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30 Cards in this Set
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- Back
- 3rd side (hint)
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Quick relief or
long term control? B2 agonists |
Quick
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Quick relief or
long term control? Ipratropium |
Quick
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Quick relief or
long term control? O2 |
Quick
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Short term
or long term control? Systemic steroids |
SHORT
term |
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Quick relief or
long term control? Inhaled corticosteroids |
Long
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Quick relief or
long term control? Cromolyn |
Long
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Quick relief or
long term control? Antileukotrienes |
Long
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Quick relief or
long term control? Theophylline |
Long
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Quick relief or
long term control? Omalzumab |
Long
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Anti-inflammatory
Maximal response achieved in 8 weeks Most efficacious anti-inflammatory Rx for asthma used as long-term control for moderate to severe asthma sometimes used for mild. |
Inhaled Corticosteroids
Name them? 3ct What 2 conditions are they used for ? |
-Beclomethasone -Budesonide -Fluticasone for Asthma & COPD |
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Adverse effects:
Thrush (oral candidiasis) No evidence of stunted growth in children. |
Cortico Steroids
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For inhaled quick-relief medicine
(beta2-agonists) wait about how long between puffs? There is no need to wait between puffs for other medicines. |
One minute
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If you are using a steroidal inhaler
you need to |
Rinse and spit your mouth after each use to prevent getting an oral infection.
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Modulate mast cell mediator release
& Modulate Eosinophil recruitment & Inhibit both early and late Asthmatic responses to Allergen challenge & exercise-induced bronchospasm. 2ct |
Mast cell stabilizers for
Asthma Cromolyn Sodium Nedocromil |
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Cromolyn sodium
& Nedocromil can be effective when taken before an exposure or exercise but These Rx do not.....?? |
Relieve asthmatic symptoms
once present. |
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These organisms contribute to
airway obstruction and asthma symptoms by contracting airway smooth muscle increasing vascular permeability and mucus secretion and attracting and activating airway inflammatory cells. |
Leukotrienes
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Cause modest improvements in lung function
& reductions in asthma symptoms & lessen the need for rescue therapy. |
Leukotriene modifiers
Montelukast |
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Churg-Strauss syndrome
has been diagnosed in a small number of patients although this is suspected to be an effect of: corticosteroid withdrawal as opposed to a direct drug effect. What Class? What specific Rx: |
Leukotriene modifiers
Rx = Montelukast Is It a corticosteroid Y/N? |
Yes
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-This class of Rx are Not recommended for daily Use
-Increased use (more than one canister a month) or -Lack of expected effect indicates diminished asthma control and dictates the need for additional long-term control therapy |
Short-acting
beta 2 Agonists |
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Particularly useful in preventing
nocturnal asthmatic attacks Inhibits late phase of allergen -induced bronchoconstriction which occurs after bronchodilation effects of shorter acting drugs have dissipated. |
Long-acting beta2-agonists
salmeterol and formoterol Used long term for what Dz 2ct |
Long-term tx of
asthma & emphysema (Brenner p. 307) |
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This combo inhaler
has shown efficacy in both maintenance & rescue Give ?Rx? short time prior to onset or ?Rx? Both Drugs are for Pts not controlled w Inhaled Steroids. |
Formoterol
Budesonide +info |
give formoterol short time to onset
Both are for patients not controlled on inhaled steroids. |
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Fluticasone
Salmeterol & Budesonide Formoterol are used for patients who are not controlled on? |
Inhaled steroids
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Inhibition of phosphodiesterase (PDE) isozymes that catalyze the degradation of c-Amp
Antagonism of adenosine receptors Inhibition of calcium influx Enhancement of catecholamine secretion Anti-inflammatory and immunomodulating effects |
Theophylline
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Used for moderate to severe COPD
asthma apnea dyspnea Increases diaphragmatic contractility improves exercise performance and sense of well-being for patients |
Theophylline
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Has several drug interactions
Including: Cimetidine Erythromycin Fluoroquinolones Isoniazid Verapamil |
Theophylline
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Symptoms less than 2 days a week
night awakenings 2 x a month beta 2 use 2 days a week what class of asthma severity? What step? |
Intermittent
step one |
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What are the drugs in each step in the asthma plan?
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MILD:
Low dose ICS MODERATE: Low-Dose ICS + LABA2 Or Medium-Dose ICS & Consider Short Course OCS (Oral Cortico-Steroid) SEVERE: Medium-Dose ICS + LABA2 Or Hi-Dose ICS + LABA2 & Consider Shrt Course OCS Name the 3 ICS? |
ICS =
Beclomethasone Budesonide Fluticasone |
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more than 2 days a week symptoms
3-4 night awakenings/mo Minor activity limitation No more than 1 beta-2/day What class? What step? |
Mild
step 2 |
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Daily symptoms
more than one night awakening a week some limitations to activity What class? What step? |
Moderate
step 3 |
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Attacks throughout the day
often nightly awakenings extremely limiting What class? What step? |
Severe
Step 4 5 6 |
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