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20 Cards in this Set
- Front
- Back
abl
|
CML
|
|
c-myc
|
Burkitt's lymphoma
|
|
bcl-2
|
Follicular, undifferentiated lymphoma (inhibits apoptosis)
|
|
erb-B2
|
Breast, ovarian, gastric
(GH receptor) |
|
ras
|
Colon carcinoma
|
|
L-myc
|
Lung tumor
(nuclear transcription factor) |
|
N-myc
|
Neuroblastoma
|
|
ret
|
MEN IIa, MEN IIb
|
|
c-kit
|
Gastrointestinal stromal tumor (GIST)
|
|
Rb
|
Retinoblastoma, osteosarcoma
|
|
BRCA1
|
Breast cancer, ovarian cancer
|
|
BRCA2
|
Breast cancer
|
|
p53
|
Most cancer; Li-Fraumeni syndrome
|
|
p16
|
Melanoma
|
|
APC
|
Colorectal cancer (assoc. with FAP)
|
|
WT1
|
Wilm's tumor (nephroblastoma)
[Recall that WT1 is involved in the development of the urogenital system] |
|
NF1
|
Neurofibromatosis type 1
|
|
NF2
|
Neurofibromatosis type 2
|
|
DPC
|
Pancreatic cancer ("deleted in pancreatic cancer")
|
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DCC
|
Colon cancer ("deleted in colon cancer")
|