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4 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Amiloride
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MOA - Inhibits Na+ transport channels at the collecting duct and the late distal tubule
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PK - Combined with thiazides reduces toxicity risks
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Amiloride
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CU - Mineralcorticoid excess (Conn’s syndrome/secondary aldosteronism)
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T - Hyperchloremic metabolic acidosis, hyperkalemia; contraindicated in hyperkalemia, liver disease
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Triamterene
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MOA - Inhibits Na+ transport channels at the collecting duct and the late distal tubule
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PK - Poorly soluble; combined with thiazides reduces toxicity risks
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Triamterene
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CU - Mineralcorticoid excess (Conn’s syndrome/secondary aldosteronism)
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T - Hyperchloremic metabolic acidosis, hyperkalemia, kidney stones; contraindicated in hyperkalemia, liver disease
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