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26 Cards in this Set

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Humoral immune system
Cellular immune system
The immune system is divide into 2 parts called what?
Humoral immune system
Involves specific antibodies in the blood and lymph. (The body's humors) Produced by B cells.
Cellular immune system
Involves T cells. That do not produce antibodies but secrete cytokines.
Specialized
__________ lymphocytes respond to intracellular Ags.
Thymus
Where does the T come from in T cells?
thymus gland
T cells mature in the _______ _______. After maturation they migrate to lymphoid tissue.
bursa
Where does the B in B cells come from?
bone marrow
B cells mature in the ____ _______ and fetal liver.
Innate
Acquired
What are the 2 kinds of immunity?
Acquired Immunity
Resistance to infection due to activity of antibodies.
a. Active immunity
b. Passive immunity
antibodies
Acquired immunity
Resistance to infection due to activity of ___________.
Active immunity
means individual is producing its own antibodies
Passive immunity
receiving pre-formed antibodies from someone or something else. (injection or transfusion)
Naturally acquired Active Immunity
Stimulus : Contact with a live microbe by natural processes e.g. infection; illness
Response: symptoms of disease or subclinical RXN. Active production of specific antibodies to the pathogen
Duration: Long term (months to years)sometimes life long. Lots of exceptions: e.g influenza
Contact with a live microbe by natural processes e.g. infection; illness
What is the stimulus in the Naturally acquired Active Immunity?
symptoms of disease or subclinical RXN.

Active production of specific antibodies to the pathogen
What is the response in naturally acquired active immunity?
Long term (months to years)sometimes life long. Lots of exceptions: e.g influenza
What is the duration of the naturally acquired active immunity?
Artificially Acquired Active Immunity
Antigen is intentionally introduced into the body.

1. Stimulus: Vaccines/Immunization
a. Killed pathogens (or their proteins alone)
b. Attenuated/weakened live pathogens
c. Inactivated toxins (toxoids)
2. Response: Production of specific antibodies without developing symptoms of disease (or prodromal symptoms only)
3. Duration: variable (months-years-life time)
Vaccines/Immunization
What is the stimulus for artificially acquired active immunity?
a. Killed pathogens (or their proteins alone)
b. Attenuated/weakened live pathogens
c. Inactivated toxins (toxoids)
What makes up vaccines or immunizations?
Production of specific antibodies without developing symptoms of disease (or prodromal symptoms only)
What is the response for artificially acquired active immunity?
variable (months-years-life time)
What is the duration for artificially acquired active immunity?
Naturally acquired PASSIVE immunity
1. Mother to fetus through the placenta (placental transfer) or in colostrum/milk during nursing. IgG antibody can cross the placenta.
2. Response: No immune response. Acquisition of antibody only.
3. Duration: short term (a few weeks to months)
Naturally acquired PASSIVE immunity
Artificially Acquired PASSIVE immunity
What kind of immunity would have a response that had no immune response and acquisition of antibody only?
Artificially Acquired PASSIVE immunity
1. Antibodies formed in one individual transferred/injected into another individual. Immune serum/gamma globulin/antiserum.
Artificially Acquired PASSIVE immunity
Duration: Very short (2-3 wks)
e.g. venomous snake bites, Tetanus, Hep. A, Diptheria, Botulism.