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282 Cards in this Set
- Front
- Back
The __________is the largest lobe, making up _____ of the cortex.
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Frontal lobe, 1/3 of the cortex,
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The frontal lobe is the _________-most portion of the cortex, also known as the _________lobe.
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anterior-most portion of cortex, thinking lobe.
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Frontal lobe contains __________ area, an important area for speech motor planning.
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Broca's area
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Broca's area is responsible for _________ language production.
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expressive language production
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The _______ _______ in the frontal lobe is the site of initiaton of voluntary motor movement (motor output)
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motor strip
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Motor function is ______ arrayed along the motor strip.
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spatially arrayed
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The ___lobe is the primary site body(_________) for sensory reception
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Parietal lobe, somatic (body) sense reception.
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All senses that reach ________, terminate in the parietal lobe.
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consciousness
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The ______________, is the site of somatic sensation from various body regions
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postcentral gyrus
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______ ______ is spatially arrayed along the postcentral gyrus.
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Sensory function
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Mr. Jones had a stroke. You showed him a picture of a hat. He has mild aphasia, saying, " I know what that is, but I can't say the word - I know you put it on your head".
What area of the brain has been affected? |
Damage to Broca's area - problem with language retrieval
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The _______ lobe is the site of auditory reception
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temporal lobe
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The Temporal lobe contains __________ _________, an important area for receptive language processing.
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Wernicke's area
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Wernicke's Area, located in the ________lobe is responsible for ____________ ____________ ________.
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temporal lobe, receptive language processing, language decoding
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The temporal lobe is the prominant ________ lobe, separated from the ___________ lobe and _______ lobe by the ________ fissure.
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temporal lobe, prominant lateral lobe, separated from the parietal and frontal lobes by the lateral fissure.
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The _______ lobe, the most posterior lobe, is responsible for receiveing ______ stimulation.
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Occipital lobe, most posterior lobe, responsible for receiving visual stimulation.
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Occipital Lobe is the site responsible for receiving:
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Visual input to the cerebrum.
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Insular lobe is revealed by________ ___ ______, where it lies deep in the _________ __________.
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Deflecting the Temporal lobe (underneath temporal lobe), lies deep in the lateral sulcus.
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Limbic Lobe is located where?
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Limbic Lobe - not a distinct region
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The Limbic Lobe arises from functional relationships associated with:
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emotional behavior, motivation, sex drive, affect
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Medial surface of the Cerebral Cortex is known as the __________.
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Corpus Collosum
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The Corpus Collosum is responsible for what?
Is it typically larger in men or women? |
Providing communication between the two hemispheres.
Larger in women. |
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The hippocampus, a structure involved in ________, is located on the ________surface of the ______ _______.
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Memory,
Inferior surface of the Cerebral Cortex |
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Myelinated Fibers
a) made up of neuron bodies |
grey matter
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Myelinated Fibers
b) made up of myelinated axon fibers - form the communication link among the ___________ |
b) white matter
communication link among the neurons |
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Myelinated Fibers - White Matter
___ types of fibers - connect the _______of the cerebral cortex |
3 types of fibers
Connect the regions of the cerebral cortex |
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Myelinated Fibers - White Matter
projection fibers - |
connect the cortex with distant locations
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Myelinated Fibers - White Matter
association fibers- |
Connect regions of the same hemisphere
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Myelinated Fibers - White Matter
commissural fibers |
connect corresponding regions of the two hemispheres
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Myelinated Fibers - White Matter
The Corpus Callosum is the major group of _____ _______ |
Commissural Fibers
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Anatomy of the Subcortex
A collection of cell bodies involved in control of movement. |
basal ganglia
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Anatomy of the Subcortex
Basal Ganglia (Basal Nuclei) structures include the: 1,2.3 |
1. Caudate Nucleus
2. Putamen 3. Globus Pallidus |
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Anatomy of the Subcortex
Hippocampal Formation Located? Function? |
Located in the temporal lobe.
Function: memory |
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Anatomy of the Subcortex
The paired _______ are the final relay for _______ information directed toward the cerebral cortex. |
paired thalami
sensory information |
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Anatomy of the Subcortex
All sensation with the exception of _____, passes through the thalamus. |
olfaction (smell)
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Anatomy of the Subcortex
Interacts with the globus pallidus to control movement. |
Subthalamus
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Anatomy of the Subcortex
Hypothalamus |
controls bodily functions and desires
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Reproductive behavior, physiology, desire for food and water, perception of satiation, control of digestive processes, and metabolic functions are controlled by?
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Hypothalamus
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Anatomy of the Subcortex
Responsible for metabolic functions including maintenance of water balance & body temperature. |
Hypothalamus
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Cerebrovascular System
*Although the brain makes up only __% of the body weight, it consumes ___% of the oxygen transported by the vascular system to meet the metabolic requirements of nervous tissue. |
2% of body weight
Consumes 20% of oxygen |
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Cerebrovascular System
Anterior cerebral arteries |
Serve the medial surface of the brain
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Cerebrovascular System
Middle Cerebral artery |
serves the alteral cortex includeing temporal lobe, motor strip, Wernicke's area and much of the parietal lobe.
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Cerebrovascular System
The most common site of occlusion, which may result in significant speech & language deficits if the occlusion ivolves the dominant cerebral hemisphere. |
Middle Cerebral Artery
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Cerebrovascular System
Most people have dominant _____hemisphere, meaning that speech and language are controlled there. |
Left hemispere
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Cerebrovascular System
_________ arteries - branch to form the ____ & _____ spinal arteries with ________components serving the _____brainstem. |
Vertebral arteries -
anterior & posterior ascending components serving ventral brainstem |
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Cerebrovascular System
Circle of Willis |
a series of communicating arteries that provides redundant pathways for bloodflow to regions of cerebral cortex, equalizing pressure.
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Cerebrovascular System
Venous drainage |
The blood supply for the brain that requires a return route for blood that has circulated and exchanged its nutrients.
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Cerebrovascular System
A system of blood vessels (veins) which provide the means for carbon-dioxide rich blood to the lungs for reoxygenation. |
Veinous Drainage
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Cerebrovascular System
Venus drainage is accomplished by means of a series of _______ & deep ________ (sinuses). |
superficial & deep cisterns
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Blood returns to the general bloodstream by means of the ______veins.
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Jugular veins
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Cerebrovascular System
Spinal cord drainage is accomplished by means of ________ veins. |
Radicular veins
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Cerebrovascular System
Obstruction |
Critical blockage of the blood supply, caused when a foreign body within the blood vessel (thrombus) creates a blockageto blood flow (thrombosis) or becomes an embolus when released into bloodstream..
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Cerebrovascular System
Aneurysm |
a ballooning of a blood vessel, rupture of which results in blood being released into that region of the brain.
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Cerebellum
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Largest component of the hindbrain
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Cerebellum - responsible for:
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Coordinating motor commands with sensory inputs, communicating with brain stem, cerebrum and spinal cord.
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Cerebellum is divided into___lobes, and helps with sense of _____, space in equilibrium
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3 lobes
helps with sense of balance |
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Cerebellum
1. flocculondular lobe |
coordinates position in space via vestibular nuclei
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Cerebellum
2. anterior lobe |
coordinates postural adjustment against gravity.
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Cerebellum
3. posterior lobe |
mediates fine motor adjustments
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Cerebellum
The cerebellum communicates with the rest of the nervous system via the: |
superior, middle and inferior cerebral peduncles
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Cerebellum
The cerebellar cortex consists of ___ layers - name them. |
3 layers
outer molecular layer, Purkinje layer, deep granular layer |
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Cerebellum
The 4 types of cells that are responsible for coordinating input received from the nervous system |
Golgi, basket, stellate and Purkinje cells
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Cerebellum
Four pairs of nuclei are found in the cerebellum |
1. dentate nucleus
2. emboliform nucleus 3. globose nucleus 4. fastigal nucleus |
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Cerebellum
The dorsal spinocerebellar tract and the cuneocerebellar tract communicate _________ from the upper body to the cerebellum. |
procioception (sense of body - muscle soreness), temperature, and touch sense
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Cerebellum
The ventral spinocerebellar and rostral spinocerebellar tracts mediate: |
ipsilateral (same side sensory reception) proprioceptive information and pain sense from the lower and upper body
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Cerebellum
The olivocerebellar tract mediates information received from the: Big Dog |
spinal cord, cerebral cortex and other structures and provides communication between cerebellar hemispheres.
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Anatomy of the Brainstem
The brainstem consists of the |
medulla oblongata, pons and midbrain
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Anatomy of the Brainstem
Evolutionarily order the cerebral cortex, brainstem and spinal cord. |
spinal cord, the most primitive part of CNS
brainstem - middle Cerebral cortex - most evolved |
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Anatomy of the Brainstem
The brainstem reflects an intermediate stage of organization, between the: |
simple reflexive responses seen at the level of the spinal cord and the complex responses generated by the cerebral cortex.
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Anatomy of the Brainstem
Cranial nerves and their nuclei arise from the _____ and basic bodily functions for life are ________ _____. |
brainstem, basic bodily functions for life maintained there
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Superficial Brainstem Landmarks:
_________The inferior-most segment of the brainstem, sits anterior to spinal cord. Damage to this area is imminently life-threatening. |
Medulla Oblongata (Medulla)
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Superficial Brainstem Landmarks:
pyramidal decussation |
the point within the edulla at which fibers of the corticospinal tract cross from one side to the other
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Superficial Brainstem Landmarks:
Most of the axons carrying motor commands from the ____ hemisphere cross to the ___ side of the medulla to continue down through the spinal cord on the _____side. |
left, cross to the right,
right side of spinal cord |
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Superficial Brainstem Landmarks:
At the _____ ____ the fibers divide into lateral and anterior _____ tracts. |
pyramidal decussation,
lateral and anterior corticospinal tracts. |
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Superficial Brainstem Landmarks:
Corticospinal tracts in the pyramidal decussation are responsible for: |
activation fo skeletal muscles of the extremeties.
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Superficial Brainstem Landmarks:
Commands to move the skeletal muscles of the extremities are controlled by the: |
Cerebrum
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Superficial Brainstem Landmarks:
Pons- Located: Function: |
Located above the medulla.
Serves as bridge between medulla and midbrain. |
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Superficial Brainstem Landmarks:
The site of 4 cranial nerve nuclei and origin of middle and superior cerebellar peduncles. |
Pons
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Superficial Brainstem Landmarks:
Middle and superior cerebellar peduncles Location: Function |
in Pons
serve as super-highways for communication with cerebellum |
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Superficial Brainstem Landmarks:
Midbrain |
superior most structure of brainstem
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Superficial Brainstem Landmarks:
Which part of the brainstem gives rise to the III & IV cranial nerves & contains the cerebral peduncles leading to & from cerebrum? |
Midbrain
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Superficial Brainstem Landmarks:
Bottom to Top |
1 .Spinal Cord
2. Medulla 3. Pons 4. Midbrain |
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Deep Structures of the Brainstem
The brainstem can not be visualized from above because, like the spinal cord, it is organized ______. |
organized vertically
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Deep Structures of the Brainstem
The brainstem is made up ofcolumnar nuclei and tracts that: |
serve the periphery spinal cord, cerebral, cerebellar and subcortical structures. (anatomically up and down rather than horizontal)
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Deep Structures of the Brainstem
Reticular formation |
important mass of nuclei that spans the medulla, pons and midbrain
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Deep Structures of the Brainstem A composite of brainstem nuclei, forming the oldest part of the brainstem and representing our first evolutionary effort at complex processing.
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Reticular Formation
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Deep Structures of the Brainstem
Reticular Formation- an important mass of nuclei, beginning _____the level of the decussation of the pyramids and making up the _______structure of the _________. |
begins above the decussation of pyramids, making up central structure of brainstem.
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Deep Structures of the Brainstem
The Reticular Formation is _______ important for _____function, as it contains nuclei associated with ____& maintenance of _____. |
extraordinarily important for life function
contains nuclei associated with respiration and maintenance of blood pressure |
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Cranial Nerve Classification
Cranial nerves are referred to by ___ , ___ or _____. There are _____ cranial nerves |
referred to by name, number or both
12 |
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Cranial Nerve Classification
______ are used to label cranial nerrves and the number represents: |
Roman numerals
Inverse height in the brainstem |
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Cranial Nerve Classification
Midbrain - Cranial Nerves # _ - _ |
I-IV
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Cranial Nerve Classification
Pons - Cranial Nerves # _ - _ |
V - VIII
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Cranial Nerve Classification
Medulla - Cranial Nerves # _ - _ |
IX through XII
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Cranial Nerve Classification
Unlike _____ nerves, cranial nerves are differentiated based up on __ defining categories. |
Unlike spinal nerves,
cranial nerves - differentiated based on 7 defining categories |
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Cranial Nerve Classification
Functional divisions for classification of Cranial Nerves |
General / Special
Somatic /Visceral area of service Nerves- Efferent / Afferent/ Both |
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Cranial Nerve Classification
GSA - General Somatic Afferent Nerves - |
sensory nerves involved in communicating the sensory info . from skin, muscles and joints, including pain and temperature
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Cranial Nerve Classification
SSA - Special Somatic Afferent Nerves |
serve special body senses such as vision and hearing
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Cranial Nerve Classification
GVA - General Visceral Afferent Nerves |
transmit sensory informaiton from receptors in visceral structures such as the digestive tract
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Cranial Nerve Classification
SVA - Special Visceral Afferent Nerves |
provide information from the special visceral senses of taste and smell
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Cranial Nerve Classification
GVE- General Visceral Efferent Nerves |
autonomic fibers serving viscera and glands
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Cranial Nerve Classification
GSE- General Somatic Efferent Nerves |
Provide innervations of skeletal muscle and are important for speech production.
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Cranial Nerve Classification
SVE - Special Visceral Efferent Nerves |
involved with innervation of the larynx, pharynx, soft palate, face, and muscles of mastication
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Specific Cranial Nerves
I |
Olfactory - sense of smell
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Specific Cranial Nerves
II |
Optic - communicates visual information to the brain
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Specific Cranial Nerves
III |
Oculomotor -
provide innerations for eyes |
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Specific Cranial Nerves
IV |
Trochlear - provide innervations for eye movements
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Specific Cranial Nerves
V |
Trigeminal- innervates muscles of mastication and the tensor veli palatini & communicates sensation from the face, mouth, teeth, mucosal lining and tongue.
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Specific Cranial Nerves
VI |
Abducens - provide innervations for eye movements
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Specific Cranial Nerves
VII |
Facial - innervates muscles of facial expression and the sensory component serves taste of the anterior two-thirds of tongue
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Specific Cranial Nerves
VIII |
Vestibulocochlear - mediates auditory and vestibular sensation
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Specific Cranial Nerves
IX |
Glossopharyngeal - serves the posterior tongue taste receptors as well as somatic sense from the tongue, fauces, pharynx, and Eustachian tube. The stylopharyngeus and superior pharyngeal constrictor muscles receive motor innervations via this nerve.
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Specific Cranial Nerves
X |
Vagus- somatic sensation of pain, touch and temperature fromt eh region of the ear drum, pain sense from the pharynx, larynx, esophagus, and other regions; motor innervation for the intrinsic muscles of the larynx
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Specific Cranial Nerves
XI |
Accessory - Innervates the sternocleidomastoid and trapezius muscles, and collaborates with the Vagus nerve in activation of palatal, laryngeal and pharyngeal muscles.
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Specific Cranial Nerves
XII |
Hypoglossal - innervates the muscles of the tongue with the exception of the palatoglossus
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Anatomy of the Spinal Cord
The spinal cord is/is not the same as the vertebral column. Spinal cord is made up of : Vertebral column made up of : |
is not same as vertebral column
Long mass of neurons Bone |
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Anatomy of the Spinal Cord
The spinal cord is the: |
the information lifeline to and from the periphery of the body.
the link between the brain and body |
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Anatomy of the Spinal Cord
The spinal cord is composed of: |
aggregation fo many single nerve fibers formed into bundles of fibers (called tracts) with functional unity.
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Anatomy of the Spinal Cord
The tracts (bundles of fibers) in the spinal cord provide _______ between the ___ & ___, and each bundle has ______properties. |
provide communication between the brain and body
bundles have unique properties |
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Anatomy of the Spinal Cord
The spinal cord can be viewed: |
in it's length (vertical anatomy) and in cross-section (transverse anatomy) -like rings on a tree
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Vertical Anatomy of Spinal Cord
The spinal cord is a ____ ____ of ____, consisting of _______. |
longitudinal mass of columns,
consisting of neurons |
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Vertical Anatomy of Spinal Cord
Gray portions of the spinal cord are: |
cell bodies within the spinal cord
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Vertical Anatomy of Spinal Cord
White portions of spinal cord are: |
myelinated fibers of tracts that communicate information to and from the brain
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Vertical Anatomy of Spinal Cord
Spinal cord begins at the ___, and courses about ___cm through the ____ ____, of the vertebral column. The spinal cord is present down tho the level of the ____ ____ vertebrae. |
begins at the foramen magnum of skull
courses 46 cm through vertebral canal of vertebral column to 1st lumbar vertebrae |
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Vertical Anatomy of Spinal Cord
Spinal cord is wrapped in ___ ___. Attached to vertebral column laterally by __ __& firmly attached to coccyx by _____ _______. |
wrapped in meningeal linings, attached laterally to vertebral column by denticulate ligaments coccygeal ligament.
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Vertical Anatomy of Spinal Cord
____ pairs of spinal nerves (# unpaired) arise at ______ intervals on spinal cord |
31 pairs
regular intervals |
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Vertical Anatomy of Spinal Cord
Spinal nerves are referred to in same manner as: |
vertebrae
Cervical, C_ ThoracicT_, Lumbar, L_ Sacral S_, Coccygeal |
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Vertical Anatomy of Spinal Cord
There are _ pairs of cervical spinal nerves, __ pairs of thoracic nerves, _ pairs of lumbar nerves, _ pairs of saccral nerves, _ pairs of coccygeal nerves |
8 pair Cervical Spinal NervesC1 - C8
12 pair Thoracic Nerves - T1-T12 5 pair - Lumbar L1-L5 5 pair - Saccral - S1-S5 1 pair Coccygeal nerves |
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Vertical Anatomy of Spinal Cord
During embryonic development, the spinal cord is __ ___ ____, but as braind and body develop, the spinal cord moves ___ in the canal, so adult spinal nerves course ____ before exiting __ ___ |
the same length as VC
up in canal adult course down before exiting vertebral column |
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Vertical Anatomy of Spinal Cord
Spinal nerves have both sensory ___and motor ___components. Sensory function is generally related to___ ___- upper nerves serve ____ ___& so forth, |
sensory - afferent
motor - efferent segment level - upper nerves serve upper body, etc.. |
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Vertical Anatomy of Spinal Cord
plexus |
network of nerves that physically communicate with other nerves
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Transverse Anatomy
The simplest stimulus-response system of the nervous system - the most basic means the nervous system has of responding to its environment |
Reflex Arc
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Transverse Anatomy
Reflex arc works by: |
permitting rapid movements without participation of higher neural systems
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Transverse Anatomy
Because reflexes are executed at level of the spinal cord, they permit: very ____ but _____responses to stimuli - consequently most reflexes serve ____ functions (examples) |
very fast, but indiscriminate responses,
protective function blink, cough, sneeze, etc... |
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Transverse Anatomy
Upper Motor Neurons (UMN's) |
part of the CNS - efferent (motor) fibers descending from upper brain levels (axons pass through midbrain, brain stem, spinal cord to synapse with cell bodies of lower motor neurons)
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Transverse Anatomy
Upper Motor Neurons (UMN's) bring commands from upper brain levels that: |
activate or inhibit muscle function by synapsing with LMN's (lower motor neurons).
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Transverse Anatomy
Lower Motor Neurons (LMN's) |
consist of dendrites and soma within the spinal cord as well as axon components that communicate with muscle fiber; part of PNS.
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Transverse Anatomy
Specialized junctions where Lower Motor Neurons communicate with muscle fibers: |
Motor Endplates
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Pathways of the Spinal Cord
Neurons are referred to as ___-order, ___-order, etc.. to indicate: |
first-order, second-order, etc.. to indicate their number in the chain
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Pathways of the Spinal Cord
The afferent neuron in a chain will be the _____ neuron, and the next neuron following synapse will be the ______., up to the ____ point in neural chain. |
first-order neuron,
second-order neuron terminal point |
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Pathways of the Spinal Cord
Efferent tracts, such as the corticospinal tract, transmit information: |
Efferent transmit from brain down to spinal nerves
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Pathways of the Spinal Cord
Afferent tracts, such as the spinothalamic tract, transmit information concerning_____ to ______. |
Afferent tracts - information concerning physical state of lower limbs up to higher brain centers.
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Pathways of the Spinal Cord
The corticospinal tract runs from the: ___ to ___ and innervates _____ ____ |
runs from the cortex to the spine and innervates skeletal muscle
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Pathways of the Spinal Cord
The corticobulbular tract,although not a tract of the ____ cord is very important for speech - innervates many muscles of the ____, ___, ____, and ___, and serves ___ ___ nerves for speech. |
not tract of spinal cord,
innervates muscles of face, neck, pharynx, and larynx - serves motor cranial nerves for speech |
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Neuron Function
synapse - |
union of open space between two neurons where communication occurs between axon of one neuron and dendrite of another
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Neuron Function
synaptic cleft |
tiny space between an axon and dendrite
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Neuron Function
Transmission of nerve impulses across synaptic cleft is a ____process involving: |
chemical process involving
ion exchange, sodium and potassium. |
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Neuron Function
Briefly explain Transmission of nerve impulses: |
Neurotransmitter substance is released by axon and drifts across synaptic cleft where it excites the dendrite of a second neuron. The dendrite's excitationcauses change in its electric charge, causing the second neruon to fire, sending signal down its axon to excite dendrites of another neuron.
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Neuron Function
Neurotransmitters can cause either : |
excitation or inhibition of neurons.
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Neuron Function
Occurs when a single neuron takes input from thousands of other neurons to produce a single response. Mass of information is distilled into a single response. |
convergence
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Neuron Function
Occurs when a single neuron makes synapse with thousands of other neurons: single piece of information transmitted to many other neurons |
Divergence
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Neuron Function
Myelinated fibers conduct nerual impulses more rapidly than demylelinated fibers primarily because of: |
salutatory conduction - jumping
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Muscle Function
point where nerve and muscle communicate |
neuromuscular junction -
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Muscle Function
The basic unit of skeletal muscle control, consisting of the motor neuron, its axon and the muscle fibers it innervates |
motor unit
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Muscle Function
Two basic types of fibers - description |
1. slow twitch fibers - longer response time, remain contracted 5 times longer, involved in maintenance of posture
2. fast twitch fibers - shorter, faster movement, involved in fine & rapid motor function - tongue-tip movement |
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Muscle Function
Muscle spindles provide feedback to the neuromotor system about muscle length, tension, motion and position. |
muscle length, tension, motion and position.
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Higher Functioning
lively debate concerning ____ __ ____ has been going on for well over 100 years. Briefly describe localizationists, equipotentiality, regional equipotentiality. |
localization of function within the brain,
localization - speech cont. happens only in specific local areas equipotentiality - any function can be controlled by any area of brain regional equipotentiality - regions of control |
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Regions of brain functioning
Regions of primary activity |
primary sensory and motor regions including primary reception are for somatic sense, primary motor area, primary auditory cortex, primary region of visual reception.
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Regions of brain functioning
Higher area orders of processing - |
responsible for extracting features of the stimulus - located adjacent to primary regions
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Regions of brain functioning
Association Areas |
regions of highest cognitive processing where sensory information is integrated with memory
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Regions of brain functioning
Briefly describe how sensory information moves through the regions: |
Information is received from our senses at primary reception areas and we extract it and put it together with other information associated with the modality at higher-order areas of processing. This information is passed to association areas for the highest level of cognitive processing.
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Motor System Lesions
Damage to specific regions of the brain was used to infer: |
the area of the brain responsible for various functions of the brain.
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Motor System Lesions:
Dysarthria - ____ disorder characterized by: Caused by damage to : Resulting in damage to: |
speech disorder - characterized by muscular weakness & reduction of motor control
motor strip - Resulting in muscular weakness, lack of motor function on side of body opposite lesion. |
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Motor System Lesions:
Flaccid Dysarthria |
characterized by flaccid paralysis - manifested as muscular weakness and hypotonia (lack of muscle tone)- caused by damage to Lower motor neurons- generally reflects damage to cranial nerves serving speech muscles
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Motor System Lesions:
Spastic Dysarthria |
characterized by spastic paralysis banifested as hyperrefleia - hair trigger reflexes - and hypertonia (too much muscle tone) caused by damage to upper motor neurons.
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Motor System Lesions:
Ataxic Dysarthria - |
characterized by loss of coordination, deficits in achieving an articulatory target and problems in coordinating rate, range and force of movement, caused by damage to cerebellum or brainstem vestibular nuclei or both.
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Motor System Lesions:
Hyperkinetic Dysarthria - |
characterized by extraneous involuntary movement of speech musculature in addition to movement produced voluntarily; articulators move with out voluntary muscular contraction and this is overlaid on the speech act; caused by damage to the extrapyramidal system.
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Motor System Lesions:
Hypokinetic Dysarthria - |
Characterized by paucity of movement (lack of movement) most often caused by Parkinson's disease - caused by damage to cells responsible for the production of dopamine, shortage of dopamine results in inhibited initiation of motor function, reduction of range of movement, rigidity, hand tremor
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Motor System Lesions:
Mixed Dysarthrias |
result from damage to more than one of the controlling systems
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Motor System Lesions:
Apraxia |
speech deficit of motor planning existing with no muscular weakness or paralysis. Caused by damage to parietal lobe and Broca's area.
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Aphasia
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language disorder
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Motor System Lesions:
Apraxia - |
like limb apraxia - can occur anywhere in body - limb has jerky movement
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Hemispheric Specialization
Left Cerebral Hemisphere governs: |
language, speech, detailed information and sequential processing, reading book, left to right, logic - 98% population
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Hemispheric Specialization
Right cerebral hemisphere governs |
Spatial, tonal information and holistic processing (viewing picture)
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Hemispheric Specialization
Lesions to Wernicke's Area in the dominant hemisphere: |
result in receptive language deficit with relatively intact language fluency - aphasia - language comprehension problem - talks fine, can't understand
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Hemispheric Specialization
Lesions to Broca's area in the dominant hemisphere: |
result in expressive language deficit - apraxia, trouble talking, expressing self, comprehension fine.
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Hemispheric Specialization
Lesions to Arcuate Fasciculus - connecting Broca & Wernicke's areas: |
results in conduction aphasia - characterized by inablity to repeat utterances heard adn by phoneme substitutions (literal paraphasias)
*Say what I say..".the dog is chasing the cat" , they say " the dog ate the bat" |
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Hemispheric Specialization
Lesions to Broca's area, Wernicke's area & arcuate fasciculus |
results in global deficits - comprehension, expression, repetition
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Hemispheric Specialization
Lesions to right hemisphere: |
often results in deficits in pragmatics (socially appropriate) misinformation of information carried in speech intonation, loss of communication nuance.(very literal)
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Hemispheric Specialization:
Lesions to frontal lobe |
often result in impaired judgement and failure to inhibit responses
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Hemispheric Specialization
Lesions to Hippocampus |
results in deficits in short term memory
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Right Hemisphere characterized by:
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holistic perception - whole picture
higher math, geometry, calculus, person's face, governs certain aspects of music, melody - visio-spatial intelligence - sense of direction |
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Left Hemisphere characterized by:
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sequential perception, left to right, reading a page, governs lower math skills, some aspects of music, in most people 98% governs Speech & Language, speech - motor act
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In 100% of right handed people speech and language are governed by
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the left hemisphere
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In 60% of left handed people speech and language are governed by,
1 1/2 -2% population S&L governed by: remaining multi-lingual fractional percentage may control S&L in : |
the left hemisphere
right hemisphere both hemispheres |
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Children with damaged hemisphere of brain that must be removed can usually compensate by -
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some functions of S&H being taken over by right hemisphere - but not perfect functioning.
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Mediates themral sense, cheek
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V Trigeminal
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Mediates sense of smell
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I Olfactory
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Mediates sense of pain for teeth
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V Trigeminal
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Innervates genioglossus & geniohyoid as well as transverse, vertical, inferior longitudinal and superior longitudinal lingual muscles
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XII Hypoglosal
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Innervates masseter, temporalis, tensor veli palatini, tensor tympani, medial and lateral pterygoid muscles
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V Trigeminal
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Innervates superior constrictor muscles
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IX Glossopharyngeal
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Mediates taste, anterior 2/3 of tongue
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VII facial
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Mediates taste in posterior 1/3 of tongue
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IX Glossopharyngeal
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Mediates sense of hearing
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VIII Vestibulocochlear
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Approximately how many neurons are in the humand body
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100,000,000,000
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The structure that is responsible for coordination
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Cerebellum
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A funcitonal dichotomy of the nervous system would include the subcategories of
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somatic and autonomic nervous systems
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A structural dichotomy of the nervous system would include the subcategories of
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central and peripheral nervous systems
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Involuntary visceral functions are governed by the
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autonomic nervous system
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Protective reactive responses such as goosebumps, sweating and pupil dilation are triggered by
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sympathetic nervous ssytem
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The type of cell that provides nutrients as well as a filter function is the
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glia
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The type of cell that is the functional building block o the nervous system is the
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neuron
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The typical site for reception of excitatory stimulation on a neuron is the
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dendrite
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Wich substance provides insulation for the axon, as well as a means of increasing rate of conduction of neural impulses?
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Myelin
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Also referred to as prosencephalon
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forebrain
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Also referred to as mesencephalon
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midbrain
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Also referred to as Rhombencephalon
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Hindbrain
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Landmarks of Cerebrum
# of Cerebral Hemispheres |
2
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Landmarks of Cerebrum
Separates L&R hemispheres. Within this landmark reside anterior ____ artery and its collatorals. |
Cerebral Longitudinal Fissure
w/in fissure - anterior cerebral artery |
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Landmarks of Cerebrum
Surface of brain is ____, because early in development as brain ____ outstrips ____, the cerebral cortex ____ on itself. Result is greater ___, more neural horsepower. |
convoluted, brain grown outstrips skull growth, brain doubles on itself, greater surface area, more neural horsepower.
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Landmarks of Cerebrum
The convolutions (mountains) |
Gyri (sing. Gyrus)
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Landmarks of Cerebrum
_____, (_____) involding valleys, separate convolutions |
Sulci (Sing. Sulcus)
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Landmarks of Cerebrum
Deeper grooves, valleys |
Fissure
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Landmarks of Cerebrum
Number of Cerebral Lobes, Name them: |
6 Cerebral Lobes
Frontal, Parietal, Occipital, Tempural, Insular, Limbic |
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Landmarks of Cerebrum
_____ _____, (_____ _____) divides temporal love from frontal and anterior parietal lobes |
Sylvian Fissure (Lateral Sulcus)
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Landmarks of Cerebrum
_____ ______ (___ ___) separates frontal & parietal lobes entirely. |
Rolandic fissure - (central sulcus)
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Cerebrum Layers
Outer surface (bark), between _ &_mm thick, consists of __ cell layers. |
Cerebral Cortex
2-4mm thick, 6 cell layers |
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Cerebrum Layers
Layers consist of 2 main cell types: 1. ___ large pyramid-shaped cells involved in motor function 2. smaller, star shaped, sensory & intercommunication cells |
Pyramidial
Non-pyramidial |
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Cerebrum Layers
Layers varying __ based on function ___ connect local regions ___ cells connect distal region. |
varying densities based on function
Non-pyramidial cells - connect local regions Pyramidial cells |
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Circulation of CSF
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CSF - 125 mL, replenished every 7 hours, constant pressure changes with body position, life-threatening condition if pathway is blocked, circulation of CSF begins in R&L lateral ventricle then subarachnoid space, then around brain & spinal cord, then eventually absorbed by veinous system
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Spinal Meningial Linings
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protect the spinal cord from movement/trauma
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CSF is bathed in ___ which provides;
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cerebrospinal fluid (CSF) provides cushion, nutrients, & waste removal
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Spaces in brain where CSF flows
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Ventricles
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System of ventricles consists of ___ cavities. List:
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System of Ventricles - 4 cavities
1. Right lateral ventricle 2. Left Lateral Ventricle 3. 3rd Ventricle 4. 4th Ventricle |
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Within each ventricle is a ___ ___ an aggregate of tissue, which produces ___. Plexus of ____ produces most ___.
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Choroid Plexus, produces CSF
Plexuses of Lateral Ventricles produces most CSF. |
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Menengial Linings
1. Dura Mater - Epidural space |
most superficial meningial lining, bi-layered , tough lining
---- Space between 2 layers |
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Menengial Linings
2. Arachnoid mater - |
spider-like structure which CSF flows through
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Menengial Linings
3. Pia Mater |
Thin membraneous covers contours of brain, contains arteries, & blood vessesls
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Anatomy of Cerebrum
Menengial Linings, __ layers 1 -3 list |
support brain, maintain in fluid suspension, 3 layers
1. dura mater 2. arachnoid mater 3. pia mater |
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Anatomy of Cerebrum
Dura Mater |
for brain protection takes on 4 major infoldings providing some isolation.
Divides brain sagitally and transversely |
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Anatomy of Cerebrum
Cerebrum |
(brain) most hightly evolved & organized structure of human body.
- largest structure of nervous system 3lbs. - billions of neurons - 2 hemispheres - left & right -wrapped by 3 menengial linings to protect & support brain |
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Functional Differences between Neurons
Interneurons |
Largest class of neurons, never exit CNS
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Functional Differences between Neurons
Motor Neurons |
bipolar - efferent neurons - descending tract, activate muscular & glandular response
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Morphology of Glial Cells
Types of Glial Cells and Function Astrocyte |
glial cell, separates neurons from each other, supplies nutrients to neurons, adheres to capillaries
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Morphology of Glial Cells
Types of Glial Cells and Function Astrocyte provides important ___ ___ ___ which does what? |
blood brain barrier, keeps some toxins from reaching brain.
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Morphology of Glial Cells
Types of Glial Cells and Function Oligodendrocytes |
braind and spinal cord Myelin for CNS
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Morphology of Glial Cells
Types of Glial Cells and Function Schwann Cells |
PNS Myelin
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Morphology of Glial Cells
Types of Glial Cells and Function Microglia |
perform house keeping process - known as phagocytosis
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4 Types of Glial Cells:
1-4 |
1. Astrocytes
2. Oligodendrocytes 3. Schwann cells 4. Microglial Cells |
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Morphology of Glial Cells
____ ____ make up majority of brain. They provide energy & support to ____, but are not ______, themselves. |
Glial Cells,
Neurons, not neurons themselves |
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Morphology of Glial Cells
Sensory neurons are generally monopolar with excpetion of |
smell, hearing, vestibular (sense of balance) - these are bipolar
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Morphological Differences B/T Neurons
Monopolar Neuron (Unipolar) |
single, bifurcating process from soma (sensory)
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Morphological Differences B/T Neurons
Bipolar Neurons |
neuron with 2 processes arising from soma (vestibular)
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Morphological Differences B/T Neurons
Multi-polar Neurons |
neurons with more than 2 processes arising from soma.
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Morphological Differences B/T Neurons
Mitochondria |
Organelles in the terminal boutons responsible for energy generation and protein development
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Morphological Differences B/T Neurons
Grey Matter |
groups of cell bodies
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Morphological Differences B/T Neurons
White Matter |
Myelin coated cells- Myeline sheath
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Morphological Differences B/T Neurons
Synaptic Vessicles - Location Contain? |
Located at ends of terminal boutons,
Contain Neurotransmitters |
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Morphological Differences B/T Neurons
Neurotransmitters |
activate nexxt neuron in chain released into synaptic cleft gap causing next neuron in chain to be activated
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Morphological Differences B/T Neurons
Nodes of Ranvier |
the unmylinated areas between the segments of myelin
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Morphological Differences B/T Neurons
Telodedria |
Long, thin projections at end of the axon
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Morphological Differences B/T Neurons
Terminal Boutons |
End buttons on telodendria
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Morphological Differences B/T Neurons
A neuron typically has 1 ___ but may have many _____, known as the __ __. |
1 axon, many dendrites, dendritic tree
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Morphological Differences B/T Neurons
The junction between the axon and the soma |
axon hillock
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Morphological Differences B/T Neurons
myeline sheath |
white fatty wrapping covers axons, speeds up nerual conduction
destroyed by MS, ALS |
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Neurons
Neurons respond to stimulation, response is mechanism to send: |
information through the nervous system
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Neuron can have 1 of 2 reactions
1. Excitation 2. Inhibition |
1. increase in neuron's activity - active output
2. reduction in neurons activity - cessation of stimulation |
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Neurons
All structures in the nervous system are made up of _______ (____ _____). |
Neurons, nerve cells
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Neurons
Neurons are unique ____ tissue, their function is to __ ___. |
communicating tissue, function to transmit information
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Neurons
The Nervous System is comprised of _ neurons & _ tissue (_ cells.) |
communicative neurons & support tissue ( glial cells)
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Neurons
Structure of most neurons is: |
Soma - cell body
Dendrite - carries info. to cell body Axon - carries ino. away from cell body |
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Developmental divisions of the Nervous system:
By the ___ week of ___ development the brain or ___ is composed of 1, 2, 3 |
4th week of embryonic development
brain/encaphalon is composed of the: prosencephalon -forebrain mesencephalon - midbrain rhombencephelon - hindbrain |
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Developmental divisions of the Nervous system:
Ontogeny recapitulates phylogeny - |
Earliest structures (brain stem) emerge 1st then more advanced structures (cerebral cortex)
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Divisions of the Nervous System
1-3 |
1. Anatomical Divisions
2. Functional Divisions 3. Developmental Divisions |
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Anatomical Division of Nervous System
1. CNS - Central Nervous System 2. PNS- Peripheral Nervous System |
1. brain, spinal cord - all housed within bone (skull or vertebral column)
2. cranial nerves, spinal nerves, sensory receptors most are outside bone. |
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Functional Divisions of Nervous System
Autonomic Nervous System 2 subgroups |
Involuntary bodily functions - heart, digestive
2 subgroups - Sympathetic NS- expends energy Parasympathetic NS - conserves energy |
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Functioal Divisions of Nervous System
Somatic Nervous System 2 subgroups |
Voluntary bodily functions including skeletal (somatic) muscles
Motor component consists of 1. pyramidal system - initiates motor acts 2. Extrapyramidial system - background support |
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The ___ governs voluntary actions
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Cerebrum
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The ____ is responsible for coordinating movement
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Cerebellum
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Proprioception
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the sense of muscle and joint position.
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Ganglia
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groups of cell bodies in the PNS with functional unity
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_____sense is the sense of the body in motion
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Kinesthetic sense
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Special senses include
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Olfaction, Vision, Gustation, and Audition
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The CNS includes the
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Cerebrum, Cerebellum, Subcortical structures, brainstem & spinal cord
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The PNS consists of
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12 pairs of cranial nerves and 31 pairs of spinal nerves as well as the sensory receptors
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The Autonomic Nervous System
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governs involuntary activities of involuntary muscles
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The Somatic Nervous System
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governs voluntary activities
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Information directed toward the brain is termed
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Afferent
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Information directed away from the brain is termed
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Efferent
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Action potential
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the change in electrical potential that occurs when a cell membrane is stimulated adequately to permit ion exchange between the intra and extracellular spaces.
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Nodes of Ranvier
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of the axon myelin promote saltatory conduction
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Higher ognitive processing occurs generally in
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Association Areas
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