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200 Cards in this Set

  • Front
  • Back
Rx for dermatitis herpetiformis
Dapsone
Middle mediastinal masses (6)
Bronchogenic cysts
Tracheal tumors
Pericardial cysts
Lymphoma
LN enlargement
Aortic arch aneurysm
Where are neurogenic tumors found in the mediastinum?
Posterior mediastinum
Rx for localized Lyme disease in pregnant women
Amoxicillin
Rx for disseminated/ late Lyme disease
IV 3rd generation cephalosporins (ceftriaxone and cefotaxime)
Who needs the pneumococcal vaccine (2 groups)
>65 (just once)
<65 w/ chronic medical condition + booster 5 yrs later
Common cause of CHF in young pts
Myocarditis (often from coxsackie B virus)
Mechanism by which exudative ascites (SAAG <1.1) forms
Increased capillary permeability
Mechanism by which transudative ascites (SAAG >1.1) forms
Portal HTN (increased capillary hydrostatic pressure)
3 MI settings in which nitrates are not indicated (and why)
RV infarction
Aortic stenosis
Recent phosphodiesterase inhibitor use

(b/c SV has decreased, impairing CO, so don't want to reduce preload)
MI pt w/ JVD, hypotension, and clear lung fields indicates infarction is where?
Right ventricular infarction (LV infarction will cause pulmonary edema if it is severe enough to cause hypotension)
Pt w/ a history of Hodgkin's now w/ hepatomegaly, ascites, and increased JVP
Constrictive pericarditis from radiation therapy
3 common causes of respiratory alkalosis (hyperventilation)
PNA
High altitude
Salicylate intoxication
Manifestation of galactokinase deficiency
Cataract development
3 meds that should be held prior to exercise EKG
Beta blockers (or others that slow heart)

Anti-ischemics

Digoxin
New cardiac finding during an MI
S4 (diastolic dysfunction and stiffened left ventricle --> atrial gallop)
What pressure is measured at the end of an inspiratory hold in a ventilated pt
Elastic/ plateau pressure (indicative of pulmonary compliance)
Four metabolic abnormalities in tymor lysis syndrome
Hyperkalemia and hyperphosphatemia from cell breakdown

Hypocalcemia (phos binds Ca)

Hyperuricemia (from degradation of cellular proteins)
Increased PCWP with low CO and high SVR
Cardiogenic shock
Rx for needle stick in a HCW not vaccinated for HBV
HBV vaccine
If source pt is positive for HbsAg, then give HB immune globulin too
Most common underlying valve abnormality in a pt w/ infective endocarditis
MR
Which joints are affected in SLE and RA?
MCP and PIP (but SLE is non-deforming)
Pt w/ ascites and elevated creatinine
Hepatorenal syndrome
Cause of renal failure in hepatorenal syndrome
Liver disease --> systemic vasodilation (2/2 generation of NO in sphlanchnic circulation from portal HTN) --> decreased vacular resistance --> renal hypoperfusion and pre-renal renal failure
Pt w/ kidney failure and no protein and blood in the urine
Unlikely to be intrinsic renal disease
Rx for hepatorenal syndrome
Midodrine and octreotide
How to differentiate rotator cuff impingement/ tendonitis from rotator cuff tear?
Only the former improves w/ a lidocaine injection
Upper arm numbness, weakness, and swelling w/ weakened radial pulse
Thoracic outlet syndrome (compression of subclavian vessels and lower trunk of brachial plexus)
Throbbing pain in distal phalanx which is swollen, soft, and tender w/ non-purulent vesicles
Herpetic whitlow (HSV)
Electron microscopy findings in Alport's syndrome
Alternating areas of thinned and thickened capillary loops w/ splitting of the GBM
4 categories of asthma
Intermittent (<2x/wk)

Mild persistent (symptoms >2x/wk but not daily, 3-4 awakenings/mo)

Moderate persistent (daily symptoms, weekly awakenings, FEV1 60-80% predicted)

Severe persistent (symptoms throughout day, frequent awakenings, FEV1 <60% predicted)
Meds for each of the 4 classes of asthma
Intermittent: short-acting beta-2 agonist (albuterol) inhaler

Mild persistent (add inhaled corticosteroids)

Moderate persistent (add long-acting inhaled beta-2 agonist inhaler)

Severe persistent (add oral prednisone)
Cause of hypocalcemia/
hypophosphatemia in an alcoholic
Malabsorption of Vitamin D 2/2 chronic pancreatitis

(acute pancreatitis can do the same thing)
Three causes of avascular (aseptic) necrosis of the femoral head
Chronid steroids
Alcoholism
Hemoglobinopathy
Rx for pts who have had an episode of rheumatic fever
Abx prophylaxis w/ penicillin to prevent further attacks (which can worsen valvular function)
Management of CIN II/III after LEEP
Pap smear +/- colpo q 6 mo until 3 negative tests obtained; then annual Paps until 3 negative tests; then q 3 yrs (like everyone else)
Rx for first uncomplicated kidney stone
CT, NSAIDs, fluids >2L/day
(don't need 24 hr urine collection until have recurrent stones)
Soap bubble appearance on xray of distal epiphysis of femur
Giant cell tumor of bone
How to define a saline-responsive metabolic alkalosis, typical causes, and treatment
Urine chloride <20

Hypovolemia or GI proton loss (e.g. vomiting)

IV saline
Polyarthralgia, tenosynovitis, and painless vesiculopustular skin lesions
Disseminated gonococcal infection
Mechanism of warfarin-induced skin necrosis within a few days of starting treatment
Protein C deficiency
Immunocompromised pt w/ cultures growing gram-positive branching rod, partially acid fast
Nocardia asteroides
Rx for nocardiosis
Bactrim
3 ways to distinguish actinomyces and nocardia infections
Actinomyces is anaerobic (nocardia is aerobic) and is more likely to cause cervicofacial disease and sinus tracts and may have sulfur granules
Rx for actinomyces infection
Penicillin G
JAK2 mutation may be seen in
Polycythemia vera
Most common cause of isolated right-sided heart failure
Pulmonary disease (cor pulmonale)
Pathophys of hepatic encephalopathy (4)
Accumulation of ammonia, production of false neurotransmitters, increased CNS sensitivity to inhibitory neurotransmitters, and zinc deficiency
First step in aortic dissection pt w/ HTN
Antihypertensive management (TEE is best diagnostic study, but comes afterward)
Asymmetric oligoarthritis, urethritis, and mouth ulcers
Reactive arthritis (Reiter syndrome)
LAP, O2 sat, and EPO level in polycythemia vera
Elevated
Normal
Low
IVDU w/ pleuritic pain and cavitating lung nodules on CXR
Septic emboli from tricuspid valve endocarditis (most often from S. aureus)
Criteria for MGUS diagnosis
Asymptomatic elevation of monoclonal protein <3

No anemia, lytic bone lesiosn, hypercalcemia, renal insufficiency, or anything else to suggest multiple myeloma
Why is aggressive diuresis not recommended for treatment of ascites?
Risk of hepatorenal syndrome
Most common cause of death in pts with acute MI
Complex ventricular arrhythmia (partial block --> re-entrant arrhythmia, e.g. v fib)
Elderly pt w/ tense bullae and urticarial plaques (+ pruritus)
Bullous pemphigoid
Pathophys of bullous pemphigoid
IgG and C3 deposits at dermal-epidermal junction
Tea and toast diet is associated w/ what dietary deficiency?
Folic acid --> anemia
Mechanism of a transudative pleural effusion
Either increased hydrostatic pressure (e.g. CHF) or decreased oncotic pressure (e.g. liver failure)
Common side effect of dihydropyridine Ca-channel antagonists (e.g. amlodipine)
Peripheral edema
Immigrant w/ high grade periodic fever, anemia, and splenomegaly
Malaria
Risk with HIT
Paradoxically it is thrombogenic, so at risk for arterial and venous clots
3 causes of postchole pain
Sphincter of Oddi syfunction
CBD stone
Functional pain
Risk factors for esophageal cancer: SCC vs. adenocarcinoma
Squamous: smoking/alcohol
Adeno: GERD/ Barrett's
HTN, mild hypernatremia, hypokalemia, metabolic alkalosis
Primary hyperaldosteronism/ Conn's syndrome (excess aldosterone promotes reabsorption of sodium and secretion of K+ and H+ ions)
Renin level in Conn's syndrome
Decreased due to feedback inhibition from high aldosterone
Management of HTN in a pt on OCPs
D/c OCPs
Short-term bloody diarrhea w/o travel history or fever
EHEC O157:H7
Pathophys of GVHD
Recognition of host major and minor HLA antigens by donor T cells --> cell-mediated immune response
Complication of temporal arteritis (other than vision loss)
Aortic aneurysm
Psoriatic arthritis most commonly involves which joints?
DIP joints
Potential complication of aortic dissection that can cause hypotension
Cardiac tamponade
Persistent nasal blockage and episodes of bronchoconstriction in a pt w/ chronic analgesic use for headaches
Aspirin sensitivity syndrome
Pathophys of aspirin sensitivity syndrome
Pseudo-allergic reaction: exaggerated release of vasoactive and inflammatory mediators
Rx for aspirin sensitivity syndrome
Leukotriene inhibitors, topical steroids
FEV1/FVC ratio in obstructive vs. restrictive disease
Obstructive: <80%
Restrictive: >80%
Frequent complication of nephrotic syndrome
Hypercoagulability (multifactorial), most commonly leading to renal vein thrombosis (esp w/ membranous glomerulopathy)
5 other complications of nephrotic syndrome
Protein malnutrition

Microcytic hypochromic anemia (transferrin loss)

Vita D deficiency (loss of cholecalciferol-binding protein)

Decrease thyroxine (loss of TBG)

Increased susceptibility to infection
Chronology of abdominal pain in acute appendicitis
Visceral followed by somatic pain
Rx for acute bleeding in pts with liver failure
FFP (has all the clotting factors)
What is the water bottle sign on CXR indicative of?
Pericardial effusion
Characteristics of a simple renal cyst that requires no follow-up
Thin walls, no solid component, no enhancement
4 worrisome findings of a renal mass
Multilocular
Thickened, irregular walls
Thickened septae w/in the mass
Contrast enhancement
How to diagnose allergic rhinitis
Nasal cytology (for eosinophils; neutrophils would indictae infectious cause)
Other causes of nasal eosinophilia (besides allergic rhintiis)
Nasal polyposis (including aspiring sensitivity) and non-allergic rhinitis
DLCO and pulmonary compliance in interstitial lung disease
Both decreased
Elderly pt w/ asymptomatic femoral bowing on xray
Paget's disease
Pathophys of Paget's
Osteoclast hyperfunction --> mosaic pattern of lamellar bone
Why do pts with obesity hypoventilation syndrome have respiratory acidosis?
Decreaesd chest wall compliance --> increased work of breathing
HIV pt taking all his meds and prophy drugs with hyperkalemia
Likely 2/2 trimethoprim
NPO postop pt who is bleeding is most likely due to
Vitamin K deficiency (so give FFP)
IBD w/ crypt abscess is most likely due to
Ulcerative colitis
Diarrhea w/ intestinal villous atrophy is likely due to
Celiac sprue
Afebrile pt w/ new-onset blood-tinged sputum, cold symptoms, and normal PEX
Likely acute bronchitis (viral); just observe
Pneumonia w/ GI symptoms and hyponatremia
Legionella
Pathophys of Baker cysts
Excessive fluid produced by inflamed synovium (e.g. in RA, OA, and cartilage tears) that accumulates in the popliteal bursa
5 most effective lifestyle ways to lower BP, in order
Weight loss
DASH diet
Dietary sodium restriction
Exercise
Decrease alcohol intake
4 causes of pulsus paradoxus (abnormally large drop in SBP w/ inspiration)
Tamponade
Pericardial effusion
Tension pneumo
Severe asthma
Rx for torsades de pointes
Magnesium sulfate
Pstop pt with syncope/ hypotension, JVD, and RBBB
Massive PE --> cardiogenic shock
Pt w/ hyperactive DTRs after multiple blood transfusions
Hypocalcemia from citrate binding
Acid-base disturbance in primary adrenal failure
Normal AG hyperkalemic, hyponatremic metabolic acidosis (from aldosterone deficiency)
Pathogens associated w/ acute epididymitis
Younger pts w/ urethritis as well: chlamydia or neisseria

Older pts w/ UTI as well: E. coli
Best way to improve survival in COP
Supplemental O2 therapy
Rx for an intubated pt who is persistently hypoxemic despite high FiO2 settings
Add PEEP to prevent alveolar collapse
Cause of hypoxia in pts with PNA
Alveolar and interstitial inflammation --> areas of V/Q mismatch --> increased A-a oxygen gradient
Potential cause of persistent/recurrent chalazion
Meibomian gland carcinoma (sebaceous carcinoma), so needs biopsy
Rx for renal artery stenosis 2/2 fibromuscular dysplasia
Angioplasty w/ stent placement
Which live vaccine can be given to HIV pts?
MMR, if CD4 >200 (b/c measles is life-threatening in HIV pts)
IBD w/ noncaseating granulomas
Crohn's disease
Lymphoblasts in ALL stain
PAS-positive
Palpable purpura, proteinuria, hematuria
Mixed cryoglobulinemia
Many pts w/ mixed cryoglobulinemia also have what infection?
HCV
Systemic vasculitis, upper and lower airway granulomatous inflammation, and glomerulonephritis
Granulomatosis w/ polyangitis (Wegener's)
Rx for Wegener's
Cyclophosphamide
Definitive and intermediate hosts for hydatid cysts (and the pathogen that causes them)
Sheep and dogs, respectively

Echinococcosis
What is anasarca?
Generalized edema (pulm, ascites, swollen extremities)
Size cut-off for worrisome LN
>2cm
Asymmetric polyarthritis before or after purulent monoarthritis
Gonococcal septic arthritis
Painless visual loss w/ optic disk swelling, retinal hemorrhage, dilated veins, and cotton wool spots
CRVO
Painless visual loss w/ optic disc pallor, cherry red fovea, and boxcar segmentation of blood in the retinal veins
CRAO
Temporary visual loss
Amaurosis fugax
Acid-base abnormality in PE
Respiratory alkalosis (due to hyperventilation)
Cholangiography showing beading (dilation) of the intrahepatic and/or extrahepatic bile ducts
PSC
Recent onset confusion, fever, muscle rigidity, and diaphoresis
Neuroleptic malignant syndrome (drug-induced idiosyncratic reaction)
Pathophys of anemia in SLE
Warm autoimmune hemolysis
Pathophys of SLE-associated thrombocytopenia and neutropenia
Antibody mediated destruction
Rx for bartonella
Oral azithromycin
Symmetric duskiness and coolness of all fingertips/ toes in an ICU pt
Norepinephrine-induced vasospasm --> ischemia
Best neuromuscular blocker for a pt with both liver and kidney failure
Atracurium (degrades spontaneously in plasma)
Rx for tick on skin
Remove (ideally within 24hrs) by grabbing mouth w/ tweezers
Cause of presbyopia
Decreased lens elasticity, so can't focus on near objects
Anion gap metabolic acidosis with optic disc hyperemia
Methanol ingestion
Best Rx for cancer-induced cachexia (no appetite)
Progestin agents
Pruritic vesicles and pustules in gray wavy runs over finger webs, heels of palms, and wrist creases + papules over nipples, areola, scrotum, penis
Scabies
Difficulty swallowing, lots of dental caries, enlarged/firm salivary glands
Sjogren Syndrome (lack normal amount of saliva; lymhocytic infiltrate of saliva glands)
Diabetes, hepatomegaly, arthropathy
Hemochromatosis
Pain over the anteromedial tibia just below the joint line, often worst at night (when touching)
Anserine bursitis
Young male with morning pain in his hands
RA
How to differentiate the thickening in hypertrophic vs. restrictive cardiomyopathy
Hypertrophic: septum is thickest
Restrictive: symmetrical thickness
Reversible cause of restrictive cardiomyopathy
Hemochromatosis
Atypical PNA with a skin rash (erythema multiforme: dusky red target shaped lesions)
Mycoplasma
Most common complication of inhaled corticosteroids
Oropharyngeal candidiasis (oral thrush)
Rx for CML and its mechanism
Imatinib (Gleevec): tyrosine kinase inhibitor that binds the ATP binding site of BCR-ABL, preventing conformation change to its active form
Mono symptoms + rash and diarrhea
HIV
Rx for Zenker's diverticulum
Excision, usually with cricopharyngeal myotomy
Rx for sphincter of Oddi dysfunction after chole
ERCP with sphincterotomy
Pathophys of ARDS
Inflammatory mediators from tissue injury damage the alveoli --> alveolar capillary permeability --> fluid leaks into alveoli, causing pulmonary edema
Rx for ARDS
Mechanical ventilation w/ low tidal volumes and PEEP (may require up to 15 cm H2O of PEEP)
Pathophys of statin induced myopathy
Inhibiting HMG CoA also inhibits mevalonate production, which is also used in production of CoQ10 --> myopathy
Tobacco induced white granular texture on mouth
Leukoplakia
Risk of leukoplakia
Transformation into squamous cell carcinoma
Vaccines for HIV pts
Td booster, influenza, S. pneumo, hep A (if pt is MSM), and hep B
Area w/ dullness to percussion and increased fremitus (but normal breath sounds)
Likely consolidation/ PNA
Exam findings with pneumothorax (air in pleural space)
Decreased breath sounds, hyperresonance to percussion, decreased fremitus, transmitted voice sounds
Exam findings w/ fluid in pleural space (effusion)
Blocks sound transmission so dull to percussion, decreased breath sounds, decreased fremitus
Abd pain, diarrhea, malabsorption w/ steatorrhea + migratory polyarthropathy, chronic cough, valvular regurgitation
Whipple's disease
Biopsy in Whipple's disease
PAS-positive material in lamina propria of small intestine
Swollen, pale arm after placement of subclavian line
Subclavian vein thrombosis
Rx for subclavian vein thrombosis
Remove central line first! Then duplex, may need anticoagulation
Management of solid testicular mass
US; if suggestive, radical orchiectomy (don't biopsy! Could spill cancer cells, will diagnose after excision)
Bilateral tearing, intense itching, hyperemia, tearing, and conjunctival/eyelid edema
Allergic conjunctivitis
Cause of aspiration PNA in demented pt
Impaired epiglottic reflex/ swallowing
Rx for hepatic hydrothorax (1st, 2nd, and 3rd line)
Therapeutic thoracentesis + diuretics/ salt restricted diet

TIPS

Liver transplant
Rx for hepatorenal syndrome
Liver transplant
Definition of hepatorenal syndrome
Cirrhosis with renal failure that doesn't respond to volume resuscitation
Hyperglycemia, weight loss, scaly papules on face
Glucagonoma triad
HIV pt w/ bright red, firm, friable, exophytic nodules
Bacillary angiomatosis
Pathogen causing bacillary angiomatosis
Bartonella (gram negative)
Rx for bacillary angiomatosis
Oral erythromycin
HIV pt w/ RUL cavity growing partially acid-fast, filamentous, branching rods
Nocardia
Rx for Nocardia
Bactrim
Criteria for long term O2 therapy in COPD pts (3)
PaO2 <55 or SaO2 <88%

Cor pulmonale, evidence of pulm HTN, or hematocrit <55% change the cut-offs to 59 and 89%

Nocturnal hypoxia
HIV pt w/ LAD, pancytopenia, hepatosplenomegaly, palatal ulcers, and interstitial pneumonitis
Disseminated histoplasmosis
Of histo, blasto, and coccidio, which is unlikely to infect i/c hosts?
Blasto
Red eye w/ leukocytes in anterior chamber
Anterior uveitis
Young pt w/ chest pain and short systolic murmur at apex that disappears w/ squatting
Mitral valve prolapse (squatting increases preload, which decreases murmur)

No explanation for why MVP pts have chest pain
SIADH is most commonly associated w/ what kind of lung cancer?
Small cell carcinoma
What to tell pts who are starting warfarin
Many foods have vitamin K and will decrease its efficacy

Many meds will decrease its efficacy as a side effect
Mechanism of varencicline
Partial agonist of nicotinic acetylcholine receptor
Post eye operation, pt w/ pain, decreased visual acuity, swollen eyelids and conjunctiva, corneal edema and infection
Postop endophthalmitis (infection w/in vitreous of eye)
Rx for postop endophthalmitis
Intravitreal antibiotic injection or vitrectomy
Dx and management of urinary urgency, hesitancy, and nocturia w/ smoothly enlarged prostate w/ elevated creatinine
BPH

Need abd US to r/o hydronephrosis (if so, need Foley and likely a TURP)
Pt with diverticulitis who isn't improving on Abx
CT scan to r/o complications like abscess or fistula
Drugs to avoid in HOCM
Nitrates (or anything that reduces preload: worsens obstruction)
2 cancers tamoxifen places pts at risk of
Uterine endometrial cancer and sarcoma
Other risk of tamoxifen
Venous thrombosis
What do leukocyte esterase and nitrates indicate
LE: pyuria
Nitrates: enterobacteriaceae
Non-tender, indurated neck mass which is draining fluid w/ Gram positive, branching bacteria
Actinomyces
Rx for Actinomyces
High dose IV penicillin for 6-12 wks
Dev't of fever, hemolysis and DIC 30 min after blood transfusion
Acute hemolytic transfusion reaction from ABO or minor antigen mismatched blood
Mono presentation w/ negative heterophile Ab test
Test may be negative early in illness; should repeat
Best test for lactose intolerance
Hydrogen breath test (increase in hydrogen after ingestion of lactose indicates bacterial carb metabolism, i.e. positive test)
Stool tests in lactose intolerance (3)
Low pH, increased osmotic gap, positive test for reducing substances
Which type of ulcers are worse on an empty stomach and why?
Duodenal (unopposed acidic fluid empties into duodenum)
Rx for duodenal ulcer
Abx (90% have H pylori) and PPIs
3 classes of drugs that should be taken w/ folic acid
Anti-epileptics, MTX, TMP
Axillary freckling and cafe au lait spots
Neurofibromatosis, type 1
Ophtho risk w/ neurofibromatosis
Optic glioma
Presentation of optic glioma
Slowly progressive unilateral vision loss, dyschromatopsia, exophthalmos