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34 Cards in this Set
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an ordered sequence of events in the life of a dividing eukaryotic cell, composed of mitosis (M) and interphase growth and DNA synthesis phases (G1, S, and G2)
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cell cycle
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the process that distributes a copt of each chromosome to each new cell during eukaryotic cell division
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mitosis
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the parts of the eukaryotic cell cycle between cell divisions consisting of growth and DNA synthesis phases G1, S, and G2
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interphase
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the first growth phase of the cell cycle starting just after DNA synthesis
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G1 phase
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the second growth phase of the cell cycle beginning after DNA synthesis
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G2 phase
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synthesis of DNA; the phase of the cell cycle duringwhich DNA, in the form of chromosomes, is duplicated
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S
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mitosis; the phase of the cell cycle during which mitosis (nuclear division) occurs
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M
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resisting stage of the cell cycle in which DNA replication and cell division stop
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G0 phase
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a point of no return in the cell cycle; once this point passes, a cell is committed to a full round of teh cell cycle
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restiction point
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the division of a cell's nucleus, as in mitosis and meiosis
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nuclear division
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the division of the cytoplasm of a cell after nuclear division
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cytokinesis
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specific sequence of DNA at which DNA synthesis begins
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replication origins
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an enzyme that catalyzes the synthesis of a new DNA strand using one of the original strands as a template
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Dna polymerase
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a complex of DNA polymerase and other enzymes that catalyzes the synthesis of DNA
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Replisome
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the basic package of chromatin in eukaryotes made up of DNA wound around a core of histone proteins
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nucleosome
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in eukaryotes, the chromosonal material (DNA and associated proteins) as it ordinarily appears in a cell's nucleus, with individual chromosomes indistinct
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chromatin
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a structural change in a gene, a chromosome, or another genetic unti
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mutation
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causing changes, or mutations, in DNA
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mutagenic
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a DNA-repair process where enzymes remove a damaged portion of DNA, synthesize a replacement section in place, and attach it to the neighboring DNA segments
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excision repair
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the replicated copies of a chromosome that are joined by a centromer and that separate during nuclear division
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sister chromatins
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the specialized region of chromosome that holds two replicated chromosomal strands together and that attatches tot he spindle in mitosis
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centromere
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separation of the sister chromatids during mitosis in which each new nucleus receives one copy of each chromosome
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chromosome segregation
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having a number of chromosomes separate and move toward opposite ends of the cell
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aneuploid
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structure made up of microtubules and proteins, divides the chromatids during nuclear division
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mitotic spindle
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a dislike structure on the cetromere; links chromosomes to the mitotic spindle
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kinetochore
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the stage in mitosis and meiosis in which chromosomes move to the center of the spindle, and array of microtubules, and become attatched to it
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metaphase
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during nuclear division, an imaginary plate that is equidistant between the spindles's two poles
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metaphase plate
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the stage in cell division in which chromosomes separate and move toward opposite ends of the cell
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anaphase
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the final stage in mitosis, meiosis I, and meiosis II characterized by two new nuclei forming at opposite ends of the cell; frequently followed by cytokinesis (cell division)
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telophase
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a group of proteins whose function is to regulate the progression of a cell through the cell cycle and whose concentrations rise and fall throughout the cell cycle
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cyclins
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the spread of cancer cells from tehir original site to other parts of the body, forming new tumors at distant sites
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metastasis
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gene that regulates cell division in eukaryotic cells; mutations in these can produce oncogenes, genes having th epotention to produce changes in cellular metabolism, leading to cancerous growth
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proto-oncogenes
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a gene that inhibits the growth of tumors; deletion or inactivation of such a gene can result in cancer
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tumor suppressors
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an abrupt halt in the cell cycle when proteins detect mistakes or damage in DNA that needs to be repaired
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cell-cycle arrest
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