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14 Cards in this Set
- Front
- Back
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what is small pox?
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a terrifying natural infection of man
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what is the smallpox vaccine?
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an artificial infection that prevents smallpox
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what is cowpox?
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an exotic zoonosis
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what are the names of the 2 small pox strains?
Which one is worse? |
1. Variola major - kills 25-50% of infected! Much worse.
2. Variola minor - only <1% |
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What is the incubation period of smallpox?
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12-14 days
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How is smallpox spread?
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Via the respiratory tract
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How does smallpox infect a person?
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goes through resp tract to lymphatic system. Viremic in all tissues.
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What are the damaging effects of viremic smallpox?
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-Macule
-Papules with Guarnieri bodies -Necrosis -Scarring/secondary infection |
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What are the diagnostic features of smallpox?
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1. History of exposure
2. Febrile prodrome 2-4 days 3. Typical rash |
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What are the 4 clinical types of smallpox?
What are the fatality rates in each? |
1. Hemorrhagic; 100% fatal
2. Flat; often fatal 3. Ordinary; 1-50% fatal 4. Modified; varies |
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What 3 factors affect the prognosis of smallpox infectino?
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1. Clinical type
2. Strain type (major/minor) 3. Age |
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Where does the smallpox vaccine come from?
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calves
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How long is the vaccine effective?
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3-5 yrs
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What are drawbacks of the vaccine?
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Encephalitis, generalized vaccine, can kill if given in first year of life.
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