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28 Cards in this Set
- Front
- Back
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Dx
45 yo with acute flank pain and hematuria |
nephrolithiasis
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MCC of aortic stenosis in 50 y/o
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congenital bicuspid aortic valve
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MOA:
streptokinase |
activates tissue plasminogen --> cleaves fibrin clots
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MOA:
aspirin |
Cox-2 inhibitor --> blocks plt aggregation
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MOA:
clopidogrel |
inhibits ADP receptor
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MOA:
abciximab |
Gp2b3a Inhibitor
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MOA:
tirofiban |
Gp2b3a Inhibitor
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MOA:
ticlopidine |
inhibits ADP receptor
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MOA:
enoxaparin |
LMWH --> inhibits CF Xa
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MOA:
eptifibatide |
Gp2b3a Inhibitor
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classic triad of HUS
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hemolytic anemia
uremia thrombocytopenia |
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what is the pentad of TTP
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hemolytic anemia
uremia thrombocytopenia neurologic sequelea fever |
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lab test to monitor:
warfarin |
PT/INR
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lab test to monitor:
heparin |
PTT
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lab test to monitor:
LMWH |
doesn't need monitoring
(h/w it can be monitored with anti-CF Xa) |
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drugs known to cause thrombocytopenia
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heparin (HIT)
abciximab (GP2b3a inhibitor) carbamazepine, phenytoin, valproate cimetidine acyclovir, rifampin sulfonamides (e.g. sulfasalazine, TMP-SMX) procainamide, quinidine quinine, gold compounds |
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1st line Rx for vWD
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desmopressin, DDAVP (increases vWF secretion)
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Rx for vWD that is severe or refractory
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cryoprecipitate or Factor VIII
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Rx for vWD with menorrhagia
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OCP
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MCC's of DIC
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"STOP Making Thrombi"
S = sepsis T = trauma O = OB complications P = pancreatitis M = malignancy T = transfusions |
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PLT's, BT, PT, PTT:
HUS/TTP |
PLT's: decr'd
BT: incr'd PT: normal PTT: normal |
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PLT's, BT, PT, PTT:
hemophilia A or B |
PLT's: normal
BT: normal PT: normal PTT: incr'd |
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PLT's, BT, PT, PTT:
vWD |
PLT's: normal
BT: incr'd PT: normal PTT: incr'd |
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PLT's, BT, PT, PTT:
DIC |
PLT's: decr'd
BT: incr'd PT: incr'd PTT: incr'd |
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PLT's, BT, PT, PTT:
warfarin use |
PLT's: normal
BT: normal PT: incr'd PTT: incr'd |
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PLT's, BT, PT, PTT:
aspirin |
PLT's: normal
BT: incr'd PT: normal PTT: normal |
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PLT's, BT, PT, PTT:
end stage liver disease |
PLT's: normal/decr'd
BT: normal/incr'd PT: incr'd PTT: incr'd |
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what is the MC mutation that predisposes white pt's to venous thrombosis
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Factor V Leiden mutation
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