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13 Cards in this Set

  • Front
  • Back
Define pulsus paradoxus
An inspiratory drop in systolic BP of greater than 10mmHg
Define a pansystolic murmur and what three pathologies this can indicate.
Sustained pressure throughout systole

Mitral regurgitation
Tricuspid regurgitation
Ventricular septal defect
What can an systolic 'ejection' murmur indicate?
1. outflow obstruction - AS, PS
2. high output murmurs - anaemia, thyrotoxicosis, pregnancy, fever.
Where are the main sites of production of ALPs?
liver
bone
kidney
GIT
placenta
What does a cholestatic picture (on LFTs) look like?
ALP - High
GGT - High
AST/ALT - raised a little
What does a hepatitic picture (on LFTs) look like?
AST/ALT - High
GGT and ALP - raised a little
Alcohol does what to LFTs?
Raises GGT
What are the two Bacillus species often associated with human disease?
B. anthracis (G+)
B. cereus (G+)

They are facultative anaerobes (ie can use respiration or fermentation)
What is an eschar?
A skin lesion associated with cutaneous anthrax and resembles a black necrotic sore.
When is the use of metronidazole indicated?
anaerobic bacteria and protozoa infections.
What is a key feature of obligate anaerobes such as clostridium, bacteriodes and actinomyces?
They lack catalase and/or superoxide dimutase activity therefore they are susceptible to oxidative damage.
Which four species of bacteria would be included in a differential diagnosis of acute gastroenteritis?
Salmonella
Shigella
Yersinia
Campylobacter

(all are G-)
What dermatomes does heart pain refer to?
T1-T5

(pain fibres travel with sympathetic nerves)