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8 Cards in this Set
- Front
- Back
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Open Neural Tube defects (NTDs)
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MMC: Myelomeningocele (involves CNS tissues)
Meningocele (involves maters, not CNS tissue) |
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Closed NTDs (neural tube defects)
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Lipomyelomeningocele
Split cord malfunction |
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Open Myelomeningocele
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Donut shaped ring formed by stack verterbra. In OTC, have normal body, but no lamina or spinous processes. Normal spinal cord but flattened, so cord goes out back.
Neural tube (endoderm) doesn't close in itself. Non closed portion can be outside of body. 1/2000 or so births. Incidence reduced by 50% (folic acid supplements). Also early detection and possible termination. |
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Associated anomalies of NTDs.
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Hydrocephalus
Type 2 Chiari malformation Brainstem anomalies (medullary kink, downward displacement of medulla) Urinary and bowel incontinence Lower extremities paralysis/deformities (like club feet) |
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Hydrocephalus
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Buildup of spinal liquid in brain. Can use shunt to drain.
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Type 2 Chiari
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Herniation of brain (cerebellum)
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Location of Neuro deficit versus need for shunt
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Higher up deformity = less function = more morbidity/mortality/need for care.
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Fixing NTDs
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Neurosurgery/urology/orthopedics
Repair within 72 hours of birth. Prevents infection, one of main killers. Can fix intrauterine!! |
