Spom Exam 2 - Musculoskeletal Pathology (Randomized)

Front 1

Major causes of dwarfism

Back 1

ACHONDROPLASIA

Front 2

40-50 years old, outward bone growth of flat bones of skull and face, and may protrude into sinuses

Back 2

OSTEOMAS

Front 3

Abnormal development of type I collagen

Back 3

OSTEOGENESIS IMPERFECTA

Front 4

Activates osteoclasts and thus bone resorption and Calcium mobilization

Back 4

PARATHYROID HORMONE

Front 5

Associated with Gardner’s syndrome and May cause cosmetic problems; Benign

Back 5

OSTEOMAS

Front 6

Bacteria involved in Osteomyelitis?

Back 6

mostly staphlococcus aureus,may be e.Coli, klebsiella or proteus

Front 7

Blue sclera

Back 7

OSTEOGENESIS IMPERFECTA

Front 8

Bone resorption and Replacement of bone by loose connective tissue

Back 8

HYPERPARATHYROIDISM

Front 9

Boney trabeculae thinner and more widely separated

Back 9

OSTEOPOROSIS

Front 10

Brittle bone disease

Back 10

OSTEOGENESIS IMPERFECTA

Front 11

Brodies abscess of Chronic Osteomyelitis results in?

Back 11

Abscess surrounded by sclerotic bone

Front 12

Calcium and Vitamin D needed to prevent

Back 12

OSTEOPOROSIS

Front 13

Cancerous bone tumor that arises from osteoblasts. Most common in long bones like tibia and femur

Back 13

OSTEOID OSTEOMA

Front 14

Codman's triangle occurs with what condition?

Back 14

OSTEOSARCOMA

Front 15

Condition that has cap of cartilage growing from surface of bone underneath and affects metaphysis, lower femur, upper tibia, and humerus

Back 15

OSTEOCHONDROMA

Front 16

Decrease in bone mass

Back 16

OSTEOPOROSIS

Front 17

Decreased serum calcium or phosphate and decreased levels of vit D

Back 17

OSTEOMALACIA-RICKETS

Front 18

Effects femoral necks and vertebrae

Back 18

OSTEOPOROSIS

Front 19

Elevation of Periosteum is called?

Back 19

Codman's Triangle

Front 20

Enlargement of head: headaches, visual disturbances and deafness

Back 20

Paget's Disease

Front 21

estrogen deficiency may increase bone loss and decrease bone synthesis

Back 21

OSTEOPOROSIS

Front 22

Genetic factors: VDR molecule

Back 22

OSTEOPOROSIS

Front 23

Grows in opposite direction of joint?

Back 23

OSTEOCHONDROMA

Front 24

High levels of prostoglandin pain relieved by aspirin

Back 24

OSTEOID OSTEOMA

Front 25

Impaired maturation of cartilage in the developing growth plate

Back 25

ACHONDROPLASIA

Front 26

In children with open epiphyseal plates produces cup shaped deformity on x ray and Accumulation of unmineralized bone by defective mineralization

Back 26

OSTEOMALACIA-RICKETS

Front 27

Increased resorption of calcium by renal tubules

Back 27

PARATHYROID HORMONE

Front 28

Increased synthesis of vitamin D

Back 28

PARATHYROID HORMONE

Front 29

Intravenous Drug Users often get osteomyelitis from what condition?

Back 29

Pseudomonas

Front 30

Involucrum of Chronic Osteomyelitis results in?

Back 30

Necrosis of Rim of reactive bone

Front 31

Large central nidus in spine and large bones of legs. Often painless

Back 31

OSTEOBLASTOMA

Front 32

Loss of bone

Back 32

OSTEOPOROSIS

Front 33

Malignant cells form osteoid, that extend from marrow to cortex to soft tissue to epiphysis to joint

Back 33

OSTEOSARCOMA

Front 34

May destroy preexisting bone or grow around it; metastasizes via blood most commonly in lung. May spread to other bones. Lymph nodes almost never involved

Back 34

OSTEOSARCOMA

Front 35

MAY DEVELOP SECONDARY OSTEOSARCOMAS

Back 35

Paget's Disease

Front 36

May have satellite nodules with what condition?

Back 36

OSTEOSARCOMA

Front 37

Mixed phase of paget's disease causes?

Back 37

Bone resorption and bone formation (Osteoclasts and osteoblasts)

Front 38

More common in males; 10-30 years old. Radiolucent nidus in central bone of femur, tibial metaphysis

Back 38

OSTEOID OSTEOMA

Front 39

Most asymptomatic and common benign tumor of bones; may spontaneously regress; Multiple may be associated with Gardner's syndrome

Back 39

OSTEOCHONDROMA

Front 40

Most common in england, australia, and north europe

Back 40

Paget's Disease

Front 41

Most common primary bone malignancy; More common in males

Back 41

OSTEOSARCOMA

Front 42

Multiple bone fractures and Multiple bone fractures

Back 42

OSTEOGENESIS IMPERFECTA

Front 43

Neutrophilic inflammation and necrosis

Back 43

Acute Osteomyelitis

Front 44

Newborns often get osteomyelitis from what condition?

Back 44

H. Influenza

Front 45

Occurs in patients over 55 years old and affects lumbar sacral area, spine, pelvis, femur, or skull

Back 45

Paget's Disease

Front 46

Osteolytic phase of paget's disease causes?

Back 46

Marrow replaced by connective tissue with osteoclasts. (Osteoclasts)

Front 47

Osteomyelitis associated with Tuberculosis is also called?

Back 47

Pott's Disease

Front 48

Osteosclerotic phase of paget's disease causes?

Back 48

irregular bone deposition causing a mosaic pattern (osteoblasts)

Front 49

Paget's Disease often causes what other condition?

Back 49

Secondary peak of OSTEOSARCOMA

Front 50

Possible viral etiology

Back 50

Paget's Disease

Front 51

Primary : autonomous secretion and Secondary: chronic renal insufficiency

Back 51

HYPERPARATHYROIDISM

Front 52

Sequestrum of Chronic Osteomyelitis results in?

Back 52

Residual necrotic bone

Front 53

Shortening of proximal extremities bowing of legs and lordosis

Back 53

ACHONDROPLASIA

Front 54

Sickle cell patients often get osteomyelitis from what condition?

Back 54

Salmonella

Front 55

Structural changes lead to increased bone fragility

Back 55

OSTEOPOROSIS

Front 56

Subperiosteal abscesses or disruption of blood supply that can spread to joint capsule

Back 56

Acute Osteomyelitis

Front 57

This condition can occur via hematogenous spread, direct extension from joint or tissue or traumatic injury from surgery or trauma

Back 57

Osteomyelitis

Front 58

Transverse fracture of long bones

Back 58

Paget's Disease

Front 59

Usually asymptomatic; Serum alkaline phosphatase elevated from osteoclasts activity; Hypervascular bone lesions: warm skin, increased cardiac output

Back 59

Paget's Disease

Front 60

Usually occurs in 10-25 year olds with second peak after 40; Located in metaphysis, lower femur and upper tibia

Back 60

OSTEOSARCOMA

Front 61

What are other preexisting conditions of Osteosarcoma? Radiation:? Chemotherapy:? Trauma:?

Back 61

Radiation: 10 years post radiation high grade; Chemotherapy: children with retinoblastoma; Trauma does not cause but brings attention to it

Front 62

What is the main preexisting conditions of Osteosarcoma?

Back 62

Paget's Disease