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45 Cards in this Set
- Front
- Back
What is the effect of an excess amount of Pituitary Growth Hormone (GH)?
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• children - leads to gigantism (the rate of growth increases and the time period increases)
• adults - acromegaly (increase in size of wrist, ankle, mandible, and nose) |
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What is the effect of a deficit in Pituitary Growth Hormone (GH)?
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• children - leads to dwarfism
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What are the 6 types of trauma and injury to bone (fracture)?
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1. Simple
2. Compound 3. Comminuted 4. Compression 5. Avulsion 6. Greenstick |
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Simple Fracture
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Bone broken but not displaced
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Compound Fracture
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Bone breaks through the skin
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Comminuted Fracture
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A complete break, but the bone is fragmented (many small pieces)
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Compression Fracture
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Bone collapses under compressive forces or telescopes into itself (common in the vertebrae)
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Avulsion Fracture
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Tendon or ligament pulls bone away at the site of attachment
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Greenstick
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• Incomplete fracture (not all the way through) and bending of the bone.
• the break and the bend are on opposite sides • Common in children |
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What are the 5 steps of the healing of a fracture?
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1. Fracture hematoma (blood clot) forms from the ruptured/severed blood vessels
2. A soft callus forms(mixture of spongy bone and fibrocartilage) 3. A hard callus forms by mineralization of soft callus (ossification) 4. Remodeling of hard callus to mature bone (i.e. compact and spongy) |
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Spongy bone is made by:
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Osteoblast
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Fibrocartilage is made by:
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Fibroblasts brought in by blood vessels
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After remodeling a bulge is present. What does this tell the body?
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That it is a weak area.
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Osteitis
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Inflammation of bone tissue caused by injury or infection
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What are the two types of Osteitis?
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Periostitis and Osteomyelitis
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What is the difference between Periostitis and Osteomyelitis?
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Periostitis: inflammation of periosteum caused by trauma or infection (exterior, scoring or pitting)
Osteomyelitis: Inflammation of bone interior caused by bacteria, usually initially entering the bone via wound or via bloodstream (interior, destruction of spongy bone from the inside out) |
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Tuberculosis
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Can spread to the spongy bone (particulary of the vertebral bodies), resulting in bone and joint destruction
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What are neoplasms?
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Tumors, out of control growth
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What are the four types of bone neoplasms and are they benign or malignant?
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Benign: Osteochondroma and Osteoma
Malignant: Osterogenic sarcoma (osteosarcoma), multiple myeloma |
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What is the difference between benign and malignant?
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Benign - not lethal
Malignant - lethal |
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What effect can aging have on bone?
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Osteoporosis
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What is osteoporosis?
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The reduction in bone mass due to deossification, most prevalent in middle aged and elderly women (post menopausal)
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When someone has osteoporosis what specifically happens to the bone?
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• Thinning of the trebecule (spongy bone)
• The osteoclasts break down boney connective tissue faster than the osteoblasts can build them |
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Why is osteoporosis prevalent in middle-aged and elderly women?
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• women have less bone mass than men
• women lose bone mass sooner (age 35) and faster than med do • by menopause women lose 25 - 35% bone, it doesn't happen to men until 60 or later |
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Which of the following 3 contribute to osteoporosis?
1) Pregnancy 2) Men with prostate cancer 3) Cola consumption |
1) Pregnancy - NO!
2) Men with prostate canceer - YES! 3) Cola consumption - • women - YES! • men - NO! |
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What is arthrology?
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The study of how bones are connected to each other
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What are the 3 components of bone?
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1. Bone
2. Cartilage: hyaline and/or fibrocartilage 3. Dense (aka fibrous) connective tissue |
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What are the two classifications of bone?
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Degree of movement and structure
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What are the 3 degrees of movement?
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1. Synarthrosis - no movement
2. Amphiarthrosis - slightly movable 3. Diarthrosis - free movement |
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What is a general rule for band length and movement?
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The longer the band the easier it moves
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What are the 3 types of bone structure?
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1. Fibrous
2. Cartilaginous 3. Synovial |
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Fibrous Structure
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Bones fastened together by thin (parallel collagen fibers) layers of fibrous (i.e. dense straps or bands) connective tissue
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What are the 3 types of fibrous structures?
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1. Syndesmosis
2. Suture 3. Gomphosis |
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Syndesmosis
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• joint consists of long fibrous band which forms interosseous ligament
• amphiarthrosis • connects tibia and fibula |
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Suture
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• only between some bones of the skull; short fibrous band forms sutural ligament
• synarthrosis |
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Gomphosis
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• articulation between tooth root and bony socket; short fibrous band forms periodontal ligament
•synarthrosis • cementum also helps hold tooth in place |
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Cartilaginous Structure
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Connection consists of firbrocartilage and/or hyaline cartilage
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What are the 2 types of cartilaginous structures?
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Synchondrosis and symphysis
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Synchondrosis
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• Bones united by a band of hyaline cartilage
• synarthrosis • e.g. epiphyseal plate (temporary sychondrosis) • e.g. joint b/t first rib and sternum |
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Symphysis
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• articular surfaces covered by hyaline cartilage (little bit), which in turn is attached to a pad of fibrocartilage (main component)
• amphiarthrosis • e.g. pubic symphysis • e.g. b/t 2 vertebral bodies |
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Synovial Structure
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• Space between articulating bones filled with synovial fluid
• diarthrosis (freely movable) |
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What is the general structure of a synovial structure?
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• articular ends of bone covered with thin layer of hyaline cartilage (e.g. the articular cartilage)
• Joint encased in joint capsule |
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What is the joint capsule of the synovial structure composed of?
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• Fibrous joint capsule (capsular ligament) - thick, fibrous outer layer contiguous with periosteum of bones
• Synovial Membrane - thin inner layer covering all non-cartilaginous surfaces |
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1) What is the synovial fluid?
2) What is its function? |
1) Secreted by synovial membrane, filling synovial cavity
2) Lubricant, pillow/cushion, nurishment for articular cartilage |
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What are the associated structures of the synovial structure?
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1) Meniscus - firbrocartilage pad located between articular surfaces (shock absorber, makes tibia and fibula fit together to stabilize the joint)
2) Bursa - closed fluid-filled sac (pillow between bone surface and something moving over it 3) Other ligaments, in addition to the fibrous joint capsule |