictive cardiomyopathy
|
Hemochromatosis
|
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Atypical PNA with a skin rash (erythema multiforme: dusky red target shaped lesions)
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Mycoplasma
|
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Most common complication of inhaled corticosteroids
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Oropharyngeal candidiasis (oral thrush)
|
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Rx for CML and its mechanism
|
Imatinib (Gleevec): tyrosine kinase inhibitor that binds the ATP binding site of BCR-ABL, preventing conformation change to its active form
|
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Mono symptoms + rash and diarrhea
|
HIV
|
|
Rx for Zenker's diverticulum
|
Excision, usually with cricopharyngeal myotomy
|
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Rx for sphincter of Oddi dysfunction after chole
|
ERCP with sphincterotomy
|
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Pathophys of ARDS
|
Inflammatory mediators from tissue injury damage the alveoli --> alveolar capillary permeability --> fluid leaks into alveoli, causing pulmonary edema
|
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Rx for ARDS
|
Mechanical ventilation w/ low tidal volumes and PEEP (may require up to 15 cm H2O of PEEP)
|
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Pathophys of statin induced myopathy
|
Inhibiting HMG CoA also inhibits mevalonate production, which is also used in production of CoQ10 --> myopathy
|
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Tobacco induced white granular texture on mouth
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Leukoplakia
|
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Risk of leukoplakia
|
Transformation into squamous cell carcinoma
|
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Vaccines for HIV pts
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Td booster, influenza, S. pneumo, hep A (if pt is MSM), and hep B
|
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Area w/ dullness to percussion and increased fremitus (but normal breath sounds)
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Likely consolidation/ PNA
|
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Exam findings with pneumothorax (air in pleural space)
|
Decreased breath sounds, hyperresonance to percussion, decreased fremitus, transmitted voice sounds
|
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Exam findings w/ fluid in pleural space (effusion)
|
Blocks sound transmission so dull to percussion, decreased breath sounds, decreased fremitus
|
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Abd pain, diarrhea, malabsorption w/ steatorrhea + migratory polyarthropathy, chronic cough, valvular regurgitation
|
Whipple's disease
|
|
Biopsy in Whipple's disease
|
PAS-positive material in lamina propria of small intestine
|
|
Swollen, pale arm after placement of subclavian line
|
Subclavian vein thrombosis
|
|
Rx for subclavian vein thrombosis
|
Remove central line first! Then duplex, may need anticoagulation
|
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Management of solid testicular mass
|
US; if suggestive, radical orchiectomy (don't biopsy! Could spill cancer cells, will diagnose after excision)
|
|
Bilateral tearing, intense itching, hyperemia, tearing, and conjunctival/eyelid edema
|
Allergic conjunctivitis
|
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Cause of aspiration PNA in demented pt
|
Impaired epiglottic reflex/ swallowing
|
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Rx for hepatic hydrothorax (1st, 2nd, and 3rd line)
|
Therapeutic thoracentesis + diuretics/ salt restricted diet
TIPS Liver transplant |
|
Rx for hepatorenal syndrome
|
Liver transplant
|
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Definition of hepatorenal syndrome
|
Cirrhosis with renal failure that doesn't respond to volume resuscitation
|
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Hyperglycemia, weight loss, scaly papules on face
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Glucagonoma triad
|
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HIV pt w/ bright red, firm, friable, exophytic nodules
|
Bacillary angiomatosis
|
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Pathogen causing bacillary angiomatosis
|
Bartonella (gram negative)
|
|
Rx for bacillary angiomatosis
|
Oral erythromycin
|
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HIV pt w/ RUL cavity growing partially acid-fast, filamentous, branching rods
|
Nocardia
|
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Rx for Nocardia
|
Bactrim
|
|
Criteria for long term O2 therapy in COPD pts (3)
|
PaO2 <55 or SaO2 <88%
Cor pulmonale, evidence of pulm HTN, or hematocrit <55% change the cut-offs to 59 and 89% Nocturnal hypoxia |
|
HIV pt w/ LAD, pancytopenia, hepatosplenomegaly, palatal ulcers, and interstitial pneumonitis
|
Disseminated histoplasmosis
|
|
Of histo, blasto, and coccidio, which is unlikely to infect i/c hosts?
|
Blasto
|
|
Red eye w/ leukocytes in anterior chamber
|
Anterior uveitis
|
|
Young pt w/ chest pain and short systolic murmur at apex that disappears w/ squatting
|
Mitral valve prolapse (squatting increases preload, which decreases murmur)
No explanation for why MVP pts have chest pain |
|
SIADH is most commonly associated w/ what kind of lung cancer?
|
Small cell carcinoma
|
|
What to tell pts who are starting warfarin
|
Many foods have vitamin K and will decrease its efficacy
Many meds will decrease its efficacy as a side effect |
|
Mechanism of varencicline
|
Partial agonist of nicotinic acetylcholine receptor
|
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Post eye operation, pt w/ pain, decreased visual acuity, swollen eyelids and conjunctiva, corneal edema and infection
|
Postop endophthalmitis (infection w/in vitreous of eye)
|
|
Rx for postop endophthalmitis
|
Intravitreal antibiotic injection or vitrectomy
|
|
Dx and management of urinary urgency, hesitancy, and nocturia w/ smoothly enlarged prostate w/ elevated creatinine
|
BPH
Need abd US to r/o hydronephrosis (if so, need Foley and likely a TURP) |
|
Pt with diverticulitis who isn't improving on Abx
|
CT scan to r/o complications like abscess or fistula
|
|
Drugs to avoid in HOCM
|
Nitrates (or anything that reduces preload: worsens obstruction)
|
|
2 cancers tamoxifen places pts at risk of
|
Uterine endometrial cancer and sarcoma
|
|
Other risk of tamoxifen
|
Venous thrombosis
|
|
What do leukocyte esterase and nitrates indicate
|
LE: pyuria
Nitrates: enterobacteriaceae |
|
Non-tender, indurated neck mass which is draining fluid w/ Gram positive, branching bacteria
|
Actinomyces
|
|
Rx for Actinomyces
|
High dose IV penicillin for 6-12 wks
|
|
Dev't of fever, hemolysis and DIC 30 min after blood transfusion
|
Acute hemolytic transfusion reaction from ABO or minor antigen mismatched blood
|
|
Mono presentation w/ negative heterophile Ab test
|
Test may be negative early in illness; should repeat
|
|
Best test for lactose intolerance
|
Hydrogen breath test (increase in hydrogen after ingestion of lactose indicates bacterial carb metabolism, i.e. positive test)
|
|
Stool tests in lactose intolerance (3)
|
Low pH, increased osmotic gap, positive test for reducing substances
|
|
Which type of ulcers are worse on an empty stomach and why?
|
Duodenal (unopposed acidic fluid empties into duodenum)
|
|
Rx for duodenal ulcer
|
Abx (90% have H pylori) and PPIs
|
|
3 classes of drugs that should be taken w/ folic acid
|
Anti-epileptics, MTX, TMP
|
|
Axillary freckling and cafe au lait spots
|
Neurofibromatosis, type 1
|
|
Ophtho risk w/ neurofibromatosis
|
Optic glioma
|
|
Presentation of optic glioma
|
Slowly progressive unilateral vision loss, dyschromatopsia, exophthalmos
|