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10 Cards in this Set
- Front
- Back
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Inheritance and gene of ichthyosis vulgaris
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AD; unknown
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What is the defect in ichthyiosis vulgaris?
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defect in profilaggrin - > decreased levels in keratinocytes
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T/F scale in ichthyiosis vulgaris typically involves flexures.
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False - spares flexures with increased involvement of extensors
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What % of icthyiosis vulgaris patients have atopic derm?
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50% +
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Where do you biopsy ichthyiosis vulgaris and what do you find?
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anterior shin
absent granular layer |
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EM finding of ichthyiosis vulgaris
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small poorly formed keratohyaline granules
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Skin findings in ichtyiosis vulgaris besides scale.
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KP
hyperlinear palms |
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Eponym for X linked ichthyiosis and gene defect
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steriod sulfatase deficincy
also known as arylsulfatase |
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Name the Cs of X linked ichhthyiosis
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comma shaped corneal opacities (50%)
c/s Cryptochorchism (20%) |
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Pts with X linked ichthyiosis may be at increased risk of what malignancy?
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testicular ca
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