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45 Cards in this Set

  • Front
  • Back
What is the effect of an excess amount of Pituitary Growth Hormone (GH)?
• children - leads to gigantism (the rate of growth increases and the time period increases)

• adults - acromegaly (increase in size of wrist, ankle, mandible, and nose)
What is the effect of a deficit in Pituitary Growth Hormone (GH)?
• children - leads to dwarfism
What are the 6 types of trauma and injury to bone (fracture)?
1. Simple
2. Compound
3. Comminuted
4. Compression
5. Avulsion
6. Greenstick
Simple Fracture
Bone broken but not displaced
Compound Fracture
Bone breaks through the skin
Comminuted Fracture
A complete break, but the bone is fragmented (many small pieces)
Compression Fracture
Bone collapses under compressive forces or telescopes into itself (common in the vertebrae)
Avulsion Fracture
Tendon or ligament pulls bone away at the site of attachment
Greenstick
• Incomplete fracture (not all the way through) and bending of the bone.

• the break and the bend are on opposite sides

• Common in children
What are the 5 steps of the healing of a fracture?
1. Fracture hematoma (blood clot) forms from the ruptured/severed blood vessels

2. A soft callus forms(mixture of spongy bone and fibrocartilage)

3. A hard callus forms by mineralization of soft callus (ossification)

4. Remodeling of hard callus to mature bone (i.e. compact and spongy)
Spongy bone is made by:
Osteoblast
Fibrocartilage is made by:
Fibroblasts brought in by blood vessels
After remodeling a bulge is present. What does this tell the body?
That it is a weak area.
Osteitis
Inflammation of bone tissue caused by injury or infection
What are the two types of Osteitis?
Periostitis and Osteomyelitis
What is the difference between Periostitis and Osteomyelitis?
Periostitis: inflammation of periosteum caused by trauma or infection (exterior, scoring or pitting)

Osteomyelitis: Inflammation of bone interior caused by bacteria, usually initially entering the bone via wound or via bloodstream (interior, destruction of spongy bone from the inside out)
Tuberculosis
Can spread to the spongy bone (particulary of the vertebral bodies), resulting in bone and joint destruction
What are neoplasms?
Tumors, out of control growth
What are the four types of bone neoplasms and are they benign or malignant?
Benign: Osteochondroma and Osteoma

Malignant: Osterogenic sarcoma (osteosarcoma), multiple myeloma
What is the difference between benign and malignant?
Benign - not lethal

Malignant - lethal
What effect can aging have on bone?
Osteoporosis
What is osteoporosis?
The reduction in bone mass due to deossification, most prevalent in middle aged and elderly women (post menopausal)
When someone has osteoporosis what specifically happens to the bone?
• Thinning of the trebecule (spongy bone)

• The osteoclasts break down boney connective tissue faster than the osteoblasts can build them
Why is osteoporosis prevalent in middle-aged and elderly women?
• women have less bone mass than men

• women lose bone mass sooner (age 35) and faster than med do

• by menopause women lose 25 - 35% bone, it doesn't happen to men until 60 or later
Which of the following 3 contribute to osteoporosis?

1) Pregnancy

2) Men with prostate cancer

3) Cola consumption
1) Pregnancy - NO!

2) Men with prostate canceer - YES!

3) Cola consumption -
• women - YES!
• men - NO!
What is arthrology?
The study of how bones are connected to each other
What are the 3 components of bone?
1. Bone

2. Cartilage: hyaline and/or fibrocartilage

3. Dense (aka fibrous) connective tissue
What are the two classifications of bone?
Degree of movement and structure
What are the 3 degrees of movement?
1. Synarthrosis - no movement

2. Amphiarthrosis - slightly movable

3. Diarthrosis - free movement
What is a general rule for band length and movement?
The longer the band the easier it moves
What are the 3 types of bone structure?
1. Fibrous

2. Cartilaginous

3. Synovial
Fibrous Structure
Bones fastened together by thin (parallel collagen fibers) layers of fibrous (i.e. dense straps or bands) connective tissue
What are the 3 types of fibrous structures?
1. Syndesmosis

2. Suture

3. Gomphosis
Syndesmosis
• joint consists of long fibrous band which forms interosseous ligament

• amphiarthrosis

• connects tibia and fibula
Suture
• only between some bones of the skull; short fibrous band forms sutural ligament

• synarthrosis
Gomphosis
• articulation between tooth root and bony socket; short fibrous band forms periodontal ligament

•synarthrosis

• cementum also helps hold tooth in place
Cartilaginous Structure
Connection consists of firbrocartilage and/or hyaline cartilage
What are the 2 types of cartilaginous structures?
Synchondrosis and symphysis
Synchondrosis
• Bones united by a band of hyaline cartilage

• synarthrosis

• e.g. epiphyseal plate (temporary sychondrosis)

• e.g. joint b/t first rib and sternum
Symphysis
• articular surfaces covered by hyaline cartilage (little bit), which in turn is attached to a pad of fibrocartilage (main component)

• amphiarthrosis

• e.g. pubic symphysis

• e.g. b/t 2 vertebral bodies
Synovial Structure
• Space between articulating bones filled with synovial fluid

• diarthrosis (freely movable)
What is the general structure of a synovial structure?
• articular ends of bone covered with thin layer of hyaline cartilage (e.g. the articular cartilage)

• Joint encased in joint capsule
What is the joint capsule of the synovial structure composed of?
• Fibrous joint capsule (capsular ligament) - thick, fibrous outer layer contiguous with periosteum of bones

• Synovial Membrane - thin inner layer covering all non-cartilaginous surfaces
1) What is the synovial fluid?

2) What is its function?
1) Secreted by synovial membrane, filling synovial cavity

2) Lubricant, pillow/cushion, nurishment for articular cartilage
What are the associated structures of the synovial structure?
1) Meniscus - firbrocartilage pad located between articular surfaces (shock absorber, makes tibia and fibula fit together to stabilize the joint)

2) Bursa - closed fluid-filled sac (pillow between bone surface and something moving over it

3) Other ligaments, in addition to the fibrous joint capsule