Step 1 Drugs

Front 1

alpha 1 receptor action, gprotein class

Back 1

increased SM contraction, increased mydriasis,
increased sphincter contraction,q

Front 2

alpha 2 receptor action, gprotein class

Back 2

decrease symapthetic outflow, decrease insulin
vasodilation-->decrease BP, i

Front 3

Beta 1 receptor action, gprotein class

Back 3

incre. HR,
incre. contractility
incre. renin release, s

Front 4

Beta 2 receptor action, gprotein class

Back 4

Vaso and Bronch dilation compensatory HR increase
decre. uterine tone, s

Front 5

M1 receptor action, grprotein class

Back 5

CNS and enteric, q

Front 6

M2 receptor action, grprotein class

Back 6

decre. HR and decre. contractility of atria, i

Front 7

M3 receptor action, g-protein class

Back 7

increase exocrine secretions, increase digestion
incre. bladder contraction
increase. bronconstrion and miosis, incre accomadation, q

Front 8

D1 receptor action, grprotein class

Back 8

relaxes renal smooth muscle, s

Front 9

D2 receptor action, grprotein class

Back 9

modulated NT release in the brain, i

Front 10

H1 receptor action, grprotein class

Back 10

incre. nasal and bronchial mucus production, contraction of bronchioloes, q

Front 11

H2 receptor action, grprotein class

Back 11

incre. gastric acid secretion, s

Front 12

V1 receptor action, grprotein class

Back 12

increased vascular SM contraction, q

Front 13

V2 receptor action, grprotein class

Back 13

increased H2O permeability, and reabsorption in the collection tubules (V2 is found in 2 kidneys), s

Front 14

Bethanechol: group, clinical application, MOA

Back 14

direct chol agonist, for post opeative ileus and urinary retention, activates the bowel and bladder

Front 15

Carbachol: group, clinical application, MOA

Back 15

direct chol agonist for glaucoma, pupilary contarction and relase of intraocular pressure,

Front 16

Pilocarpine: group, clinical application, MOA

Back 16

direct chol agonist, potent stimulator of sweat tears, and saliva, contracts cilliary mucle of eyeand pupillary sphincter

Front 17

Methacholine: group, clinical application, MOA

Back 17

direct chol agonist, challenge test for asthma, stims muscarinic receptors in airway

Front 18

Neostigmine: group, clinical application, MOA

Back 18

anticholinesterase, for post op neurogenic ileus and urinary retenion help myastheni gracis and reverse NMJ blockade-No CNS peneatrion

Front 19

Pyridostigmine: group, clinical application, MOA

Back 19

anticholinesterase, for long acting myasthenia gravis, no CNS penetation

Front 20

Edrophonium: group, clinical application, MOA

Back 20

anticholinesterase, extrememly short acting for diagnosis of myasthenia gravis

Front 21

Physostigmine: group, clinical application, MOA

Back 21

glaucome and atropine overdose, crosses

Front 22

Ecothiophate: group, clinical application, MOA

Back 22

anticholinesterase, glaucome

Front 23

Name 3 types of achE inhibitor poisoning

Back 23

organophosphates, parthion and insectisides

Front 24

Name antidose to AchE inhibition poison:

Back 24

pralidoxime regenerates AchE and atropine for symptomatic relief

Front 25

Atropine hometropine and tropicamde: drug type, where do they act, clinical application

Back 25

work in the eye to produce mydriasis and cycloplegia

Front 26

Benzotropine: drug type, where do they act, clinical application

Back 26

muscarinic antagonist, work in the CNS, used to decrease PD Park my Benzz symptoms

Front 27

Scopolamine: drug type, where do they act, clinical application

Back 27

muscarinic antagonist used for motion sickness

Front 28

oxybutyin: drug type, where do they act, clinical application

Back 28

genitourinary, reduces urgency in mild cystitis, reduce bbladder spasms

Front 29

Methacoplamine and propantheline: drug type, where do they act, clinical application

Back 29

muscarininc antagonist: gi, for peoptic ulcer treatment

Front 30

Atropine: drug type, where do they act, clinical application, eyes, airway, stomachie, gut, bladder toxicity

Back 30

muscarinic antagonist, dilates pupils, deccreases secreion,s decreases motility, decreases urgency, can cause paralysis of the mucles of the cilliary body (cycloplegia)->no accomadation

Front 31

Hexamethonium: drug type, where do they act, clinical application

Back 31

nicotinic antagonist, put a hex on nicotine users, ganglionic blocker to prevent vagal reflex responses to changes in BP

Front 32

epinephrine: drug type, where do they act, clinical application

Back 32

sympathomimetic, a1 a2 b1 b2, anaphylaxis, open angle glaucoma, asthma, hyopotension

Front 33

NE: drug type, where do they act, clinical application

Back 33

sympathomimetic, a1 a2>b1, treats hypotension, but decreases renal perfusion

Front 34

Isoproterenol: drug type, where do they act, clinical application

Back 34

sympathomimetic, b1=b2 used for av block

Front 35

Dopamine: drug type, where do they act, clinical application

Back 35

D1=D2, shock and increases renal perfusion, for heart failure

Front 36

Dobutamine: drug type, where do they act, clinical application

Back 36

sympathomimetics with b1>b2 for cardiogenic shock, stress testing

Front 37

Metaproterenol, Albuterol, salmeterol, terbutaline Levalbuterol (no b1) MAST

Back 37

selective B2>>B1, asthma except terbutaline reduces premature uterine contractions

Front 38

Ritodrine: drug type, where do they act, clinical application

Back 38

B2 agoonist, that reduces premature uterine contractions

Front 39

Amphetamine:: drug type, where do they act, clinical application

Back 39

indirect sympathomimetic, releases stored catecholamines,

Front 40

ephedrine:: drug type, where do they act, clinical application

Back 40

indirect sympathomimetic for nasal congestion, treats urinary incontence and hypotension

Front 41

cocain: drug type, where do they act, clinical application

Back 41

indirect sympathomimetic: cocain vasocontrin, local anesthisa,

Front 42

Sympathoplegics: clonidine, alpha-methyldopa

Back 42

centrall acting alpha 2 agonist to decrase adrrneargic outflow, treats HTN, good for renal HTN

Front 43

Phenoxybenzaimine(irreversible /noncomp) and phentolamine: drug type, where do they act, clinical application

Back 43

nonselective alpha blocker, for treating pheochromoctyoma

Front 44

Prazosin terazosin and doxazosin: drug type, where do they act, clinical application, SE

Back 44

alpha1 blockers,teats htn and urinary renteion BPH, first dose can cause orthostatic hypotension

Front 45

Mirtazapine: drug type, where do they act, clinical application

Back 45

alpha2 blocker used to treat depression

Front 46

Name 6 uses of OlOL

Back 46

HTN, angina pectoris, MI, SVT, (propanololl and esmolol)CHF, glaucome (timolol)

Front 47

Name 2 nonselctive beta and alpha antagonits

Back 47

carvedilol and labetalol

Front 48

Name 2 partial beta agonists

Back 48

pindolol and acebutolol