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53 Cards in this Set

  • Front
  • Back

exteroreceptors

respond to external stimuli impinging on the skin

proprioception

Perception of body projections and movement (including info from muscles, joint capsules, ligaments, tendons, and vestibular system)



More deeply situated by groups I-a, I-b, and II afferents



Nervous system must compare output to muscle with input from muscle and tendons

proprioceptors

more deeply situated



signal the status of muscles, tendons, and joints

interoreceptors

located within the viscera



respond to changes in the internal environment

light touch

Detected by cutaneous extero-receptors that are rapidly adapting (detect transient events)



Transmitted by A-beta fibers

gross touch

Detected by cutaneous extra-receptors that are rapidly adapting (detect transient events)



Transmitted by A-beta and A-delta fibers

temperature receptors

Separate sets of fibers and thermoreceptors that respond to increases and decreases in skin temperature



Slowly adapting neurons



Cold receptors: A-delta and C fibers
Warmth receptors: unmyelinated afferents

fast pain

Pain from cutaneous tissues comes from A-delta fibers

slow pain

Pain from cutaneous tissues comes from C fibers

adaption rate

ability of an afferent to rapidly or slowly adapt to a constant stimulus

rapidly adapting

Discharges briefly, then stops



Potentials at start and end of stimulus



Transient or high frequency events

slowly adapting

Discharges for the duration of the stimulus



Maintained events

I-a fibers

Fast conduction axons involved in muscle stretch, primary spindle receptors in proprioception

A-beta fibers

Large diameter, more rapidly conducting axons



Supply majority of touch receptors

A-delta fibers

Large diameter, conduct slightly slower than A-beta



Touch, temperature, and pain

Pelage hair receptors

Supplied by A-beta fibers that are quickly adapting


Discharge briefly at the onset of hair bending, and some also discharge when the hair returns to the normal position


No sustained discharge if hair is bent for more than a few seconds


​Parallel to hair shafts and consist of neuritis (nerve terminals) and bordered by Schwann cell cytoplasm

Vibrissae receptors

variety of rapidly adapting and slowly adapting receptors supplies vibrissae

vibrissae

whiskers, sinus hairs, or tactile hairs



most are present on the upper lip or muzzle, chin, and above the eyes, but also present on other parts of the body in some taxa (manatees)

rapidly adapting touch receptors

transduce low intensity mechanical deformation of the skin

Pacinian corpuscles

Located primarily in subcutaneous tissue



Fast adapting A-beta touch fibers



Laminated with central neurotic, sensitive to minimal gingival or skin distortion



More sensitive


Meissner's corpuscles

Located superficially within dermal papillae of glabrous skin


Fast adapting A-beta touch fibers


Less sensitive than Pacinian corpuscles


Laminated and supplied by several neuritis that intertwine through the lamellae

Merkel cell

Slowly adapting skin receptor



Located in hairy skin of the face, glabrous skin of the hand, and the closely related gingival mucosa

dorsal columns

Make up one functionally distinct ascending pathway


Gracile fasciculus and cuneate fasciculus


Transmit information related to fine touch and proprioception from the trunk and limbs


Comprised mostly of primary dorsal root afferents that ascend ipsilaterally to the medulla


Major input from rapidly adapting muscle, joint, hair, and touch receptors

gracile fasciculus

located in the dorsal columns



receives input from the sacral, lumbar, and lower thoracic roots, representing the lower trunk and legs

cuneate fasciculus

added lateral to the fascicles gracilis at mid-thoracic cord levels



transmits input from the upper trunk, arms, and neck

lemniscal tracts

cuneate and gracile fasciculi



ascending projections to the thalamus travel in the medial lemniscus

spinothalamic tract

Formed by axons that cross the spinal cord at levels in which their cell bodies are located



Interruption reduces pain and temp sensations contra laterally, targets ventrocaudal thalamus

spinoreticular tract

Many fibers terminate in medullary reticular formation, some relay in midbrain reticular formation, involved in arousal and motivational-affective reactions to nociceptive stimulation

Dorsal column pathway (hindlimb and caudal trunk)

DRGC -> gracile fasiculus -> synapse in gracile nucleus -> cross as internal arcuate fibers -> medial lemniscus -> VCL -> internal capsule -> somatosensory cortex

Dorsal column pathway (forelimb and cranial trunk)

DRGC -> cuneate fasiculus -> synapse in cuneate fasiculus -> cross as internal arcuate fibers -> medial lemniscus -> VCL -> internal capsule -> somatosensory cortex

internal arcuate fibers

Axons from cells in dorsal column nuclei



Cross to other side of brainstem and form medial lemniscus


spinocerebellar system

primary afferents that synapse on neurons in the dorsal horn


in thoracic, lumbar and sacral levels of the cord, the axons of these dorsal horn neurons enter the dorsal and ventral spinocerebellar tracts and terminate in the cerebellum


at cervical levels, the dorsal horn axons travel in the rostral spinocerebellar tract

dorsal column senses

light/fine touch, proprioception of trunk and limbs

Ventral quadrant pathways

DRGC -> dorsal horn cells -> crossed spinothalamic tract -> VCL -> internal capsule -> somatosensory cortex
DRGC -> dorsal horn cells -> crossed spinoreticulthalamic tract -> reticular formation, IL, hypothalamus -> IL to internal capsule -> widespread cortical areas

Ventral quadrant senses

pain, temperature, crude touch

Face somesthetic pathway (light touch)

Trigeminal ganglion cells -> trigeminal nerve -> prinicpal/chief sensory nucleus -> joins medial lemniscus -> VCM -> somatosensory cortex

Face somesthetic pathway (proprioception from muscles of mastication)

Mesencephalic nucleus -> spinal tract of V -> trigeminal nerve -> muscles of mastication
Mesencephalic nucleus cells have peripheral processes in muscle proprioceptors, cell bodies in mesencephalon, and central processes terminating in motor nucleus of V

Face somesthetic pathway (crude touch, pain, temp)

Trigeminal ganglion cells -> spinal trigeminal tract -> spinal trigeminal nucleus then:
a. crossed spinothalamic tract -> VCM -> internal capsule -> somatosensory cortex
b. crossed spinoreticulothalamic tract -> reticular formation, IL, hypothalamus -> IL to internal capsule -> widespread cortical areas
c. some cross and join medial lemniscus -> VCM -> somatosensory cortex

motor pathways

Motor nucleus of V -> motor neurons to muscles of mastication
Trigeminal nerve -> muscles of mastication

somesthesis

body sensibility or somatosensory capacities

reticular

most primitive motor system

tooth pulp

Contains endings of A-delta and C afferents -> pain



A-beta afferents -> non-painful sensations
Directly sensitive to mechanical disturbances

dentin

Radially oriented tubules with odontoblasts protruding in at dento-pulpal interface
Changes in hydrodynamic pressure in tubules cause odontoblast to move -> afferents -> pain
A-delta = sharp localized pain
C = diffuse, poorly localized aching

trigeminal ganglion

cell bodies of receptors which innervate facial skin and oral cavity, analogous to dorsal root ganglia; reflects 3 incoming branches (V1, 2, 3)

Subnucleus oralis


Division of V spinal nucleus
Represents oral cavity (tooth pulp, gingival, palate, buccal mucosa)
Mediates oral cavity reflexes (chewing and defensive)

Subnucleus interpolaris


Division of V spinal nucleus
Represents head and oral cavity
Mediates tactile facial reflexes

Subnucleus caudalis

Division of V spinal nucleus
Complete representation of face and oral cavity
Relay of pain and thermal sensation

Trunk and limb projections (from VCL)

terminate medially

Oral and facial projections (from VCM)

terminate more laterally

SI (primary somatosensory cortex)

Complete map of body represented in postcruciate gyrus, projects to primary motor cortex (MI)

cutaneous receptors

Subserve tactile sensation

deep receptors

joints and proprioception

muscle afferents

info about contractile status