Step 1 First Aid: Pharmacology

Front 1

K_m reflects ___

Back 1

substrate affinity for enzyme (inversely)

Front 2

V_max is a function of ___

Back 2

enzyme concentration

Front 3

low ___ means high enzyme affinity

Back 3

K_m

Front 4

inhibitors are studied with graph of ___ vs. ___
this is aka ___ plot (2)

Back 4

1/V
1/[S]
double reciprocal
Lineweaver-Burk

Front 5

x intercept of double reciprocal plot is ___

Back 5

-1/K_m

Front 6

y intercept of double reciprocal plot is ___

Back 6

1/V_max

Front 7

K_m is the ___ at which V is ___

Back 7

substrate concentration
V_max/2

Front 8

competitive/noncompetitive inhibitors do not change V_max

Back 8

competitive

Front 9

competitive/noncompetitive inhibitors do not change K_m

Back 9

noncompetitive

Front 10

efficacy change means ___ of dose response curve

Back 10

vertical shift

Front 11

potency change means ___ of dose response curve

Back 11

horizontal shift

Front 12

competitive inhibitors change ___

Back 12

potency

Front 13

non-competitive inhibitors change ___

Back 13

efficacy

Front 14

V_d in terms of plasma drug concentration

Back 14

V_d = (amount of drug in body)/(plasma concentration)

Front 15

drugs with low V_d distribute in ___
drugs with medium V_d distribute in ___
drugs with high V_d distribute in ___

Back 15

blood
ECF or TBW
tissues

Front 16

low V_d means ___ L

Back 16

4--8

Front 17

clearance (CL) in terms of plasma drug concentration (C_p)

Back 17

CL = (rate of drug elimination)/(C_p)

Front 18

CL in terms of V_d

Back 18

CL = V_d x K_e

Front 19

t_1/2 in terms of V_d

Back 19

t_1/2 = (0.7 x V_d)/CL

Front 20

loading dose in terms of V_d

Back 20

LD = (C_p x V_d)/F

where F is bioavailability

Front 21

maintenance dose in terms of C_p

Back 21

MD = (C_p x CL)/F

Front 22

zero order kinetics means

Back 22

constant elimination per unit time

Front 23

3 drugs with zero order kinetics

Back 23

phenytoin
ethanol
aspirin

Front 24

first order kinetics means

Back 24

constant fraction of drug eliminated per unit time

Front 25

4 weak acid drugs
treat overdose of weak acid with ___

Back 25

phenobarbital
MTX
TCAs
aspirin
bicarbonate

Front 26

weak base drug
treat weak base overdose wtih ___

Back 26

amphetamine
ammonium chloride

Front 27

phase I metabolism is done by ___
its products are active/inactive
3 phase I reactions

Back 27

CYP450
active
reduction
oxidation
hydrolysis

Front 28

phase II metabolism products are active/inactive,
polar/nonpolar
3 phase II reactions

Back 28

inactive
very polar
glucuronidation
acetylation
sulfation

Front 29

geriatric patients lose phase ___ metabolism first

Back 29

I

Front 30

a partial agonist has higher/lower potency and
higher/lower efficacy
than full agonist.

Back 30

higher OR lower OR same
lower

Front 31

therapeutic index

Back 31

TI = LD_50/ED_50

where LD_50 is median toxic dose,
ED_50 is median effective dose

Front 32

the first synapse in a parasympathetic pathway is ___

Back 32

nicotinic

Front 33

the second synapse in a parasympathetic pathway is ___

Back 33

muscarinic

Front 34

the first synapse in a sympathetic pathway is ___

Back 34

nicotinic

Front 35

the second synapse in most sympathetic pathways is ___
2 exceptions are ___

Back 35

noradrenergic
sweat gland
renal vascular smooth muscle

Front 36

2nd synapse in sweat gland pathway is ___

Back 36

muscarinic

Front 37

2nd synapse in renal vascular smooth muscle pathway is ___

Back 37

D1 dopaminergic

Front 38

nicotinic receptor is ___tropic
muscarinic receptor is ___tropic

Back 38

iono
metabo

Front 39

nicotinic receptor is a ___-gated ___ channel

Back 39

ligand
Na+/K+

Front 40

alpha1 adrenergic effect on eye

Back 40

dilator muscle contraction

Front 41

alpha_1 adrenergic receptor type

Back 41

G_qPLR

Front 42

alpha_1 adrenergic affect on GIT

Back 42

increased sphincter contraction

Front 43

alpha_2 adrenergic receptor type
alpha 2 effect on metabolism

Back 43

G_iPLR
decreased insulin release

Front 44

beta_1 adrenergic receptor type

Back 44

G_sPLR

Front 45

beta_1 adrenergic affect on kidney

Back 45

increased renin release

Front 46

beta_1 adrenergic affect on metabolism

Back 46

increased lipolysis

Front 47

beta_2 adrenergic affect on vessels

Back 47

vasodilation

Front 48

both beta_1 and beta_2 affect the heart but ___ is stronger
only ___ affects the lungs, causing ___

Back 48

beta_1
beta_2
bronchodilation

Front 49

beta_2 adrenergic affect on metabolism (3)

Back 49

increased lipolysis
increased glycogenolysis
increased insulin release

Front 50

beta_2 adrenergic affect on eye

Back 50

increased aqueous humor production

Front 51

M1 muscarinic receptor is ___
M2 muscarinic receptor is ___
M3 muscarinic receptor is ___

Back 51

G_qPLR
G_iPLR
G_qPLR

Front 52

M2Rs are expressed by ___ and do ___

Back 52

cardiomyocytes
negative inotropism and chronotropism

Front 53

M3Rs do ___ to exocrine glands

Back 53

increase secretion

Front 54

M3Rs do ___ to GIT smooth muscle

Back 54

increase peristalsis

Front 55

M3Rs do ___ to lungs

Back 55

bronchoconstriction

Front 56

M3Rs do ___ (2) to eye

Back 56

pupillary sphincter contraction (miosis)
ciliary muscle contraction (accomodation)

Front 57

M3Rs do ___ to bladder

Back 57

detrusor contraction

Front 58

D1Rs are ___
they do ___

Back 58

G_sPLR
renal vascular smooth muscle relaxation

Front 59

D2Rs are ___
they do ___

Back 59

G_iPLR
neurotransmitter modulation

Front 60

histamine H1Rs are ___

Back 60

G_qPLR

Front 61

H1Rs do ___ (4)

Back 61

RT mucus secretion
bronchoconstriction
itching
pain

Front 62

histamine H2Rs are ___
they do ___

Back 62

G_sPLR
gastric acid secretion

Front 63

ADH V1Rs are ___
they do ___

Back 63

G_qPLR
vasoconstriction

Front 64

ADH V2Rs are ___
they do ___

Back 64

G_sPLR
H2O reabsorption in collecting duct

Front 65

Y is converted to ___ by ___.
this is blocked by ___, which works as a ___

Back 65

DOPA
Y hydroxylase
metyrosine
antihypertensive

Front 66

DOPA is converted to ___ by ___.
cofactor is ___

Back 66

DA
DOPA decarboxylase (AAADC)
B6

Front 67

DA is imported to vesicles by ___.
this is blocked by ___

Back 67

VMAT (vesicular monoamine transporter)
reserpine

Front 68

DA is converted to ___ by ___.
cofactor is ___

Back 68

NE
DBH (DA beta hydroxylase)
vitamin C

Front 69

In ___, NE is converted to ___ by ___, in the ___.
___ is required

Back 69

adrenal medulla
E
PNMT (phenylethanolamine N-methyl transferase)
cytoplasm
SAM

Front 70

After MAO-COMT in either order, DA becomes ___

Back 70

HVA (homovanillic acid)

Front 71

After MAO-COMT in either order, E becomes ___ and NE becomes ___

Back 71

both become MHPG (methoxyhydroxyphenylglycol)

Front 72

After COMT, E becomes ___ and NE becomes ___.

Back 72

metanephrine
normetanephrine

Front 73

adrenal pheochromocytomas make more ___ than ___, but other ones do the opposite

Back 73

E
NE

Front 74

catecholamine exocytosis is potentiated by ___ (2) and inhibited by ___

Back 74

amphetamine
ephedrine
guanethidine

Front 75

___ (3) blocks catecholamine reuptake

Back 75

cocaine
amphetamine
TCAs

Front 76

2 presynaptic receptors which inhibit catecholamine release

Back 76

alpha_2
M2

Front 77

1 presynaptic receptor which facilitates catecholamine release

Back 77

AII (angiotensin)

Front 78

rate limiting step of cholinergic neurotransmission is ___
this is inhibited by ___

Back 78

Ch uptake
hemicholinium

Front 79

ACh is synthesized by ___ from ___ and ___

Back 79

choline acetyltransferase (ChAT)
choline
Ac CoA

Front 80

uptake of ACh into vesicule is inhibited by ___
vesicular exocytosis is inhibited by ___

Back 80

vesamicol
botulinum

Front 81

direct cholinomimetic for GI motility

Back 81

bethanechol

Front 82

2 indications for bethanechol

Back 82

ileus (post op, neurogenic)
urinary retention
b/c it activates bladder and bowel

Front 83

2 direct cholinomimetics for glaucoma

Back 83

pilocarpine
carbachol

Front 84

pilocarpine causes contraction of ___ (2)
and secretion of ___ (3)

Back 84

pupillary sphincter
ciliary body
saliva
sweat
tears

Front 85

contraction of ___ helps open angle glaucoma
contraction of ___ helps closed angle glaucoma

Back 85

ciliary body
sphincter pupillae

Front 86

direct cholinomimetic for testing asthma

Back 86

methacholine

Front 87

indirect cholinomimetics are ___s

Back 87

AChEI

Front 88

indirect cholinomimetic for GI motility

Back 88

neostigmine

Front 89

neostigmine has high/low CNS penetration

Back 89

low

Front 90

4 neostigmine indications

Back 90

ileus (post op, neurogenic)
urinary retention
MG
post op NMJ block reversal

Front 91

cholinomimetic for MG dx

Back 91

edrophonium

Front 92

cholinomimetic for MG tx

Back 92

pyridostigmine

Front 93

2 indirect cholinomimetics for glaucoma

Back 93

echothiophate
physiostigmine

Front 94

pyridostigmine has high/low CNS penetration
physiostigmine has high/low CNS penetration
echothiophate has high/low CNS penetration

Back 94

low
high
low

Front 95

cholinergic intoxication causes CNS ___
and skeletal muscle ___

Back 95

excitation
excitation

Front 96

2 antidotes for cholinergic intoxication

Back 96

atropine
pralidoxime

Front 97

pralidoxime functions in cholinergic intoxication by ___

Back 97

regenerating active ChE

Front 98

antimuscarinic for eye

Back 98

atropine
homatropine
tropicamide

Front 99

atropine causes ___ (2)

Back 99

mydriasis
cycloplegia

Front 100

cycloplegia means ___

Back 100

inability to accomodate

Front 101

antimuscarinic for Parkinson's disease

Back 101

benztropine

Front 102

antimuscarinic for motion sickness

Back 102

scopolamine

Front 103

2 antimuscarinic for asthma and COPD

Back 103

ipratropium
tiotropium

Front 104

2 antimuscarinics for bladder spasticity

Back 104

oxybutynin
darifenacin
solifenacin

Front 105

glycopyrrolate used for ___ (3)

Back 105

reduce airway secretions
drooling
peptic ulcers

Front 106

atropine effects

Back 106

eye: pupil dilation, cycloplegia
respiratory: decreased secretions from airway
stomach: decreased acid secretion
gut: decreased motility
bladder: decreased urgency in cystitis

Front 107

atropine toxicity

Back 107

hot
dry
red
blind (cycloplegia)
mad (disoriented)

may cause acute angle-closure glaucoma, urinary retention (in BPH men or hyperthermic infants)

Front 108

at low doses E agonizes ___
at higher doses it agonizes ___

Back 108

beta_1
all adrenergic receptors

Front 109

E is indicated for ___ (4)

Back 109

anaphylaxis
open angle glaucoma
asthma
hypoTN

Front 110

NE agonizes ___

Back 110

alpha_1 > alpha_2 > beta_1

Front 111

NE is indicated for ___

Back 111

hypoTN (*decreases renal perfusion)

Front 112

isoproterenol agonizes ___

Back 112

beta_1 = beta_2

Front 113

isoproterenol is indicated for ___

Back 113

evaluation of tachyarrhythmias

Front 114

DA agonizes ___

Back 114

D1 = D2 > beta adrenergic > alpha adrenergic

Front 115

DA is indicated for ___ (3)

Back 115

shock
heart failure
unstable bradycardia

Front 116

DA's effects on the heart

Back 116

+ inotrope
+ chronotrope
at high doses

Front 117

dobutamine agonizes ___

Back 117

beta_1 > beta_2 > alpha

Front 118

dobutamine is indicated for ___ (3)

Back 118

heart failure
cardiac stress testing

Front 119

dobutamine's effects on the heart

Back 119

inotropic > chronotropic

Front 120

phenylephrine agonizes ___

Back 120

alpha_1 > alpha_2

Front 121

phenylephrine is indicated for ___ (3)

Back 121

pupil dilation
nasal decongestion
hypotension

Front 122

5 beta_2-selective agonists

Back 122

metaproterenol
albuterol
salmetrol
terbutaline
ritodrine

Front 123

2 beta_2 agonists for acute asthma

Back 123

metaproterenol
albuterol

Front 124

beta_2 agonist for chronic asthma tx

Back 124

salmetrol

Front 125

2 tocolytic beta_2 agonist

Back 125

terbutaline
ritodrine

Front 126

3 indirect sympathomimetics
of these ___ (2) are secretagogues

Back 126

amphetamine
ephedrine
cocaine

amphetamine
ephedrine

Front 127

3 amphetamine indications

Back 127

narcolepsy
obesity
ADD

Front 128

3 ephedrine indications

Back 128

nasal decongestion
urinary incontinence
hypoTN

Front 129

what drug should you avoid prescribing in patients with cocaine intoxication?

Back 129

beta blockers because of the unopposed alpha 1 activation leading to extreme hypertension

Front 130

2 alpha_2 agonists

Back 130

clonidine
alpha-methyldope

Front 131

alpha_2 agonists are indicated for ___ with ___

Back 131

HTN
renal disease

Front 132

2 non-selective alpha blockers
___ is reversible blocker

Back 132

phenoxybenzamine
phentolamine
phentolamine

Front 133

non-selective alpha blockers are used for ___ in context of ___
phentolamine is used for ___
phenoxybenzamine is used for ___

Back 133

HTN
pheochromocytoma
hypertensive crisis
chronic (& preop) management

Front 134

alpha_1 selective blockers end in ___

Back 134

zosin

Front 135

alpha_1 blockers are indicated for

Back 135

HTN
urinary retention from BPH

Front 136

3 alpha_1 SEs

Back 136

1st dose orthostatic hypoHTN
dizziness
H/A

Front 137

alpha_2 selective blocker

Back 137

mirtazapine

Front 138

mirtazapine is indicated for ___

Back 138

depression

Front 139

3 mirtazapine SEs

Back 139

sedation
hyperlipidemia
hyperphagia

Front 140

SBP effects of low dose E are via ___ R
low dose E ___s SBPDBP effects of low dose E are via ___ R
low dose E ___s DBP
low dose E does ___ to MAP

Back 140

beta_1
raises
beta_2
lowers
no change

Front 141

SBP effects of NE are via ___ R
E ___s SBPDBP effects of E are via ___ R
E ___s DBP
E does ___ to MAP

Back 141

beta_1
raises
alpha_1
raises
raises

Front 142

SBP effects of isoproterenol are via ___ R
E ___s SBPDBP effects of E are via ___ R
E ___s DBP
E does ___ to MAP

Back 142

beta_1
transient raise, then lower
beta_2
lowers
lowers

Front 143

administering a mixed adrenergic agonist such as ___ after alpha blocker causes ___, whereas administering an alpha agonist such as ___ after alpha block causes ___

Back 143

E
depressor effect
phenylephrine
no effect

Front 144

beta blockers do ___ to BP
mechanism is ___

Back 144

reduce
reduced renin release (JGA beta adrenoceptors)

Front 145

2 beta blockers for SVT

Back 145

propranolol
esmolol

Front 146

sexual SE of beta blocker

Back 146

impotence

Front 147

acebutolol is ___-selective beta blocker

Back 147

beta_1

Front 148

atenolol is ___-selective beta blocker

Back 148

beta_1

Front 149

betaxolol is ___-selective beta blocker

Back 149

beta_1

Front 150

esmolol is ___-selective beta blocker

Back 150

beta_1

Front 151

labetalol is ___-selective beta blocker

Back 151

non

Front 152

metoprolol is ___-selective beta blocker

Back 152

beta_1

Front 153

nadolol is ___-selective beta blocker

Back 153

non

Front 154

pindolol is ___-selective beta blocker

Back 154

non

Front 155

propranolol is ___-selective beta blocker

Back 155

non

Front 156

timolol is ___-selective beta blocker

Back 156

non

Front 157

2 non-selectve alpha + beta blockers

Back 157

carvedilol
labetalol

Front 158

2 partial beta agonists

Back 158

pindolol
acebutolol

Front 159

tx for acetaminophen poisoning

Back 159

N-acetyl cysteine

Front 160

tx for salicylate poisoning (2)

Back 160

bicarbonate
dialysis

Front 161

purpose of bicarbonate in salicylate poisoning

Back 161

alkalinize urine

Front 162

tx for amphetamine poisoning

Back 162

ammonium chloride

Front 163

purpose of ammonium chloride in amphetamine poisoning

Back 163

acidify urine

Front 164

tx for anticholinesterase poisoning (2)

Back 164

atropine
pralidoxime

Front 165

tx for antimuscarinic toxicity

Back 165

physiostigmine salicylate

Front 166

tx for beta blocker toxicity

Back 166

glucagon

Front 167

tx for digitalis toxicity (5)

Back 167

stop digitalis
normalize K+
lidocaine
anti-dig Fab
Mg2+

Front 168

tx for Fe toxicity

Back 168

desferoxamine

Front 169

tx for Pb toxicity (4)

Back 169

CaEDTA
dimercaprol
succimer
penicillamine

Front 170

tx for As/Au/Pb toxicity (4)

Back 170

dimercaprol
succimer
penicillamine
CaEDTA

Front 171

tx for Cu toxicity

Back 171

penicillamine

Front 172

tx for CN- toxicity (3)

Back 172

nitrite
hydroxocobalamin
thiosulfate

Front 173

tx for methemoglobinemia (2)

Back 173

methylene blue
vitamin C

Front 174

tx for CO toxicity (2)

Back 174

100% O2
hyperbaric O2

Front 175

tx for MeOH/ethylene glycol toxicity (3)

Back 175

ethanol
dialysis
fomepizole

Front 176

tx for opioid toxicity

Back 176

naloxone

Front 177

tx for benzo toxicity

Back 177

flumazenil

Front 178

tx for TCA toxcity

Back 178

bicarbonate

Front 179

purpose of bicarbonate in TCA toxicity

Back 179

alkalinize serum

Front 180

tx for heparin toxicity

Back 180

protamine

Front 181

tx for warfarin toxicity (2)

Back 181

vitamin K
FFP

Front 182

tx for tPA/streptokinase toxicity

Back 182

aminocaproic acid

Front 183

tx for theophylline toxicity

Back 183

beta blocker

Front 184

Fe poisoning is particularly common with ___

Back 184

kids

Front 185

Fe is cytotoxic because of ___

Back 185

membrane lipid peroxidation

Front 186

acute Fe poisoning presents with ___

Back 186

gastric bleeding

Front 187

chronic Fe poisoning presents wtih ___ (2)

Back 187

metabolic acidosis
GI obstruction 2' to scarring

Front 188

drugs causing atropine-like SEs

Back 188

TCA

Front 189

2 drugs causing coronary vasospasm

Back 189

cocaine
sumatriptan

Front 190

4 drugs causing flushing

Back 190

vancomycin
adenosine
niacin
CCBs

Front 191

3 drugs which cause torsades

Back 191

class Ia antiarrhythmics
class III antiarrhythmics
cisapride

Front 192

6 drugs which cause agranulocytosis

Back 192

clozapine
carbamazepine
colchicine
dapsone
PTU
methimazole

Front 193

5 drugs which cause aplastic anemia

Back 193

chloramphenicol
benzene
NSAIDs
PTU
methimazole

Front 194

drug causing direct coombs positive hemolytic anemia

Back 194

alpha methyldopa

Front 195

drug causing gray baby syndrome

Back 195

chloramphenicol

Front 196

drugs causing hemolysis in context of G6PD deficiency

Back 196

INH
sulfonamides
primaquine
aspirin
ibuprofen
nitrofurantoin

Front 197

drugs causing megaloblastic anemia

Back 197

pheyntoin
MTX
sulfa

Front 198

drug causing cough

Back 198

ACEI

Front 199

3 drugs causing pulmonary fibrosis

Back 199

bleomycin
amiodarone
busulfan

Front 200

drug causing acute cholestatic hepatitis

Back 200

macrolide

Front 201

4 drugs causing hepatic necrosis

Back 201

halothane
VPA
acetaminophen
amanita phalloides

Front 202

drug causing hepatitis

Back 202

INH

Front 203

2 drugs causing pseudomembranous colitis

Back 203

clindamycin
ampicillin

Front 204

6 drugs causing gynecomastia

Back 204

spironolactone
digitalis
cimetidine
alcohol
ketoconazole
estrogens

Front 205

2 drugs causing hot flashes

Back 205

tamoxifen
clomiphene

Front 206

2 drugs causing hypothyroidism

Back 206

Li
amiodarone

Front 207

2 drugs causing gout

Back 207

furosemide
thiazides

Front 208

3 drugs causing photosensitivity

Back 208

sulfonamides
amiodarone
tetracycline

Front 209

8 drugs causing Stevens-Johnson syndrome

Back 209

carbamazepine
ethosuximide
lamotrigine
phenobarbital
phenytoin
sulfa
penicillin
allopurinol

Front 210

4 drugs causing SLE-like syndrome

Back 210

hydralazine
INH
procainamide
phenytoin

Front 211

fluoroquinolones cause ___ (3) in kids

Back 211

tendonitis
tendon rupture
cartilage damage

Front 212

___ causes Fanconi's syndrome

Back 212

expired tetracycline

Front 213

Fanconi's syndrome is ___ wasting of ___ (4)

Back 213

tubular
bicarbonate
AAs
glucose
uric acid

Front 214

3 drugs causing interstitial nephritis

Back 214

methicillin
NSAIDs
furosemide

Front 215

2 drugs causing hemorrhagic cystitis
prevent this by giving ___

Back 215

CTX
ifosfamide
mesna

Front 216

2 drugs which cause cinchonism
cinchonism is ___

Back 216

quinidine
quinine

Front 217

cardiovascular aspects of cinchonism

Back 217

flushing
arrhythmia

Front 218

4 neurological sx of cinchonism

Back 218

tinnitus/hearing loss
blurry vision
somnolence
confusion

Front 219

2 cutaneous sx of cinchonism

Back 219

flushing
rash

Front 220

2 drugs causing DI

Back 220

Li
demeclocycline

Front 221

4 drugs causing PD-like syndrome

Back 221

haloperidol
chlorpromazine
metoclopramide
reserpine

Front 222

3 drugs causing seizures

Back 222

buproprion
imipinem/cilastatin
INH

Front 223

drugs causing tardive dyskinesia

Back 223

antipsychotics

Front 224

4 drugs causing disulfiram-like reaction

Back 224

metronidazole
cephalosporins (some)
procarbazine
1st generation sulfonylureas

Front 225

disulfiram-like reaction means
mechanism is ___

Back 225

feeling bad after EtOH
acetaldehyde dehydrogenase inhibition

Front 226

drug causing nephrotoxicity + neurotoxicity

Back 226

polymixins

Front 227

4 drugs causing nephrotoxicity + ototoxicity

Back 227

aminoglycosides
vancomycin
loop diuretics
cisplatin

Front 228

9 CYP450 inducers

Back 228

quinidine
barbiturates
st. john's wort
phenytoin
rifampin
griseofulvin
carbamazepine
chronic alcholism

Front 229

CYP450 inhibitors

Back 229

INH
sulfonamides
cimetidine
erythromycin
grapefruit

Front 230

3 drugs metabolized by alcohol dehydrogenase

Back 230

ethylene glycol
MeOH
EtOH

Front 231

ethylene glycol is metabolized by alcohol dehydrogenase to ___
effects are ___ (2)

Back 231

oxalic acid
acidosis
nephrotoxicity

Front 232

MeOH is metabolized by alcohol dehydrogenase to ___ (2)
effects are ___ (2)

Back 232

formaldehyde
formic acid
acidosis
retinal damage

Front 233

EtOH is metabolized by alcohol dehydrogenase to ___
effects are ___ (3)

Back 233

acetaldehyde
nausea
vomiting
hypoTN

Front 234

___ inhibits alcohol dehydrogenase

Back 234

fomepizole

Front 235

5 non-obvious sulfa drugs

Back 235

celecoxib
probenecid
thiazides
sulfonylurea
sumatriptan

Front 236

systemic part of sulfa allergic rxn

Back 236

fever

Front 237

cutaneous part of sulfa allergic rxn (3)

Back 237

rash
urticaria (hives)
Stevens-Johnson

Front 238

hematologic part of sulfa allergic rxn (3)

Back 238

HA
thrombocytopenia
agranulocytosis