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36 Cards in this Set

  • Front
  • Back

Inductive Reasoning

Specific -> general



Start with observations, put them together to form a theory

Deductive Reasoning

General -> specific



Start with a theory, then use verification

5 steps of choosing a research topic

1. What am I interested in?


2. Find a "research problem"


3. Carefully state research problem


4. Develop this into a hypothesis


5. Determine feasibility of hypothesis

2 main theories of epistimology

Positivism


Constructivism

Reality is :



objective and singular


separate from the observer


value-free and unbiased

Positivism

No fixed reality, everything is subjective


Things are what we make them to be


Heisenberg's Uncertainty Principle

Constructivism

What is Triangulation?

Using both qualitative and quantitative reasoning to answer a research question

Descriptive research

Describe populations

Exploratory research

Find relationships

Experimental

Cause and Effect



RCT- true experiments

What is post-positivism?

Compromise


Reality is singular but viewed through subjective eyes

Do quantitative and qualitative research use logic or empiricism?

Both

What is empiricism?

Verification through observation or experience


Can be quantitative or qualitative


(does NOT mean quantification)

What are the 4 aspects of the scientific method?

Universality


Reproducibility


Control


Measurement

What type of research is a survey?

Prospective


Collects objective and subjective info


Most common method of research

What is a literature review?

A comprehensive overview of what is known about a topic


More than one article, usually published

What is the purpose of a literature review?

To set the stage for a research project


To support an evidence-based practice

Components of Evidence Based Practice

Best available evidence in:


Literature


Clinical Experience


Patient preferences in the process

How are clinical questions constructed?

PICO:


Population


Intervention


Comparison


Outcome

Generalized database vs specialized

Gen: PubMed


- Pro: comprehensive


- Con: not selective for quality



Spec: Cochrane


- Pro: Best pre-appraised quality


- Con: highly selective

Sackett's Classification of Studies

I- Large RCT, Systematic Reviews


II- Smalled RCT


III- Not randomized, concurrent cohort comparisons with/without tx


IV- Nonrandomized historical cohort comparisons bt current subjects who did received the intervention and former subjects who did not. Case controls


V- Case studies w/o controls- expertise

Best type of research using Sackett's classification

Class I

Appraisal Rating system of literature review

Grade A: Supported by ≥1 Level I studies



Grade B: Supported by ≥1 Level II study



Grade C: Supported by level III, IV or V studies

What happened during the Nazi war crimes?

Sterilization experiments

What was one of the first codes to be written to prevent harm to research participates?

Nuremberg Code

What occurred during the Jewish chronic disease hospital study?

Developed info on the nature of the human transplant rejection process, 1963


Involve the injection of live cancer cells into pts who were hospitalized with various chronic debilitating diseases

What occurred during the Willowbrook Study?

1963-1966, Willowbrook state school, "mentally defective persons"


Subjects (all children) were deliberately infected with the hepatitis virus- via feces, later serum

What occurred during the radiation tests on mentally impaired boys?

1946-1956, 19 boys were fed radioactive milk by researchers who wanted to learn more about the digestive system


Fed radioactive forms of iron and calcium to the boys to study the body's ability to digest minerals

What was the first set of ethical guidelines written by researchers and physicians in 1964?

Declaration of Helsinki

What is the significance of the Beecher: "Ethics of Clinical Research" article written in 1966?

Was published in the New England Journal of Medicine; documented to the research community the unethical human research that had been performed


*A neutral person should be overlooking research and approve

When was the Belmont report published?

1978

What is the minimum number of people on an IRB board?

5

Ex: Want to measure area of a room. Using measurement of length and width (Face/Content, Criterion, Construct, Internal/External Validity)

Construct Validity

Ex: Want to know if new shoes will be popular. Survey a group of people at the mall (Face/Content, Criterion, Construct, Internal/External Validity)

Internal/External Validity

Ex: Want to measure popularity. Use Facebook to create the "P scale" (Face/Content, Criterion, Construct, Internal/External Validity)

Criterion Validity

Ex: Want to measure cardiac health. Use blood pressure cuff (Face/Content, Criterion, Construct, Internal/External Validity)

Construct Validity


Face validity