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19 Cards in this Set
- Front
- Back
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What is the effect of nicotine on metabolism?
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- nicotine induces enzymes and increases catecholamines.. this can lead to weight loss/control
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lobeline (Bantron, Nikoban)
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nicotine-like substance.. Butt-out caps 500mg lobelia
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silver acetate (Tabinil Mouth wash)
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reacts with nicotine and produces a bitter taste in mouth
- Smokerette lozenge (6mg silver acetate) |
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What are the side effects of Nicorette gum?
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- throat irritation
- mouth sores - burping/hiccups - jaw fatigue - HEART BURN - nausea |
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How to dose nicorette gum?
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1st month: 1 for every cig, 1 for every 2-3 cig
2nd month: ...1 for every 4-5 cig 3rd month: ... 2 a day, d/c |
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What strength of gum should a smoker start at for nicorette, 2mg or 4mg?
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2mg - if they light up after 30 min of waking
4mg - light up within 30 min |
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Compare the nicotine patch to the gum
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With respect to dynamics of nicotine levels..
Patch is never enough to satisfy the spikes that gum can give - but hopefully the patch gives enough to hold you off |
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How to use patch?
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Apply to upper body / outer upper arm / hip
Change daily at the same time Don't reuse sites within 7 days |
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What are the topical side effects of the patch?
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topical reaction (50%)
headache, insomnia, nausea.. these are effects of nicotine withdrawal |
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What are the 3 stages for nicoderm patch?
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Stage 1 - 21mg for 6 wk
Stage 2 - 14mg for 2 weeks Stage 3 - 7mg for 2 wk |
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When to start patch at 14mg??
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Nicoderm: CV disease, <45kg, <1/2 pack a day
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How many Thrive lozenges do most users need? What is the upper limit?
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Most users need 10 lozenges per day.
Do not exceed 15 of the 2mg or 25 of the 1mg lozenges per day. |
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How is bupropion SR (zyban/wellbutrin) titrated?
What is the main concern (side effects) of using bupropion? |
Day 1-3: 150mg OD
Day 4-7: 150mg BID Can increase risk of seizures at 300mg/day.. also CI with MAOIs |
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What is Rimonabant?
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cannabinoid receptor antagonist
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What is clonidine?
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- anti-hypertensive
- works centrally to control BP |
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What is varenicline (Champix)?
How is it used? Side effects? |
- partial nicotine agonist
Dosing: titrate... 0.5mg OD Day 1-3; 0.5mg BID days 4-7; Day 8, 1mg BID... stop smoking Day 7-14 Side effects: nausea, weird dreams, constipation, drowsiness... depression??? |
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Value of varenicline + NRT?
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not much b/c they both occupy the same receptor sites
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What are some behavioral tips for preparing to quit?
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- smoking after you brush your teeth
- using your other hand - switching brands - emptying ashtrays - change seating in house - RULE OF 3.. wait 3 minutes after you get a craving |
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What are the appropriate uses of soy protein-based formulas?
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infants fed vegan diets, infants with galactosemia
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