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29 Cards in this Set
- Front
- Back
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sensitivity
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SEN = TP/(TP+FN)
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specificity
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SPE = TN/(TN+FP)
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PPV
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PPV = TP/(TP+FP)
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NPV
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NPV = TN/(TN+FN)
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odds ratio
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OR = (ad/bc)
where (a,b) are exposed with + without disease (c,d) are unexposed with + without disease |
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relative risk
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RR = [a/(a + b)] / [c/(c + d)]
where (a,b) are exposed with + without disease (c,d) are unexposed with + without disease |
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attributable risk
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AR = a/(a + b) - c/(c + d)
where (a,b) are exposed with + without disease (c,d) are unexposed with + without disease |
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Henderson-Hasselbalch equation for bicarb
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pH = pKa + log( [HCO3-]/(0.03 PCO2) )
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volume of distribution (V_d)
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V_d = (amount of drug in body)/(plasma concentration)
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clearance
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CL = (rate of drug elimination)/(C_p)
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CL in terms of V_d
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CL = V_d x K_e
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t_1/2
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t_1/2 = (0.7 x V_d)/CL
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loading dose
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LD = (C_p x V_d)/F
where F is bioavailability |
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maintenance dose
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MD = (C_p x CL)/F
where F is bioavailability |
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cardiac output
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CO = SV x HR
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CO in terms of arterial-venous O2 difference
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CO = O2 consumption/(AV O2 difference)
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MAP
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MAP = CO x TPR
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MAP estimate
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2/3 DBP + 1/3 SBP
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Poiseuille resistance
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R = (8 x viscosity x length) / (pi r^4)
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clearance of substance X
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C_x = U_xV/P_x
where C_x = clearance of x, U_x = urinary concentration of x, P_x = plasma concentration of x |
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effective RPF
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ERPF = C_PAH = (U_PAH x V)/P_PAH
where C_x = clearance of x, U_x = urinary concentration of x, P_x = plasma concentration of x |
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RBF in terms of HCT
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RBF = RPF/(1-HCT)
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filtration fraction
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FF = GFR/RPF
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free water clearance
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C_H2O = V - C_Osm
where V=urine flow rate, C_Osm is total clearance of all osmoles |
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physiologic dead space
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V_D = V_T x (P_aCO2 - P_eCO2)/P_aCO2
where P_aCO2 = arterial P_CO2 P_eCO2 = expired P_CO2 |
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diffusion (V_gas) in terms of surface area
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V_gas = A/T x D_k(P_1 - P_2)
where A=surface area, T = interface thickness |
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ohm's law expression for pulmonary vascular resistance (PVR)
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PVR = (P_PA - P_LA)/CO
where P_PA = pulmonary a. pressure P_LA = L atrial pressure |
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alveolar gas equation
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P_AO2 = P_IO2 - P_ACO2/R
where P_AO2 is alveolar P_O2 P_IO2 is inspired P_O2 P_ACO2 is alveolar P_CO2 R is ratio of CO2 produced per O2 consumed (.8) |
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normal approximation for alveolar gas equation
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P_AO2 = 150 - P_ACO2/0.8
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