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48 Cards in this Set

  • Front
  • Back
alpha 1 receptor action, gprotein class
increased SM contraction, increased mydriasis,
increased sphincter contraction,q
alpha 2 receptor action, gprotein class
decrease symapthetic outflow, decrease insulin
vasodilation-->decrease BP, i
Beta 1 receptor action, gprotein class
incre. HR,
incre. contractility
incre. renin release, s
Beta 2 receptor action, gprotein class
Vaso and Bronch dilation compensatory HR increase
decre. uterine tone, s
M1 receptor action, grprotein class
CNS and enteric, q
M2 receptor action, grprotein class
decre. HR and decre. contractility of atria, i
M3 receptor action, g-protein class
increase exocrine secretions, increase digestion
incre. bladder contraction
increase. bronconstrion and miosis, incre accomadation, q
D1 receptor action, grprotein class
relaxes renal smooth muscle, s
D2 receptor action, grprotein class
modulated NT release in the brain, i
H1 receptor action, grprotein class
incre. nasal and bronchial mucus production, contraction of bronchioloes, q
H2 receptor action, grprotein class
incre. gastric acid secretion, s
V1 receptor action, grprotein class
increased vascular SM contraction, q
V2 receptor action, grprotein class
increased H2O permeability, and reabsorption in the collection tubules (V2 is found in 2 kidneys), s
Bethanechol: group, clinical application, MOA
direct chol agonist, for post opeative ileus and urinary retention, activates the bowel and bladder
Carbachol: group, clinical application, MOA
direct chol agonist for glaucoma, pupilary contarction and relase of intraocular pressure,
Pilocarpine: group, clinical application, MOA
direct chol agonist, potent stimulator of sweat tears, and saliva, contracts cilliary mucle of eyeand pupillary sphincter
Methacholine: group, clinical application, MOA
direct chol agonist, challenge test for asthma, stims muscarinic receptors in airway
Neostigmine: group, clinical application, MOA
anticholinesterase, for post op neurogenic ileus and urinary retenion help myastheni gracis and reverse NMJ blockade-No CNS peneatrion
Pyridostigmine: group, clinical application, MOA
anticholinesterase, for long acting myasthenia gravis, no CNS penetation
Edrophonium: group, clinical application, MOA
anticholinesterase, extrememly short acting for diagnosis of myasthenia gravis
Physostigmine: group, clinical application, MOA
glaucome and atropine overdose, crosses
Ecothiophate: group, clinical application, MOA
anticholinesterase, glaucome
Name 3 types of achE inhibitor poisoning
organophosphates, parthion and insectisides
Name antidose to AchE inhibition poison:
pralidoxime regenerates AchE and atropine for symptomatic relief
Atropine hometropine and tropicamde: drug type, where do they act, clinical application
work in the eye to produce mydriasis and cycloplegia
Benzotropine: drug type, where do they act, clinical application
muscarinic antagonist, work in the CNS, used to decrease PD Park my Benzz symptoms
Scopolamine: drug type, where do they act, clinical application
muscarinic antagonist used for motion sickness
oxybutyin: drug type, where do they act, clinical application
genitourinary, reduces urgency in mild cystitis, reduce bbladder spasms
Methacoplamine and propantheline: drug type, where do they act, clinical application
muscarininc antagonist: gi, for peoptic ulcer treatment
Atropine: drug type, where do they act, clinical application, eyes, airway, stomachie, gut, bladder toxicity
muscarinic antagonist, dilates pupils, deccreases secreion,s decreases motility, decreases urgency, can cause paralysis of the mucles of the cilliary body (cycloplegia)->no accomadation
Hexamethonium: drug type, where do they act, clinical application
nicotinic antagonist, put a hex on nicotine users, ganglionic blocker to prevent vagal reflex responses to changes in BP
epinephrine: drug type, where do they act, clinical application
sympathomimetic, a1 a2 b1 b2, anaphylaxis, open angle glaucoma, asthma, hyopotension
NE: drug type, where do they act, clinical application
sympathomimetic, a1 a2>b1, treats hypotension, but decreases renal perfusion
Isoproterenol: drug type, where do they act, clinical application
sympathomimetic, b1=b2 used for av block
Dopamine: drug type, where do they act, clinical application
D1=D2, shock and increases renal perfusion, for heart failure
Dobutamine: drug type, where do they act, clinical application
sympathomimetics with b1>b2 for cardiogenic shock, stress testing
Metaproterenol, Albuterol, salmeterol, terbutaline Levalbuterol (no b1) MAST
selective B2>>B1, asthma except terbutaline reduces premature uterine contractions
Ritodrine: drug type, where do they act, clinical application
B2 agoonist, that reduces premature uterine contractions
Amphetamine:: drug type, where do they act, clinical application
indirect sympathomimetic, releases stored catecholamines,
ephedrine:: drug type, where do they act, clinical application
indirect sympathomimetic for nasal congestion, treats urinary incontence and hypotension
cocain: drug type, where do they act, clinical application
indirect sympathomimetic: cocain vasocontrin, local anesthisa,
Sympathoplegics: clonidine, alpha-methyldopa
centrall acting alpha 2 agonist to decrase adrrneargic outflow, treats HTN, good for renal HTN
Phenoxybenzaimine(irreversible /noncomp) and phentolamine: drug type, where do they act, clinical application
nonselective alpha blocker, for treating pheochromoctyoma
Prazosin terazosin and doxazosin: drug type, where do they act, clinical application, SE
alpha1 blockers,teats htn and urinary renteion BPH, first dose can cause orthostatic hypotension
Mirtazapine: drug type, where do they act, clinical application
alpha2 blocker used to treat depression
Name 6 uses of OlOL
HTN, angina pectoris, MI, SVT, (propanololl and esmolol)CHF, glaucome (timolol)
Name 2 nonselctive beta and alpha antagonits
carvedilol and labetalol
Name 2 partial beta agonists
pindolol and acebutolol