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34 Cards in this Set

  • Front
  • Back
an ordered sequence of events in the life of a dividing eukaryotic cell, composed of mitosis (M) and interphase growth and DNA synthesis phases (G1, S, and G2)
cell cycle
the process that distributes a copt of each chromosome to each new cell during eukaryotic cell division
mitosis
the parts of the eukaryotic cell cycle between cell divisions consisting of growth and DNA synthesis phases G1, S, and G2
interphase
the first growth phase of the cell cycle starting just after DNA synthesis
G1 phase
the second growth phase of the cell cycle beginning after DNA synthesis
G2 phase
synthesis of DNA; the phase of the cell cycle duringwhich DNA, in the form of chromosomes, is duplicated
S
mitosis; the phase of the cell cycle during which mitosis (nuclear division) occurs
M
resisting stage of the cell cycle in which DNA replication and cell division stop
G0 phase
a point of no return in the cell cycle; once this point passes, a cell is committed to a full round of teh cell cycle
restiction point
the division of a cell's nucleus, as in mitosis and meiosis
nuclear division
the division of the cytoplasm of a cell after nuclear division
cytokinesis
specific sequence of DNA at which DNA synthesis begins
replication origins
an enzyme that catalyzes the synthesis of a new DNA strand using one of the original strands as a template
Dna polymerase
a complex of DNA polymerase and other enzymes that catalyzes the synthesis of DNA
Replisome
the basic package of chromatin in eukaryotes made up of DNA wound around a core of histone proteins
nucleosome
in eukaryotes, the chromosonal material (DNA and associated proteins) as it ordinarily appears in a cell's nucleus, with individual chromosomes indistinct
chromatin
a structural change in a gene, a chromosome, or another genetic unti
mutation
causing changes, or mutations, in DNA
mutagenic
a DNA-repair process where enzymes remove a damaged portion of DNA, synthesize a replacement section in place, and attach it to the neighboring DNA segments
excision repair
the replicated copies of a chromosome that are joined by a centromer and that separate during nuclear division
sister chromatins
the specialized region of chromosome that holds two replicated chromosomal strands together and that attatches tot he spindle in mitosis
centromere
separation of the sister chromatids during mitosis in which each new nucleus receives one copy of each chromosome
chromosome segregation
having a number of chromosomes separate and move toward opposite ends of the cell
aneuploid
structure made up of microtubules and proteins, divides the chromatids during nuclear division
mitotic spindle
a dislike structure on the cetromere; links chromosomes to the mitotic spindle
kinetochore
the stage in mitosis and meiosis in which chromosomes move to the center of the spindle, and array of microtubules, and become attatched to it
metaphase
during nuclear division, an imaginary plate that is equidistant between the spindles's two poles
metaphase plate
the stage in cell division in which chromosomes separate and move toward opposite ends of the cell
anaphase
the final stage in mitosis, meiosis I, and meiosis II characterized by two new nuclei forming at opposite ends of the cell; frequently followed by cytokinesis (cell division)
telophase
a group of proteins whose function is to regulate the progression of a cell through the cell cycle and whose concentrations rise and fall throughout the cell cycle
cyclins
the spread of cancer cells from tehir original site to other parts of the body, forming new tumors at distant sites
metastasis
gene that regulates cell division in eukaryotic cells; mutations in these can produce oncogenes, genes having th epotention to produce changes in cellular metabolism, leading to cancerous growth
proto-oncogenes
a gene that inhibits the growth of tumors; deletion or inactivation of such a gene can result in cancer
tumor suppressors
an abrupt halt in the cell cycle when proteins detect mistakes or damage in DNA that needs to be repaired
cell-cycle arrest