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47 Cards in this Set
- Front
- Back
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Mild Impetigo - treatment
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Topical:
- Mupirocin - Bacitracin - Retapamulin |
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Severe Impetigo - treatment
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Oral:
- Dicloxacillin - Cephalaxin - |
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Impetigo - community acquired MRSA treatment
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- Doxycycline
- Clindamycin - TMP-SMX |
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Impetigo
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epidermis
- strep or staph |
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Erysipelas
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epidermis + dermis
- strep (pyogenes) > staph |
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Erysipelas + penicillin allergic
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- erythromycin
- clarithromycin - clindamycin |
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Severe erysipelas - treatment
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IV antibiotics:
- oxacillin - nafcillin - cefazolin |
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Severe erysipelas + penecillin allergic
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- clindamycin
- vancomycin |
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Erysipelas + MRSA
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- vancomycin
- linezolid - daptomycin - tigecycline - ceftaroline |
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Cellulitis
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dermis --> subcutaneous tissue
- legs > arms ** Staph Aureus |
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Can you get rheumatic fever from a skin infection?
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NO! only glomerulonephritis (strep)
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Cross reaction between penecillins and cephalosporins?
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very small/unlikely
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Diagnostic test for fungal infection
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KOH
(most accurate = fungal culture) |
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Tinea capitis/unguim - treatment
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Oral:
- Terbinafine - Itraconazole |
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Topical antifungals
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* anything besides hair/nails
- Clotrimazole - Ketoconazole - Econazole - Myconazole - Nystatin - Ciclopirax |
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Side effect of oral ketoconazole
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- gynecomastia
- anti-androgenic |
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Morbilliform rash
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- drug hypersensitivity
- no mucous membrane - no treatment "like measles" |
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Erythema Multiforme
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- "target lesions"
- on trunk - no mucous membrane - drugs, herpes, mycoplasma |
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Steven Johnson
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- mucous membranes --> respiratory failure :(
- steroids don't help --> IV IG |
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Toxic Epidermal Necrolysis
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- like SJ but greater % body
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TSS vs. SSSS
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- both staph
- SSSS = just skin - TSS = skin + organ failure |
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TSS
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- hypotension
- renal disfunction - liver disfunction - CNS involvement |
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TSS/SSSS treatment
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Anti-staph: "ox/clox/diclox/naf"
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TSS causes
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- nasal packing
- sutures |
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Acne treatment mild --> severe
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1. topical benzoyl peroxide
2. clinda/erythro (topical) 3. topical Vit. A (tretinoin, adapalene, tazarotene) 4. oral antibiotics - minocyclin, doxycycline 5. oral vit A (isotretinoin) |
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Widespread melanoma - treatment
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- interferon injection
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melanoma metastasis
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brain
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squamous cell carcinoma - risk factors
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- organ transplant b/c immunosuppressive drugs
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what type of AIDS is kaposis sarcoma associated with?
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- sexually transmitted NOT injection drugs
- in GI tract, lungs |
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Kaposi sarcoma - treatment
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1. ** antiretrovirals **
2. intralesional injections interferon or vincristine 3. liposomal doxorubicin |
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Actinic Keratosis Removal
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- topical 5 FU
- curettage - cryotherapy - laser - imiquimod (local immunostimulant -- T cells) |
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Atopic Dermatitis (eczema)
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- overactive mast cells
- unprovoked release of histamine |
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Atopic dermatitis - treatment
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1. topical corticosteroids
2. tacrolimus and pimecrolimus - T cell inhibitors, topical 3. Antihistamines: - mild = cetirizine, fexofenadine, loratidine - severe =hydroxyzine, diphenhydramine, doxepine 4. antibiotics (impetigo) 5. UV light |
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Psoriasis treatment - Localized
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1. topical steroids: fluocinonide, amcinolone, bethamethasone, clobesalol
2. Vit A& D ointment 3. coal tar 4. tacrolimus, pimecrolimus |
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Psoriasis treatment - Extensive
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1. UV light
2. TNF inhibitors: etanercept, adulimumab, infliximab 3. MTX |
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Topical steroid side effects
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Atrophy!
- inhibit collagen formation/growth - AAs --> glucose - gluconeogenesis |
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MTX side effects
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lung and liver fibrosis
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Pityriasis Rosea
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- single lesion --> spreads
- transient - UV light, steroids - looks like syphillis |
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Seborrheic Dermatitis (dandruff) - treatment
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- topical steroids/antifungals
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Seborrheic Dermatitis - risk factors
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- AIDS
- Parkinsons |
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Drug induced pemphigus vulgaris
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- ACEI
- penecillamine - phenobarbital - penecillin |
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Pemphigus vulgaris - treatment
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1. Systemic steroids
2. Azathioprine, Mycophenalate 3. Rituximab (anti-CD 20), IVIG |
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Bullous pemphigoid - treatment
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1. Prednisone
2. Azathiprone, cyclophosphamide, mycophenalate 3. erythromycin, dapsone, nicotinamide - mild disease |
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Poryphrea cutanea tardia
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- blistering in sun-exposed areas
- abnormal porphyrin reaction ** Associated with: liver disease (hep C, alcohol...), Estrogen use, hemochromatosis |
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porphyria cutanea tardia - test
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24 hr. urine uroporphyrins
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Poryphrea cutanea tardia - deficiency
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uroporphyrin decarboxylase
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Poryphrea cutanea tardia - treatment
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treat underlying cause
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