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26 Cards in this Set

  • Front
  • Back
Risk Factors for STDs
-number of sexual partners
-Unrpotected sex
-Age
-Sexual preference
-Prostitution
-Illicit drug use
Gonorrhea: Microbiology
-Neisseria gonorhoeae
-Gram negative diplococcus
-Grows best in warm, mucus secreting epithelia
-Ports of entry
Genitourinary tract
Eyes
Oropharynx
Anorectum
Skin
Gonorrhea: pathophysiology
1)Gonococci attach to cell membranes by surface pili
2)Pinocytosis occurs followed by mucosal damage
3)Polymorphonuclear (PMN) leukocytes invade the tissue
4)Submucosal abscesses form and purulent exudates (pus) are secreted
Chlamydia: Pathophysiology
1) Uptake of chlamydia EBs
2) Initial inclusions
3) Fusion of inclusions; appearance of RBs
4) RBs eithergo back to EBs or go on with infection
Chlamydia: Microbiology
-Chlamydia tracomatis
-Intracellular gram negative
Require material from host to reproduce
Maintain cellular identity throughout development
Syphilis: Microbiology
Caused by a spirochete
-Trepenoma pallidum
Syphilis: Pathophysiology
1) Typically spread by sexual contact with enfected mucus membranes or skin lesions
2) T. pallidum penetrates intact mucus membrane or break in epithelium
3) Spirochetes enter blood
HSV: microbiology
Type 1 - cold sores
Type 2 - genital herepes

-Transmitted by
Urethra, oropharynx, cervix, conjunctivae, or abraded skin
HSV: pathophysiology
-Replicates in skin and mucus membranes

5 stages:
1)Primary mucocutaneous infection
2)Infection of the ganglia
3)Establishment of latency
4)Reactivation
5)Recurrent infection
Trichomoniasis: microbiology
-Trichomonas vaginalis
-Flagellated,motile protozoan
-Most commonly spread through sexual contact
-May survive on moist surfaces up to 45 mins
-More common in females than males
Trichomoniasis: pathophysiology
1)Trichomonads attach to vaginal or urtethral mucosa
2)Elicit an inflammatory response
3)Manifests as discharge containing large numbers of PMN leukocytes
Which STD is a diplococcus?
Gonorrhea
This STD has infective ERs and reproductive RBs
Chlamydia
Chancre
Primary syphilis
This stage of _______ infects multisystems
Secondary syphilis
These two STDs can infect the CNS
Syphilis and HSV
This STD can cross the placenta
Syphilis
Nontreponemal
Not specific testing for syphilis
Treponemal
Specific testing for syphilis
Seronegative
Primary 1st episode
Seropositive
non-primary 1st episode
Prodrome
HSV - itching, burning, or tingling at the site of future lesions
Neonatal herpes
-High morbidity and mortality
-May lead to permanent neurologic damage
Flagellated
Trichomoniasis
Malodorous, vaginal discharge
Trichomoniasis
Increases pH
Trichomoniasis