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42 Cards in this Set
- Front
- Back
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neonate renal dev |
glomerular and tubular dev over 1st 2 years
GFR is decr in neonates and incr over time poor reabs of water and electrolytes > hemoconc |
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neonate hepatic dev
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> neonatal jaundice
incr total and unconj bili |
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no UDP-G prod > jaundice
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Crigler-Najjar
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neonate Endocrine dev
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by Hypothal, pituitary, thyroid/adrenal
primary and secondary probs |
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congenital hypothyroidism
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default in thyroid (primary)
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secondary hypothyroidism
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pituitary wont sercrete TSH
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neonate adrenal probs
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21-hydroxy def> decr aldosterone and cortisol prod
>hypernatremia and decr glc |
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if TDM is < 2
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the liver metabs slower
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if TDM is >2
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liver metabs 2x faster
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geriatric changes
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decr water, muscle, bone density, organs fnx
incr lipids (chol and trigs) |
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incr in Geriatric pts
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K
LD CK GGT AST ALP(women) BUN pCO2 Glc TSH uric acid |
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decr in geriatric pts
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albumin
pO2 bili T3 growth hormone CrCl |
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stays the same in geriatric pts
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Cl-
free T4 Na insulin pH |
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TDM and the elderly
elimination probs |
decr renal mass and blood flow
decr GFR > overdose |
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CSF
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150 ml in adults
prod and reabs at 500 ml/day formation bu ultrafiltrae of plasma and active secr by epithelial membs |
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CSF fnxs
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cushion for brain
maintains constant chem environ removes metab products |
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CSF is
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mostly water
40-70 mg/dl glc .02-.04 protein 280 Na |
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decr glc in CSF with incr lactate
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bact inf
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protein in CSF
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incr in inf = blood brian barrier inf
done by electrophoresis incr in prealbumin |
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serous fluids
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pleural
peritoneal pericardial |
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parietal memb
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lines cavity wall
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visceralmemb
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cover organs
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disruption of seros fluid > increase in vol> effusion
caused by |
effusion
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caused by incr in hydrostatic pressure in pericardial fluid
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CHF
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caused by decr oncotic pressure
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hypoprotein
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caused by incr capillary perm
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inflamation and inf
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systemic disorder that disrupts balance in reg of fluid filtration and reabs btwn serous membs
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transudate
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cond that directly involves teh memb of the cavity
infs and malignancies |
exudate
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clear
<1.015 spg <.5 protein <.6 LD |
transudate
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cloudy
>1.015 spg >.5 protein >.6 LD |
exudate
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> 60 chol
fluid:serum chol >.3 fluid:serum bili >.6 |
pleural exudate
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caused by cirrhosis/hepatic>transudate
bact inf> exudate serum:ascites albumin >1.1 = transudate |
peritoneal
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change in perm of membs due to inf, etc
cardiac compression |
pericardial fluid
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clear pericardial exudate
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metab disorder
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turbid pericardial exudate
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inf or mailg
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milky pericardial exudate
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lymph damage
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bloody pericardial exudate
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memb damage
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incr bloody pericardial exudate
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cardiac punct
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TP
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TP(fluid)/TP(serum)
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LD
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LD(fluid)/LD(serum)
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TP <.5 and LD <.6
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transudate
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TP >.5 and LD > .6
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exudate
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