Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
29 Cards in this Set
- Front
- Back
|
Cancers that cause hypercalcemia (3)
|
Squamous cell lung carcinoma (PTHrp)
Renal cell carcinoma (PTHrp) Breast carcinoma (PTHrp) |
|
|
Cancers that cause Cushing's syndrome (2)
|
Small cell lung cancer, medullary carcinoma of the thyroid
|
|
|
Cancers that cause SIADH (2)
|
Small cell lung cancer, intracranial neoplasms (eg, pituitary adenoma)
|
|
|
Cancers that cause polycythemia (2)
|
Renal cell carcinoma, hemangioblastoma
|
|
|
Cancers that cause Lambert-Eaton syndrome (muscle weakness) [2]
|
Thymoma, small cell lung cancer
|
|
|
Cancers that cause gout and urate nephropathy (1)
|
Hematologic malignancy (leukemia, lymphoma)
Due to tumor lysis (release of nitrogenous wastes from cells) |
|
|
Mechanism of paraneoplastic Cushing's syndrome
|
ACTH or ACTH-like peptide from small cell lung cancer
|
|
|
Mechanism of SIADH in paraneoplastic syndromes
|
Secretion of ADH by small cell lung cancer, or pituitary adenoma
|
|
|
Mechanism of hypercalcemia in cancer
|
PTH-related peptide (PTHrp), TGF-beta, TNF, IL-1 production in squamous cell lung cancer, renal cell carcinoma, breast carcinoma
|
|
|
Mechanism of polycythemia caused by cancer as a paraneoplastic effect
|
EPO production, as in renal cell carcinoma and hemangioblastoma
|
|
|
Mechanism of Lamber-Eaton syndrome (muscle weakness) in paraneoplastic syndromes
|
Antibodies against PRE-synaptic Ca channels at the NMJ, produced in thymoma and small cell lung cancer
|
|
|
Mechanism of gout and urate nephropathy in paraneoplastic syndromes
|
Excess nucleic acid turnover results in hyperuricemia (eg, cytotoxic therapy)
|
|
|
Small cell lung cancer
|
ACTH, ADH, antibodies against Ca channels at the NMJ
|
|
|
Intracranial neoplasms
|
ADH
|
|
|
Squamous cell lung cancer
|
PTHrp
(and TGF-beta, TNF, IL-1) |
|
|
Renal cell carcinoma
|
PTHrp, EPO
(also TGF-beta, TNF, IL-1) |
|
|
Breast carcinoma
|
PTHrp, TGF-beta, TNF, IL-1
|
|
|
Hemangioblastoma
|
EPO
|
|
|
Thymoma
|
Antibodies against Ca channels at the NMJ
|
|
|
Carcinoid tumor of the lung
|
5-HT (producing carcinoid syndrome)
|
|
|
Colorectal cancer metastases to liver
|
5-HT (producing carcinoid syndrome)
|
|
|
This tumor can be associated with hypoglycemia
|
Hepatocellular carcinoma
(secretes insulin-like growth factor) |
|
|
This tumor can be associated with hyponatremia
|
Small cell carcinoma of lung
|
|
|
This tumor can be associated with gynecomastia
|
Choriocarcinoma of the testes
|
|
|
These two tumors can be associated with a Cushing syndrome
|
Small cell carcinoma of lung
Medullary carcinoma of the thyroid |
|
|
Black, verrucoid-appearing lesions can be seen in this cancer
|
Stomach carcinoma (acanthosis nigricans)
|
|
|
Muscle weakness can be seen in these cancers
|
Small cell lung cancer (Eaton-Lambert syndrome)
Thymoma (myasthenia gravis) |
|
|
Sudden appearance of numerous pigmented seborrheic keratoses can be seen in this cancer
|
Stomach carcinoma
|
|
|
Superficial migratory thrombophlebitis can be seen in this cancer
|
Pancreatic carcinoma (Trousseau's sign; due to release of procoagulants)
|
