Step 1 Pharm Renal 1

Front 1

carbonic anhydrase inhibitor

Back 1

aceta--zo--lamide

Front 2

aceta--zo--lamide

Back 2

CA inhibitor

Front 3

inhibits CA. used to treat glaucoma

Back 3

aceta--zo--lamide

Front 4

aceta--zolamide use

Back 4

glaucoma. urinary alkalinziation. metabolic alkalosis. altitude sickness.

Front 5

causes HCO3 wasting at PT

Back 5

aceta--zolamide

Front 6

HCO3 wasting at PT so
increase HCO3 in tubules results in

Back 6

alkalinizes urine.
metabolic acidosis b/c decreased HCO3 in blood.

Front 7

alkalinizes urine.

Back 7

aceta--zolamide

Front 8

tx for metabolic alkalosis and altitude sickness

Back 8

aceta--zolamide

Front 9

toxicity includes hyperchloremic metabolic acidosis
sulfa allergy
NH3 toxicity
neuropathy

Back 9

aceta--zolamide

Front 10

aceta--zolamide toxicity causes what type of allergy

Back 10

sulfa

Front 11

mannitol mecha of action

Back 11

osmotic diuretic
increases tubular flow so
increases urine flow

Front 12

aceta--zolamide
furosemide
hydrochlorothiazide

Back 12

all can cause sulfa allergy

Front 13

NH3 toxicity and neuropathy

Back 13

aceta--zolamide

Front 14

renal drugs that cause acidemia

Back 14

aceta--zolamide
K+ sparing

Front 15

acetazolamide
K sparing diuretics

Back 15

cause acidemia

Front 16

renal drugs that causes alkalemia

Back 16

loop diuretics- furosemide, ethacrynic acid
thiazides

Front 17

loop diuretics- furosemide, ethacrynic acid
thiazides

Back 17

cause alkalemia

Front 18

diuretic that abolishes medulla hypertonicity so can't concentrate urine

Back 18

furosemide

Front 19

diuretic that abolishes ascending LH lumenal (+) potential inhibits

Back 19

furosemide.
inhibits paracellular Ca reabsorption so
increase Urine Ca

Front 20

increases Urine Ca

Back 20

furosemide

Front 21

tx for hypercalcemia

Back 21

furosemide

Front 22

OH DANG

Back 22

furosemide toxicity

Front 23

toxicity can cause
ototoxicity, hypokalemia
dehydration, allergy (sulfa)
nephritis (interstitial), gout

Back 23

furosemide

Front 24

ototoxicity

Back 24

furosemide

Front 25

toxicity can cause gout

Back 25

furosemide

Front 26

acts like furosemide

Back 26

ethacrynic acid

Front 27

diuretic that can be used in those allergic to sulfa drugs

Back 27

ethacrynic acid

Front 28

ethacrynic acid CANNOT be used to treat

Back 28

gout

Front 29

contraindicated in gout

Back 29

ethacrynic acid

Front 30

tx hyperuricemia

Back 30

ethacrynic acid

Front 31

decreases Urine Ca

Back 31

hydrochlorothiazide

Front 32

hydrochlorothiazide decreases excretion of

Back 32

Ca. so decreases Urine Ca

Front 33

tx for hypercalcciuria- too much Ca in urine

Back 33

hydrochlorothiazide

Front 34

tx for nephrogenic diabetes insipiduse

Back 34

hydrochlorothiazide

Front 35

hydrochlorothiazide can be used to tx

Back 35

nephrogenic diabetes insipidus

Front 36

toxicity includes hyper:
glycemia
lipidemia
uricemia
calcemia
Also, sulfa allergy

Back 36

hydrochlorothiazide

Front 37

causes hyperlipidemia

Back 37

hydrochlorothiazide

Front 38

causes hyperglycemia

Back 38

hydrochlorothiazide

Front 39

one drug can tx hyperuricemia, other causes hyperuricemia

Back 39

tx- ethacrynide
cause- hydrochlorothiazide

Front 40

toxicity includes hypercalcemia

Back 40

hydrochlorothiazide

Front 41

competitive aldosterone R antagonist in cortical CT

Back 41

spironolactone

Front 42

spironolactone mecha of action

Back 42

competitive aldosterone R antagonist in cortical CT

Front 43

block Na channels in Cortical CT

Back 43

triamterene
amiloride
eplerenone

Front 44

amiloride mecha of action

Back 44

blocks Na channel in cortical CT

Front 45

triamterene

Back 45

blocks Na channel in cortical CT

Front 46

toxicity includes gynecomastia,
antiandrogen effects

Back 46

spironolactone

Front 47

T or F. all diuretics increase Urine NaCl

Back 47

true

Front 48

all diuretics except ? increase Urine K

Back 48

spironolactone
triampterene
amiloride
eplerenone

Front 49

eplerenone

Back 49

K sparing diuretic

Front 50

captopril
enalapril
lisinopril

Back 50

ACE inhibitors

Front 51

angiotensin II receptor antagonist

Back 51

losartan

Front 52

losartan

Back 52

AT II receptor antagonist

Front 53

does not cause cough

Back 53

losartan

Front 54

inhibiting ACE causes

Back 54

decreases AT II
decreases bradykinin inhibition
increases Renin release b/c no neg feedback from ACE

Front 55

contraindicated in bilateral renal artery stenosis

Back 55

ACE inhibitors

Front 56

cap--to--pril cannot be used in

Back 56

bilateral artery stenosis

Front 57

ena--la--pril

Back 57

ACE inhibitor

Front 58

lisinopril

Back 58

ACE inhibitor

Front 59

diuretics that can cause hyperkalemia

Back 59

spironolactone, tri-am-terene, amiloride
captopril, enalapril, lisinopril

Front 60

K sparing
ACE inhibitors

Back 60

can cause hyperkalemia

Front 61

diuretics with toxicity that includes rash and taste changes

Back 61

enalapril
captopril
lisinopril

Front 62

diuretics that prevent proteinuria

Back 62

ACE inhibitors

Front 63

diuretics that have cough, angioedema, hypotension as toxicities

Back 63

ACE inhibitors

Front 64

diuretics that can cause pregnancy problems

Back 64

ACE inhibitors

Front 65

captopril, enalapril, lisinopril and pregnancy

Back 65

drugs can cause pregnancy problems

Front 66

diuretics that can cause hyperkalemia, increased renin, lower AT II

Back 66

ACE inhibitors

Front 67

ACE inhibitors and skin

Back 67

can cause rash

Front 68

ACE inhibitors and taste

Back 68

can cause taste change

Front 69

bradykinin is

Back 69

potent vasodilator
causes cough- consequence of ACE inhibitor therapy

Front 70

contraindicated in anuria and CHF

Back 70

mannitol

Front 71

toxicity includes edema and dehydration.

Back 71

mannitol

Front 72

tx for shock, drug OD and increasesd ICP & intraocular P

Back 72

mannitol

Front 73

mannitol cannot be used with

Back 73

CHF, anuria