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8 Cards in this Set
- Front
- Back
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Sodium Bicarbonate Classification
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-Alkalinizing agent
-Antacid -Electrolyte |
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Sodium Bicarbonate Mechanism of Action
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-Increases plasma bicarbonate
-buffers excess hydrogen ion concentration -Raises blood pH -Reverses clinical manifestations of acidosis |
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Sodium bicarbonate Indications
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-Known preexisting hyperkalemia
-preexisting metabolic acidosis -Overdose: tricyclic antidepressants, procainamide |
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Sodium Bicarbonate Dosing
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-Initial dose 1 mEq/kg IV bolus.
-1/2 initial dose may be repeated every 10 minutes thereafter -repeated IV doses of 1 to 2 mEq/kg may be needed when sodium bicarbonate is used to treat drug-induced arrhythmias and hypotension |
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Sodium Bicarbonate Precautions
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-Extravasation may lead to tissue inflammation and necrosis
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Sodium Bicarbonate Contraindications
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-Significant metabolic or respiratory alkalosis
-Severe pulmonary edema |
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Sodium Bicarbonate Special Considerations
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-Don't mix with parenteral drugs b/c of possiblility of drug inactivation or precipitation
-Hyperkalemia produces ECG changes (peaked T waves; widenend QRS, prolonged PR intervals, flattened ST segments, flattened or absent P waves) -used in hyperkalemia to decrease serum K+ levels by temporarily shifting K+ into the intracellular fluid -may be administered in tricyclic antidepressant overdose with QRS prolongatoin or hypotension. -Drug given to maintain arterial pH between 7.45-7.55 |
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Sodium Bicarbonate Onset / Duration
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-2 to 10 minutes
-30 to 60 minutes |
