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10 Cards in this Set
- Front
- Back
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next step in mgmt:
25 y/o man dx'd with a solitary testicular mas by US |
orchiectomy
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classic findings of HSP
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palpable purpura
GI sx's (e.g. abd'l pain, vomiting, guaiac+, intussusception) renal disease transient arthritis/arthralgias |
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What variables shift the Hb-O2 dissociation curve to the right
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"CADET-face RT"
C: incr'd pCO2 A: incr'd altitiude/acid (i.e. decr' pH) D: incr'd 2,3-DPG E: exercise T: incr'd temp |
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what effect does a right shift on Hb-O2 curve have
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Incr'd delivery of O2 to peripheral tissues
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what is cause of anemia that develops after taking a sulfa drug
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G6PD deficiency
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what lab markers suggest anemia due to hemolysis
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decr'd Hb/Hct with incr'd retics
normal MCV decr'd haptoglobin incr'd indirect bilirubin incr'd LDH |
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in hemolytic anemia, why is serum haptoglobin level der'd & serum LDH increased
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Haptoglobin binds free Hb in blood
LDH spills out of hemolyzed RBC's |
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characteristic findings in hereditary spherocytosis
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jaundice & gallstones (2nd/2 elevated bilirubin)
splenomegaly anemia with incr'd retics & MCHC spherocytes on peripheral smear positive osmotic fragility test |
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spherocytosis is a/w higher incidence of what lab abnormality
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pseudohyperkalemia
(2nd/2 K+ spilling into blood when RBC's lyse after blood draw) |
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tx of hereditary spherocytosis
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folic acid 1mg qD
splenectomy (moderate to severe cases) RBC transfusion (extreme cases) |
