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18 Cards in this Set

  • Front
  • Back
down syndrome associated neoplasm
Acute Lymphoblastic Leukemia

we ALL go DOWN together
xeroderma pigmentosum assoc neoplasm
squamus cell and basal cell carcinoma of skin
chronic atrophic gastritis, pernicious anemia, and postsurgical gastic remnants assoc neoplasia
gastric adenocarcinoma
tuberculosis scerlosis (facial angiofibroma, seizures, mental retardation) assoc neoplasms
astrocytoma and cardiac rhabdomyoma
actinic keratosis assoc neoplasm
squamous cell carcinoma of skin
barret's esophagus assoc neoplasm
esophageal adenocarcinoma
plummer-vinson syndrome (atrophic glossitis, esophageal webs, anemia, all due to iron deficiency) assoc neoplasms
squamous cell carcinoma of esophagus
cirrhosis assoc neoplasm
hepatocellular carcinoma
ulcerative colitis assoc neoplasm
colonic adenocarcinoma
paget's disease of bone assoc neoplasm
2ndary osteosarcoma and fibrosarcoma
aids associated neoplasom
aggressive malignant lymphomas (non hodgkins) and kaposi's sarcoma
acanthosis nigricans (hyperpigmentation and epidermal thickening) assoc neoplasm
visceral malignancy (stomach, lung, breast, uterus)
dysplastic nevus assoc neoplasm
malignant melanoma
tumor associated w/ oncogenes gain of function
1 c-myc
2 bcl-2
3 erb-B2
4 ras
1 burkitt's lymphoma
2 follicular and undifferentiated lymphomas (inhibits apoptosis)
3 breast, ovarian, and gastric carcinomas
4 colon carcinoma
tymor and chromosome associated w/ homozygous loss of fx of tumor suppressor genes:
1 Rb
2 BRCA1 and 2
3 p53
1 13q retinoblastoma, osteosarcoma
2 17q, 13q Breast and ovarian cancer
3 17p most human cancers, li-fraumeni syndrome
tumors assiciated w/ tumor markers:
1 PSA
2 CEA
3 AFP
4 beta-hCG
5 CA-125
6 S-100
7 alkaline phosphatase
1 prostatic carcinoma
2 carcinoembryonic antigen. produced by 70% colorectal and pancreatic cancers, also by gastric and brast carcinomas
3 normally made by fetus. hepatocellular carcinomas. nonseminomatous germ cell tumors of the testis (i.e. ylk sac tumor)
4 hydatiform moles, choriiocarcinomas, and gestational trophoblastic tumors
5 ovarian, malignant epithelial tumors
6 melanoma, neural tumors, astrocytomas
7 metastases to bone, obstructive biliary disease, paget's disease of bone
tumors associated with Oncogenic viruses:
1 HTLV-1
2 HBV, HCV
3 EBV
4 HPV
5 HHV-8
1 adult t cell leukemia
2 hepatocellular carcinoma
3 burkitt's lymphoma, nasopharyngeal carcinoma
4 cervical carcinoma (16, 18), penile/anal carcinoma
5 kaposi's sarcoma
chemical carcinogens and affected organs:
1 aflatoxins, vinyl chloride
2 nitrosamines
3 asbestos
4 arsenic
5 CCl4
6 Napthalene dyes
1 Liver
2 esophagus, stomach
3 lung (mesothelioma and bronchogenic carcinoma)
4 skin (squamus cell)
5 liver (centrilobular necrosis, fatty change)
6 bladder (transitional cell carcinoma)