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3 Cards in this Set
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antimetabs
MTX MOA? |
MOA:
Folic acid analog that inhibits DHFR so no DNA or Protein syn |
|
antimetabs
MTX for? |
For:
Cancer liquids--Leuk/Lympho, solids--chorio/sarco Imm supr--RA, PA, MS, Abortion, ectopics |
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antimetabs
MTX AE? |
1. myelo supr,"", Leurovorin Rescue (folinic acid)!
2. fatty liver 3. mucositis 4. teratogen --> NTD |