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17 Cards in this Set
- Front
- Back
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Types of Sphingolipids
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sphingomyelin
cerebrosides sulfatides globosides gangliosides |
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Precursors for sphingosine
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Serine
Palmitoyl CoA |
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How is Ceramide formed?
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R: Sphingosine + Acyl CoA
P: Ceramide + COASH |
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How is sphingomyelin formed
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R: Ceramide + CDP-Choline
P: Sphingomyelin + CMP R: Ceramide + Phosphatidyl Choline P: Sphingomyelin + DAG |
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four types of glycosphingolipids
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Cerebrosides
Sulfatides Globosides Ganglioside |
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PAPS, what is it used for
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3'phospoadenosine-5'phosphosulfate
used in combination with galactocerebroside to yield sulfatide + PAP |
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Gaucher Disease
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deficiency in Glucocerebrosidase
people can't synthesize ceremide |
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Tay-Sachs Disease
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hexoaminidase A deficiency
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what is the most abundant protein in the human body,
function, how much in typical body |
Collagen
Maintain shape and resist deformation ~13lb in 150lb person |
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general AA composition characteristic in COLLAGEN
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33% glycine (IMPORTANT)
10% praline 10% hydroxylproline 1% hydroxlysine |
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4 modification that takes place in procollagen
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Hydroxylation (requires Vit. C)
Glycosylation N-linked glycosylation formation of di-sulfide bonds formation of triple helix |
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what is elastin,
Color Function |
yellow insoluble protein
2nd major protein in conn. tiss. elastic structure in blood vessels |
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what enzyme modifies lysine to form, which will eventually cause cross-linking to occur in collagen and in elastin?
What are the structures in elastin crosslinks called? |
a. Lysyl Oxidase
b. Desmosine |
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difference between proteoglycan and collagen/elastin
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Core Protein and glycosaminoglycan
polysaccharides content very high |
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what does striated mean
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enclosed by a membrane known as the sarcolemma that can be excited by an electrical impulses from nerves
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what is the composition of the think filaments in the sarcomeres
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A band, composed of protein myosin
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what is the composition of the thin filaments in the sarcomeres
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lie in I-band and extend to A-band
Composed of: proteins, actin, tropomyosin, troponin |
