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15 Cards in this Set

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What are the Mechanical and Physiological functions of bone?

Mechanical = structural & protective




Physiological = Ca2+ regulation, Blood cell production in bone marrow.

Organic (35%) and inorganic (65%) make up bone but what is each component made up of?

organic = Cells (osteoblasts, lining cells, osteocytes and osteoclasts)


Matrix ( mostly type 1 collagen)




Inorganic = Mineral content (hydroxyapatite - makes the bone strong)

Long bone consists of....?

Diaphysis (shaft)




2 Epiphyses

What are the two different types of bone?

1. Cortical or Compact



2. Cancelous, spongy or trabecular



Cortical or compact bone makes up the external region of bone, what are its functions?

80% of bone mass




External surfaces of bone




Walls of Diaphysis (shafts)




Principally mechanical function

Cancellous or trabecular bone makes up the internal region of bone, what are its functions?

- 20% of bone mass


- Lattice of fine body plates


- Epiphyses of long bones, vertebral bodies & flat bones


- Intercommunicating spaces in mesh filled with bone marrow


- Reduces skeletal mass without comprising strength

What are the material properties of bone?

Properties are independent of specimen.




i.e. stress at which a sample of cortical bone breaks under compression.

What are the structural properties of bone?

Properties are independent of specimen.




i.e. breaking force for tibia.


Compression / tension

What is included in the longitudinal growth process?

Endochnodral ossification




Primary ossification centre




Secondary ossification centre (epiphyseal plates)




Ceases when secondary growth plates fuse at adulthood

What is included in the circumferential growth process?

Diameter increases throughout lifespan




rapid prior to adulthood then very slow

What is included in the skeletal process of bone repair?

Haemotoma leads to clot formation




Cartilage fills gap which is ossified to form new woven bone (callous)




Callous then remodels over time

What is included in the skeletal process of bone remodelling?

Bone mass is maintained, increased & decreased




Continuous repair of micro-damage




Ensures bone is fit for purpose




Functional adaptation

Micro-damage and sensory feedback from bone initiate the remodelling process.




What 2 cells are involved in the remodelling process?

Osteoclasts = bone resorption




Osteoblasts = bone formation

Why does bone fracture occur?

If the stress of the bone exceeds the strength of the material.




Can be through;


- excessive forces


- weak material


- cumulative damage due to repetitive loading

What are the 8 types of Fracture?

1. Complete or Incomplete


2. Transverse


3. Spiral


4. Comminuated


5. Avulsed


6. Impacted


7. Greenstick


8.Compression