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18 Cards in this Set
- Front
- Back
down syndrome associated neoplasm
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Acute Lymphoblastic Leukemia
we ALL go DOWN together |
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xeroderma pigmentosum assoc neoplasm
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squamus cell and basal cell carcinoma of skin
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chronic atrophic gastritis, pernicious anemia, and postsurgical gastic remnants assoc neoplasia
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gastric adenocarcinoma
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tuberculosis scerlosis (facial angiofibroma, seizures, mental retardation) assoc neoplasms
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astrocytoma and cardiac rhabdomyoma
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actinic keratosis assoc neoplasm
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squamous cell carcinoma of skin
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barret's esophagus assoc neoplasm
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esophageal adenocarcinoma
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plummer-vinson syndrome (atrophic glossitis, esophageal webs, anemia, all due to iron deficiency) assoc neoplasms
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squamous cell carcinoma of esophagus
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cirrhosis assoc neoplasm
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hepatocellular carcinoma
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ulcerative colitis assoc neoplasm
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colonic adenocarcinoma
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paget's disease of bone assoc neoplasm
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2ndary osteosarcoma and fibrosarcoma
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aids associated neoplasom
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aggressive malignant lymphomas (non hodgkins) and kaposi's sarcoma
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acanthosis nigricans (hyperpigmentation and epidermal thickening) assoc neoplasm
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visceral malignancy (stomach, lung, breast, uterus)
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dysplastic nevus assoc neoplasm
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malignant melanoma
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tumor associated w/ oncogenes gain of function
1 c-myc 2 bcl-2 3 erb-B2 4 ras |
1 burkitt's lymphoma
2 follicular and undifferentiated lymphomas (inhibits apoptosis) 3 breast, ovarian, and gastric carcinomas 4 colon carcinoma |
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tymor and chromosome associated w/ homozygous loss of fx of tumor suppressor genes:
1 Rb 2 BRCA1 and 2 3 p53 |
1 13q retinoblastoma, osteosarcoma
2 17q, 13q Breast and ovarian cancer 3 17p most human cancers, li-fraumeni syndrome |
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tumors assiciated w/ tumor markers:
1 PSA 2 CEA 3 AFP 4 beta-hCG 5 CA-125 6 S-100 7 alkaline phosphatase |
1 prostatic carcinoma
2 carcinoembryonic antigen. produced by 70% colorectal and pancreatic cancers, also by gastric and brast carcinomas 3 normally made by fetus. hepatocellular carcinomas. nonseminomatous germ cell tumors of the testis (i.e. ylk sac tumor) 4 hydatiform moles, choriiocarcinomas, and gestational trophoblastic tumors 5 ovarian, malignant epithelial tumors 6 melanoma, neural tumors, astrocytomas 7 metastases to bone, obstructive biliary disease, paget's disease of bone |
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tumors associated with Oncogenic viruses:
1 HTLV-1 2 HBV, HCV 3 EBV 4 HPV 5 HHV-8 |
1 adult t cell leukemia
2 hepatocellular carcinoma 3 burkitt's lymphoma, nasopharyngeal carcinoma 4 cervical carcinoma (16, 18), penile/anal carcinoma 5 kaposi's sarcoma |
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chemical carcinogens and affected organs:
1 aflatoxins, vinyl chloride 2 nitrosamines 3 asbestos 4 arsenic 5 CCl4 6 Napthalene dyes |
1 Liver
2 esophagus, stomach 3 lung (mesothelioma and bronchogenic carcinoma) 4 skin (squamus cell) 5 liver (centrilobular necrosis, fatty change) 6 bladder (transitional cell carcinoma) |