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48 Cards in this Set

  • Front
  • Back
State the pathway of the reflex arc starting with the Receptor
Receptor> sensory neuron->integration center in brain/interneurons (1or more)->motor neuron->effector (muscle or gland)
Difference between Monosynaptic reflex and Polysynaptic reflex
monosynaptic refles involves just the afferent neuron and efferot neuron

polysynaptic neuron involves afferent neuron then interneuron then efferent neurons.
What is the effect of prostaglandins on the threshold of nociceptors?
prostaglandins lower the threshold of nociceptors
Do nociceptors adapt to sustained or repetitive stimulation?
NO
What are the three categories of nociceptors?
Mechanical- cutting, crushing or pinching

Thermal-temperature

polymodal- respond equally to all kinds of damaging stimuli

irritating chemicals released from injured tissues
Characteristics of FAST pain:

1) what type of stimulation

2) what kind of neurons carry response

3) what kind of pain is produced

4) localization?
1) mechanical, and thermal nciceptors

2)carried by small myelinated A-delta fibers

3) produce sharp pricking pain sensation

4) easily localized
Characteristics of SLOW pain:

1) what type of stimulation

2) what kind of neurons carry response

3) what kind of pain is produced

4) localization?
1) stimulation of polymodal

2) carried by small unmyelinated C fibers

3) dull, aching burning sensation

4) poorly localized
1)Which pain occurs first, FAST or SLOW?


2)Which one lasts longer?
1) Fast

2) Slow
Functions of the cerebral cortex
sensory perception
voluntary control of movement
language
personality traits
sophisticated mental event, such as thinking, memory, decision making creativity and self consciousness
Function of basal nuclei
inhibition of muscle tone
coordination of slow sustained movements
suppression of useless patterns of movement
Function of the Thalamus
relay station for all synaptic input

crude awareness of sensation

some degree of consciousness

role in motor control
Function of Hypothalamus
regulation of many homeostatic functions such as temperature control, thirst, urine output, and food intake

important link between nervous and endocrine system

involvement with emotion and basic behavioral patters

role in sleep wake cycle
Function of cerebellum
maintenance of balance

enhancement of muscle tone

coordination and planning of skilled voluntary muscle activity
Function of the spinal cord
origin of majority of peripheral cranial nerves

cardiovascular respiratory and digestive control centers
muscle reflex involved with equilibrium and posture
arousal and activation of
cerebral cortex

role in sleep wake cycle
group of cell bodies in the CNS are called
Nuclei
group of cell bodies in the PNS are called
ganglia
List the ways the CNS is protected
1) brain enclosed in skull, spine in closed in vertebral column

2) wrapped in 3 protective and nourishing membranes- meningies
a) dura mater
b) arachnoid mater
c) pia mater
3) CSF
4) blood brain barrier
Describe the 3 meningies
Dura mater- thickest and outermost "tough mother"

Arachnoid mater- delicate and vascularized "spider-like mother"

Pia mater -bound tightly to brain
List the space found between the meningies and what is found inside those spaces
Subdural - serous fluid

subarachnoid (between arachnoid membrane and pia mater)- csf and blood vessels
1) how many ventricles are there?

2) where is the cerebrospinal fluid made?

3) what is hydrocephalus?
1) four

2) choroid plexus

3) blockage of CSF flow
What are the names of the ventricles?
1) lateral ventricles or right and left ventricles
2) third ventricle
3) fourth ventricle
Name the area between the 3rd and 4th ventricle

name the area after the 4th ventricle
cerebral aqueduct

central canal
Describe step by step the formation and transfer of CSF
1) formed by choroid plexuses, which projects into lateral, third and fourth ventricles

2) flows through the 4th ventricle and through the spinal cord's central canal

3) moves from teh 4th ventricle to the subarchanoid space to the arcanoid villi which allows it to flow into the dural sinuses
how many times is the entire volume replaced?

what is the normal pressure

what happens if the circulatory process fails?
1) 3

2)10mmHg

3)hydrocephalus
what is the benefit/flaws of blood brain barrier?
1) protects brain from chemical fluctuations. lmits exchange between blood and brain

2)minimizes changes that toxins in blood enter brain
prevents the circulation of hormones that many act like neurotransmitters

3) limits the kinds of drugs that can be used to treat brain and spinal disorders : FLAW
what can cross the blood brain barrier?
water, small lipophilic molecules to freely cross

water soluatble susbtances do not cross easily

lipid soluble substance like o2 and co2, alcohol and steroid hormones cross easily
What are circumventricular organs?
regions in the brain that lack a blood brain barrier
why do circumventricular organs lack a barrier?
to sense the internal milieu of the body or areas involved in regulating or sensing hormones.
Name the circumventricular organs
pineal body- secrets melatonin

neurohypophysis (posterior pituitary)- realease neurohormones

area postrema (medulla oblongata) - vomiting center, get rid of toxins before they hurt you

subfornacal organ- important in regulation of body fluids

median eminence- (part of hypothalamus) regulates anterior pituitary through neurohormones
1) how are cells of the capillary endothelium in the the brain joined?

2) what are ways of exchange between the blood brain barrier?

3) what supposedly directs the tightening of endothelium?
1) tight junctions

2) through endothelial cells wither by endo or exocytosis, protein transport, simple diffusion if the material is membrane soluble

3) astrocytes
what structures are part of the brain stem?
midbrain pons medulla
name the key aspects of the following neuroimaging types:
1) CT
2) MRI
3)SPECT/PET
1) X-RAY
2)protons in magnetic field
3)radiolabled injected compounds
1)What part of the brain controls reticular formation?

2) what is happened with RAS during wakefulness?


3)what is happening to RAS during slow wave sleep?
1) brainstem

2) wakefulness= RAS active and suppressing rhythmic pacemaker neurons in thalamus and cortex

3) slow wave sleep- Ras neuons decrease activity allowing the mergence of synchronous rhythmic activity of thalamic and cortical neurons
Paradoxal sleep (REM)

1) EEG?
2)Motor activity?
3)heart rate, bp respiration?
4) dreaming?
5) arousal?
6) percentage of sleeping time?
7) other important characteristics?
1) like awake person
2)abrupt inhibition of muscle tone, no movement
3)irregular
4)common
5)no easily awoken, but apt to wake spontaneously
6) 20%
7) rapid eye movement
Slow wave sleeping

1) EEG?
2)Motor activity?
3)heart rate, bp respiration?
4) dreaming?
5) arousal?
6) percentage of sleeping time?
7) other important characteristics?
1) slow waves
2) considerable muscle tone, frequent shifting
3) minor reductions
4) rare dreaming
5) easily awakened
6) 80%
7)has four stages
What is EEG and what is it used for?
records postsynaptic activity in cortical neurons

brain waves

clinical tool for diagnosis of cerebral dysfunction
used in legal determination of brain death
used to distinguish between various sleep stages
What kind of waves are seen when eyes are cosed and when they are open?
open= alpha

closed= beta
1)What is the function of the Limbic system?

2) what are the parts of the limbic system?
1) limbic system interconnect the frontal lobe with hypothalamus and lower centers for behavior and memory

2) cingulate gyrus
emotional aspects of pain processing: depression

3) hypocampus: learning and memory. declarative memory

4) amygdala
emotions: fear
expression and recognition of emotions
How are the two hemispheres connected?
corpus callosum and anterior and posterior hippocampal commissure
what is the function of the Supplementary motor area
Plays preparatory role in programming complex sequences of movement
Complex patterns of movement:
Opening or closing hand
what is the function of Premotorcortex
Important in orienting the body and arms toward a specific target
what is the function of Posterior parietal cortex?
Lies posterior to primary somatosensorycortex
When either of these areas is damaged, one can‘t process complex sensory information to accomplish purposeful movement
ie: manipulating eating utensils
1) Corpus callosum interconnects...

2) Association fibers interconnect

3)Projection fibers interconnect
1)left and right cerebral hemispheres

2) functionally distinct areas in same cerebral hemisphere


3) cerebral hemispheres with lower structures such as thalamus
1) functions of broca's area
2) functions wenicke's area
1) speech
2) language comprehension, formulates coherent patters of speech
Language disorders:

1) aphasia

2) speech impediments

3)dyslexia
1) caused by stroke

2)Caused by defect in mechanical aspect of speech
Weakness or incoordinationof muscles controlling vocal apparatus

3) inappropriate interpretation of words
how is aphasias caused
damage to the Broca's and Wernicke's areas disrupts language comprehension or production
Wernicke‘s aphasia occur....
results from damage in temporal-parietal lobe
Broca‘s aphasia occur....
results from damage in frontal lobe